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Publikováno v:
Genes & cancer, vol 11, iss 1-2
Genes & Cancer
Genes & Cancer
While many genes specifically act as oncogenes or tumor suppressors, others are tumor promoters or suppressors in a context-dependent manner. Here we will review the basic-helix-loop-helix (BHLH) protein BHLHE40, (also known as BHLHB2, STRA13, DEC1,
Autor:
Clare Proudfoot, Andreas Kuznik, Chieh I. Chen, Kaleb Michaud, Marie Fournier, Peter Gal, Zsofia Kiss, Noemi Muszbek
Publikováno v:
Advances in Therapy
Introduction Assess the cost-effectiveness (US healthcare payer perspective) of sarilumab subcutaneous (SC) 200 mg + methotrexate versus conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs) or targeted DMARD + methotrexate for mod
Autor:
Charlie Gourley, Nichola Roebuck, Kiera Heffernan, Robert L Hollis, Zsofia Kiss, Helen Starkie-Camejo
Publikováno v:
Ovarian cancer.
Introduction/Background Niraparib is an oral, highly selective poly(ADP-ribose) polymerase inhibitor (PARPi). The PRIMA/ENGOT-OV26/GOG-3012 trial intention-to-treat population included stage III and IV ovarian cancer (OC) patients post-primary or int
Autor:
Arif Muhammad Khan, Muhammad Ashfaq, Zsofia Kiss, Azhar Abbas Khan, Shahid Mansoor, Bryce W Falk
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73657 (2013)
The citrus mealybug, Planococcus citri, is an important plant pest with a very broad plant host range. P. citri is a phloem feeder and loss of plant vigor and stunting are characteristic symptoms induced on a range of host plants, but P. citri also r
Externí odkaz:
https://doaj.org/article/4498e2ff0c9043df847f31fcbdde10dd
Publikováno v:
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 24(4)
Objectives\ud This research aims to explore how often the National Institute for Health and Care Excellence (NICE) uses immature overall survival data to inform reimbursement decisions on cancer treatments, and the implications of this for resource a
Autor:
Clare Proudfoot, Chieh I. Chen, Zsofia Kiss, Noemi Muszbek, Peter Gal, Kaleb Michaud, Marie Fournier, Andreas Kuznik
Publikováno v:
Journal of managed carespecialty pharmacy. 25(11)
Despite a substantial number of treatment options in rheumatoid arthritis (RA) following tumor necrosis factor inhibitor (TNFi) inadequate response or intolerance (TNF-IR), a lack of clarity on the optimal approach remains. Sarilumab, a human monoclo
Autor:
Paramita M. Ghosh, Zsofia Kiss
Publikováno v:
Endocrine-related cancer, vol 23, iss 11
The androgen receptor (AR) plays a key role in the development and progression of prostate cancer (CaP). Since the mid-1990s, reports in the literature pointed out higher incidences of CaP in some select groups, such as airline pilots and night shift
Autor:
Mary Saunders, Amir Sahabi, David J. Olivos, Randy P. Carney, Lin Tian, Yann Thillier, Zsofia Kiss, Alisha Knudson, Ruiwu Liu, Kit S. Lam, Jean Carlos Heleno Campos
Publikováno v:
ACS combinatorial science, vol 19, iss 5
Membrane active peptides (MAPs) represent a class of short biomolecules that have shown great promise in facilitating intracellular delivery without disrupting cellular plasma membranes. Yet their clinical application has been stalled by numerous fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f022bca15c037af8b8d6410c0e2fb05
https://europepmc.org/articles/PMC5901688/
https://europepmc.org/articles/PMC5901688/