Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Zsofia, Botyanszki"'
Autor:
Neel Joshi, Erisa Hysi, Peter Q. Nguyen, Zsofia Botyanszki, Martin G. Nussbaumer, Pei Kun R. Tay, Alexander Naydich
Publikováno v:
ChemCatChem. 9:4328-4333
Cell-free biocatalysis systems offer many benefits for chemical manufacturing, but their widespread applicability is hindered by high costs associated with enzyme purification, modification, and immobilization on solid substrates, in addition to the
Autor:
Neel Joshi, Martin G. Nussbaumer, Peter Q. Nguyen, Zsofia Botyanszki, Pei Kun Richie Richie Tay
Publikováno v:
Biotechnology and Bioengineering. 112:2016-2024
Biocatalytic transformations generally rely on purified enzymes or whole cells to perform complex transformations that are used on industrial scale for chemical, drug, and biofuel synthesis, pesticide decontamination, and water purification. However,
Publikováno v:
Biotechnology and Bioengineering
Biocatalytic transformations generally rely on purified enzymes or whole cells to perform complex transformations that are used on industrial scale for chemical, drug, and biofuel synthesis, pesticide decontamination, and water purification. However,
Autor:
Kamil Godula, Raghuveer Parthasarathy, Zsofia Botyanszki, David Rabuka, Marissa L. Umbel, Carolyn R. Bertozzi
Publikováno v:
Journal of the American Chemical Society
Quantifying and controlling the orientation of surface-bound macromolecules is crucial to a wide range of processes in areas as diverse as biology, materials science, and nanotechnology. Methods capable of directing orientation, as well as an underst
Autor:
Christopher W. Harland, David Rabuka, Carolyn R. Bertozzi, Zsofia Botyanszki, Raghuveer Parthasarathy
Publikováno v:
Langmuir. 25:5193-5198
Lipid-derived desiccation resistance in membranes is a rare, unique ability previously observed only with trehalose dimycolate (TDM), an abundant mycobacterial glycolipid. Here we present the first synthetic trehalose glycolipids capable of providing
Publikováno v:
Nature Communications. 5
The significant role of biofilms in pathogenicity has spurred research into preventing their formation and promoting their disruption, resulting in overlooked opportunities to develop biofilms as a synthetic biological platform for self-assembling fu
Autor:
Julie A. Leary, Cynthia M. Holsclaw, Sarah A. Gilmore, Zsofia Botyanszki, Jessica C. Seeliger, Michael W. Schelle, Benjamin F. Cravatt, Michael Niederweis, Carolyn R. Bertozzi, Sarah E. Tully
Publikováno v:
The Journal of Biological Chemistry
Background: Sulfolipid-1 (SL-1) is a Mycobacterium tuberculosis outer membrane lipid whose biosynthesis is not fully understood. Results: Chp1 catalyzes two acyl transfer reactions to form SL-1. Sap modulates SL-1 levels and transmembrane transport.
Autor:
Michael W. Schelle, Brian L. Carlson, Christopher R. Behrens, Fiona L. Lin, Cynthia M. Holsclaw, Carolyn R. Bertozzi, Julie A. Leary, Pawan Kumar, Zsofia Botyanszki, Stavroula K. Hatzios
Publikováno v:
The Journal of Biological Chemistry
Mycobacterium tuberculosis possesses an unusual cell wall that is replete with virulence-enhancing lipids. One cell wall molecule unique to pathogenic M. tuberculosis is polyacyltrehalose (PAT), a pentaacylated, trehalose-based glycolipid. Little is
Autor:
Raghuveer Parthasarathy, Zsofia Botyanszki, David Rabuka, Christopher W. Harland, Carolyn R. Bertozzi
Publikováno v:
Biophysical Journal. (3):164a
We have recently demonstrated that the glycolipid trehalose dimycolate (TDM), a major outer membrane component of dehydration resistant Mycobacterium tuberculosis (MTb), can impart significant dehydration resistance to supported phospholipid membrane