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pro vyhledávání: '"Zsolt Ruszics"'
ADEVO: Proof-of-concept of adenovirus-directed EVOlution by random peptide display on the fiber knob
Autor:
Erwan Sallard, Julian Fischer, Katrin Schroeer, Lisa-Marie Dawson, Nissai Beaude, Arsalene Affes, Eric Ehrke-Schulz, Wenli Zhang, Adrian Westhaus, Marti Cabanes-Creus, Leszek Lisowski, Zsolt Ruszics, Anja Ehrhardt
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 4, Pp 200867- (2024)
Directed evolution of viral vectors involves the generation of randomized libraries followed by artificial selection of improved variants. Directed evolution only yielded limited results in adenovirus (AdV) engineering until now, mainly due to insuff
Externí odkaz:
https://doaj.org/article/7378372d93384fac88c9836d1e27cc67
The human adenovirus E3/19K protein is a type I transmembrane glycoprotein of the endoplasmic reticulum (ER) that abrogates cell surface transport of major histocompatibility complex class I (MHC-I) and MHC-I-related chain A and B (MICA/B) molecules.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff89099e8ea74e9e53cd938e7061fed1
https://europepmc.org/articles/PMC3648096/
https://europepmc.org/articles/PMC3648096/
