Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Zsolt Ablonczy"'
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162596 (2016)
In diabetic individuals, macular edema is a major cause of vision loss. This condition is refractory to insulin therapy and has been attributed to metabolic memory. The retinal pigment epithelium (RPE) is central to maintaining fluid balance in the r
Externí odkaz:
https://doaj.org/article/0b35a67e10874d28a4204db600e78046
Autor:
Taariq Mohammed, Yuehong Tong, Julia Agee, Nayanika Challa, Rainer Heintzmann, Martin Hammer, Christine A. Curcio, Thomas Ach, Zsolt Ablonczy, R. Theodore Smith
Publikováno v:
Vision, Vol 2, Iss 4, p 38 (2018)
To characterize fluorophore signals from drusen and retinal pigment epithelium (RPE) and their changes in age related macular degeneration (AMD), the authors describe advances in ex vivo hyperspectral autofluorescence (AF) imaging of human eye tissue
Externí odkaz:
https://doaj.org/article/3299d99105144c77a892b62c9d4fa13c
Autor:
Jie Gong, Mark A Fields, Ernesto F Moreira, Hannah E Bowrey, Monika Gooz, Zsolt Ablonczy, Lucian V Del Priore
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143272 (2015)
Compared with many induced pluripotent stem cell (iPSC) lines generated using retrovirus and other non-integrating methods, the utilization of human protein-induced iPSC (piPSC) lines may provide a safer alternative for the generation of retinal pigm
Externí odkaz:
https://doaj.org/article/cd0cde89eaeb432188b84a77099c01e7
Autor:
Eliza Barnwell, Vasudevaraju Padmaraju, Robert Baranello, Javier Pacheco-Quinto, Craig Crosson, Zsolt Ablonczy, Elizabeth Eckman, Christopher B Eckman, Viswanathan Ramakrishnan, Nigel H Greig, Miguel A Pappolla, Kumar Sambamurti
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91531 (2014)
BACE1 (β-secretase) and α-secretase cleave the Alzheimer's amyloid β protein (Aβ) precursor (APP) to C-terminal fragments of 99 aa (CTFβ) and 83 aa (CTFα), respectively, which are further cleaved by γ-secretase to eventually secrete Aβ and A
Externí odkaz:
https://doaj.org/article/3e3c856aacf8479196377dffa67b13e4
Autor:
M. Wade Calcutt, Yiannis Koutalos, Zsolt Ablonczy, Richard M. Caprioli, Anne Hanneken, David M. Anderson, Rosalie K. Crouch, Kevin L. Schey, Jeffrey M. Spraggins
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
Stargardt disease is a juvenile onset retinal degeneration, associated with elevated levels of lipofuscin and its bis-retinoid components, such as N-retinylidene-N-retinylethanolamine (A2E). However, the pathogenesis of Stargardt is still poorly unde
Autor:
Christine A. Curcio, Yuehong Tong, Zsolt Ablonczy, Thomas Ach, Rainer Heintzmann, Guido Gerig, R. Theodore Smith, Sungmin Hong, Tal Ben Ami
Publikováno v:
Retina. 36:S127-S136
Purpose To elucidate the molecular pathogenesis of age-related macular degeneration (AMD) and interpretation of fundus autofluorescence imaging, the authors identified spectral autofluorescence characteristics of drusen and retinal pigment epithelium
Autor:
John E. Donello, Rosalie K. Crouch, Patrick Pallitto, Yiannis Koutalos, Julia E Herrmann, E. Ellen Jones, Zsolt Ablonczy, Richard R. Drake
Publikováno v:
Photochemical & Photobiological Sciences. 14:1888-1895
The accumulation of lipofuscin, an autofluorescent aging marker, in the retinal pigment epithelium (RPE) has been implicated in the development of age-related macular degeneration (AMD). Lipofuscin contains several visual cycle byproducts, most notab
Autor:
Rainer Heintzmann, Yuehong Tong, Thomas Ach, Zsolt Ablonczy, Julia Agee, Nayanika Challa, Roland Theodore Smith, Christine A. Curcio, Taariq Mohammed, Martin Hammer
Publikováno v:
Vision, Vol 2, Iss 4, p 38 (2018)
Vision
Volume 2
Issue 4
Vision
Volume 2
Issue 4
To characterize fluorophore signals from drusen and retinal pigment epithelium (RPE) and their changes in age related macular degeneration (AMD), the authors describe advances in ex vivo hyperspectral autofluorescence (AF) imaging of human eye tissue
Autor:
Jingwen Cai, Zsolt Ablonczy, C. James Chou, Yutao Liu, Masakii Ishii, Bärbel Rohrer, Navjot Shah, Carlene Brandon
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1864(8)
Retinal pigment epithelium (RPE) alterations in age-related macular degeneration occur in patches, potentially involving long-distance communication between damaged and healthy areas. Communication along the epithelium might be mediated by extracellu
Publikováno v:
Experimental Eye Research. 137:50-56
Diabetic macular edema (DME) is a major cause of visual impairment. Although DME is generally believed to be a microvascular disease, dysfunction of the retinal pigment epithelium (RPE) can also contribute to its development. Advanced glycation end-p