Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Zsolt Bodai"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Programmable double-strand DNA breaks (DSBs) can be harnessed for precision genome editing through manipulation of the homology-directed repair (HDR) pathway. Here the authors report the development of the double tap - double tap implements secondary
Externí odkaz:
https://doaj.org/article/254830d1927141acbd0de90b8e5767f7
Autor:
Alena L. Bishop, Víctor López Del Amo, Emily M. Okamoto, Zsolt Bodai, Alexis C. Komor, Valentino M. Gantz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
CRISPR gene drives are genetic elements capable of quickly spreading through populations and they offer promising solutions for curbing the spread of vector-borne diseases and controlling crop pest and invasive species populations. Here the authors p
Externí odkaz:
https://doaj.org/article/bad9dc227a0746a1a7492c5a98f8ac9d
Autor:
Stefan Antonowicz, Zsolt Bodai, Tom Wiggins, Sheraz R. Markar, Piers R. Boshier, Yan Mei Goh, Mina E. Adam, Haonan Lu, Hiromi Kudo, Francesca Rosini, Robert Goldin, Daniela Moralli, Catherine M. Green, Chris J. Peters, Nagy Habib, Hani Gabra, Rebecca C. Fitzgerald, Zoltan Takats, George B. Hanna
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Volatile aldehydes can be enriched in esophageal adenocarcinoma patients’ breath. Here, the authors reveal corresponding metabolic changes in EAC tumours, which may be caused by impaired detoxification of endogenous metabolites.
Externí odkaz:
https://doaj.org/article/c4cb39fcd5d245a5814461336da92aeb
Autor:
Diana Marcus, David L. Phelps, Adele Savage, Julia Balog, Hiromi Kudo, Roberto Dina, Zsolt Bodai, Francesca Rosini, Jacey Ip, Ala Amgheib, Julia Abda, Eftychios Manoli, James McKenzie, Joseph Yazbek, Zoltan Takats, Sadaf Ghaem-Maghami
Publikováno v:
Cancers, Vol 14, Iss 23, p 5892 (2022)
Introduction: Delays in the diagnosis and treatment of endometrial cancer negatively impact patient survival. The aim of this study was to establish whether rapid evaporative ionisation mass spectrometry using the iKnife can accurately distinguish be
Externí odkaz:
https://doaj.org/article/0d375dea1be548189383168663cef908
Autor:
Edward R. St John, Julia Balog, James S. McKenzie, Merja Rossi, April Covington, Laura Muirhead, Zsolt Bodai, Francesca Rosini, Abigail V. M. Speller, Sami Shousha, Rathi Ramakrishnan, Ara Darzi, Zoltan Takats, Daniel R. Leff
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-14 (2017)
Abstract Background Re-operation for positive resection margins following breast-conserving surgery occurs frequently (average = 20–25%), is cost-inefficient, and leads to physical and psychological morbidity. Current margin assessment techniques a
Externí odkaz:
https://doaj.org/article/2f8f974a073943a883917cb74ab7f0c9
Autor:
Ilkka Kalliala, David A. MacIntyre, Sarah Bowden, Julia Balog, Maria Kyrgiou, James S. McKenzie, Anita Mitra, A Savage, Maria Paraskevaidi, Sadaf Ghaem-Maghami, Marcell Szasz, Phillip R. Bennett, Deirdre Lyons, Konstantinos Lathouras, Menelaos Tzafetas, Zsolt Bodai, Zoltan Takats, Francesca Rosini
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Clearance of surgical margins in early cervical cancer prevents the need for adjuvant chemoradiation and associated morbidity and allows fertility preservation. Clearance of disease is also crucial in the surgical management of local rec
Autor:
Stefan Antonowicz, Nima Abbassi-Ghadi, Zsolt Bodai, Tom Wiggins, Sheraz Markar, Piers Boshier, Yan Mei Goh, Mina Adam, Haonan Lu, Hiromi Kudo, Francesca Rosini, Robert Goldin, Daniella Moralli, Catherine Green, Chris Peters, Nagy Habib, Hani Gabra, Rebecca Fitzgerald, Zoltan Takats, George Hanna
Publikováno v:
British Journal of Surgery. 108
Background Exhaled breath analysis is a promising approach for oesophageal adenocarcinoma (OAC) early detection. The biomarkers of interest are low molecular weight metabolites including volatile aldehydes. In this translational study we investigated
Autor:
Alena L. Bishop, Víctor López Del Amo, Emily M. Okamoto, Zsolt Bodai, Alexis C. Komor, Valentino M. Gantz
Publikováno v:
Nature communications, vol 13, iss 1
Homing CRISPR gene drives could aid in curbing the spread of vector-borne diseases and controlling crop pest and invasive species populations due to an inheritance rate that surpasses Mendelian laws. However, this technology suffers from resistance a
Autor:
Afeez Adebesin, Ara Darzi, Lauren Ford, James Kinross, Zoltan Takats, Eftychios Manoli, Sam E Mason, Zsolt Bodai
Publikováno v:
Analytical Chemistry
In this study, we integrate rapid evaporative ionization mass spectrometry (REIMS) with the Harmonic scalpel, an advanced laparoscopic surgical instrument that utilizes ultrasound energy to dissect and coagulate tissues. It provides unparalleled mani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96feab4c0feae0d52e61ac9e4ddc68ad
http://hdl.handle.net/10044/1/89767
http://hdl.handle.net/10044/1/89767
Autor:
Christopher J. Peters, Haonan Lu, Mina E. Adam, Piers R. Boshier, Hani Gabra, George B. Hanna, Tom Wiggins, Zoltan Takats, Zsolt Bodai, Francesca Rosini, Nagy A. Habib, Robert D. Goldin, Yan Mei Goh, Sheraz R. Markar, Hiromi Kudo, Catherine M. Green, Daniela Moralli, Rebecca C. Fitzgerald, Stefan Antonowicz
Publikováno v:
Nature Communications
Nature Communications, 2021, Nature Communications, 12, pp.1454. ⟨10.1038/s41467-021-21800-5⟩
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, 2021, Nature Communications, 12, pp.1454. ⟨10.1038/s41467-021-21800-5⟩
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Volatile aldehydes are enriched in esophageal adenocarcinoma (EAC) patients’ breath and could improve early diagnosis, however the mechanisms of their production are unknown. Here, we show that weak aldehyde detoxification characterizes EAC, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde4d8176f94933989732c77b01de3be
http://hdl.handle.net/10044/1/93988
http://hdl.handle.net/10044/1/93988