Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Zsolt Mártonfalvi"'
Autor:
Jaime Andrés Rivas-Pardo, Yong Li, Zsolt Mártonfalvi, Rafael Tapia-Rojo, Andreas Unger, Ángel Fernández-Trasancos, Elías Herrero-Galán, Diana Velázquez-Carreras, Julio M. Fernández, Wolfgang A. Linke, Jorge Alegre-Cebollada
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Testing mechanical forces on native molecules in natural environments remains a challenge. Here the authors engineer titin to carry a HaloTag-TEV insertion to allow analysis of dynamics under force in muscle fibers.
Externí odkaz:
https://doaj.org/article/3fc2e404086144d88118c34e7a917844
Autor:
Dominik Sziklai, Judit Sallai, Zsombor Papp, Dalma Kellermayer, Zsolt Mártonfalvi, Ricardo H. Pires, Miklós S. Z. Kellermayer
Publikováno v:
Nanomaterials, Vol 12, Iss 2, p 178 (2022)
Titin is a multifunctional filamentous protein anchored in the M-band, a hexagonally organized supramolecular lattice in the middle of the muscle sarcomere. Functionally, the M-band is a framework that cross-links myosin thick filaments, organizes as
Externí odkaz:
https://doaj.org/article/72e54c4d75634babb920d5298385c583
Publikováno v:
Entropy, Vol 16, Iss 8, Pp 4322-4337 (2014)
The exclusion zone (EZ) is a boundary region devoid of macromolecules and microscopic particles formed spontaneously in the vicinity of hydrophilic surfaces. The exact mechanisms behind this remarkable phenomenon are still not fully understood and ar
Externí odkaz:
https://doaj.org/article/eba8ad6b43d74241b3a359109d78455b
Autor:
Zsolt Mártonfalvi, Miklós Kellermayer
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85847 (2014)
Titin is a giant elastomeric protein responsible for the generation of passive muscle force. Mechanical force unfolds titin's globular domains, but the exact structure of the overstretched titin molecule is not known. Here we analyzed, by using high-
Externí odkaz:
https://doaj.org/article/185eccdcdfc84b7db9590dc37aefc04b
Autor:
Cristina M. Șulea, Zsolt Mártonfalvi, Csilla Csányi, Dóra Haluszka, Miklós Pólos, Bence Ágg, Roland Stengl, Kálmán Benke, Zoltán Szabolcs, Miklós S. Z. Kellermayer
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7561
Fibrillin-1 microfibrils are essential elements of the extracellular matrix serving as a scaffold for the deposition of elastin and endowing connective tissues with tensile strength and elasticity. Mutations in the fibrillin-1 gene (FBN1) are linked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83cceaed8768ca025e46a214b08f7c35
Autor:
Alexander G. Bobylev, Elmira I. Yakupova, Liya G. Bobyleva, Nikolay V. Molochkov, Alexander A. Timchenko, Maria A. Timchenko, Hiroshi Kihara, Alexey D. Nikulin, Azat G. Gabdulkhakov, Tatiana N. Melnik, Nikita V. Penkov, Michail Y. Lobanov, Alexey S. Kazakov, Miklós Kellermayer, Zsolt Mártonfalvi, Oxana V. Galzitskaya, Ivan M. Vikhlyantsev
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1056
A giant multidomain protein of striated and smooth vertebrate muscles, titin, consists of tandems of immunoglobulin (Ig)- and fibronectin type III (FnIII)-like domains representing β-sandwiches, as well as of disordered segments. Chicken smooth musc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e301cf5357ef15490a66ed9e2f30f7
Autor:
Dorottya Mudra, György Török, Gabriella Csík, Levente Herényi, Zsolt Mártonfalvi, Bálint Kiss, Miklós S.Z. Kellermayer
Publikováno v:
Biophysical Reviews
The development of advanced experimental methodologies, such as optical tweezers, scanning-probe and super-resolved optical microscopies, has led to the evolution of single-molecule biophysics, a field of science that allows direct access to the mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200cf0eb1f0275f6d58c8a6f14fa6ae1
https://doi.org/10.1007/s12551-020-00747-9
https://doi.org/10.1007/s12551-020-00747-9
Autor:
Dominik Sziklai, Eszter Lakatos, Miklós S.Z. Kellermayer, Zsombor Papp, Zsolt Mártonfalvi, Brennan Decker
Publikováno v:
Journal of Structural Biology. 203:46-53
Titin is a giant protein spanning between the Z- and M-lines of the sarcomere. In the A-band titin is associated with the myosin thick filament. It has been speculated that titin may serve as a blueprint for thick-filament formation due to the super-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab843700e032a3f29f2b2debed3a9e5
https://doi.org/10.1016/j.jsb.2018.05.001
https://doi.org/10.1016/j.jsb.2018.05.001
Autor:
Miklós S.Z. Kellermayer, Pasquale Bianco, Zsolt Mártonfalvi, György G. Ferenczy, Katalin Naftz
Publikováno v:
Protein Science. 26:1380-1390
Titin is a giant protein that provides elasticity to muscle. As the sarcomere is stretched, titin extends hierarchically according to the mechanics of its segments. Whether titin's globular domains unfold during this process and how such unfolded dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c10172f17a03ead2f999efabeebbedea
https://doi.org/10.1002/pro.3117
https://doi.org/10.1002/pro.3117
Autor:
Julio M. Fernandez, Yong Li, Ángel Fernández-Trasancos, Elías Herrero-Galán, Jorge Alegre-Cebollada, Zsolt Mártonfalvi, Wolfgang A. Linke, Rafael Tapia-Rojo, Jaime Andrés Rivas-Pardo, Diana Velázquez-Carreras, Andreas Unger
Publikováno v:
Circulation Research. 125
Single-molecule methods using recombinant proteins have generated transformative hypotheses on how mechanical forces interact with titin in the sarcomere, enabling muscle contraction. However, testing these mechanical hypotheses on native titin in it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4de03872973f644293cf52d5e2f54f3
https://doi.org/10.1161/res.125.suppl_1.330
https://doi.org/10.1161/res.125.suppl_1.330