Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Zsófia Dubrovay"'
Autor:
Anita Horváth, Kristóf Bolla, Alexandra Wachtler, Lilla Maksó, Máté Papp, Sándor Mahó, Zsófia Dubrovay, János Kóti, Rita Skoda-Földes
Publikováno v:
ACS Omega, Vol 6, Iss 41, Pp 26846-26856 (2021)
Externí odkaz:
https://doaj.org/article/8c597458d1624363a543d60f78b3486e
Autor:
Alexandra Wachtler, Rita Skoda-Földes, Sándor Mahó, Máté Papp, Anita Horváth, Zsófia Dubrovay, Kristóf Bolla, Lilla Maksó, János Kóti
Publikováno v:
ACS Omega, Vol 6, Iss 41, Pp 26846-26856 (2021)
ACS Omega
ACS Omega
The ring opening of 2α,3α- and 2β,3β-epoxy-5α-androstan-17-one with halide reagents (AlCl3, TMSCl, LiCl, and LiBr) was investigated using imidazolium ionic liquids in the dual role of solvent and catalyst. The application of the ionic liquid was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e85885f170be842444665fdfff346b4
https://doaj.org/article/8c597458d1624363a543d60f78b3486e
https://doaj.org/article/8c597458d1624363a543d60f78b3486e
Publikováno v:
Letters in Drug Design & Discovery. 16:1248-1257
Background: Aryl-methoxybenzaldehydes substituted in various positions may serve as valuable starting materials for the synthesis of biologically active compounds. Methods: Biaryl-methoxybenzaldehydes and pyridyl-aryl-methoxybenzaldehydes were synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3093fbd3b49229ba62b9b8c6f6898881
https://doi.org/10.2174/1570180816666181106123809
https://doi.org/10.2174/1570180816666181106123809
Autor:
Andrea Német-Hanzelik, Zsófia Dubrovay, György Keglevich, István Greiner, Hedvig Bölcskei, Viktor Háda
Publikováno v:
Letters in Drug Design & Discovery. 14:233-239
The benzyloxy-benzyl moiety is a valuable building block in medicinal chemistry, e.g. in case of the voltage gated sodium channel blockers Safinamide and Ralfinamide. To prepare further derivatives a series of (iodobenzyl)oxybenzaldehydes (3a-3i) use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b663be153950adcf68d414d5dd7e968c
https://doi.org/10.2174/1570180813666160804142245
https://doi.org/10.2174/1570180813666160804142245
Autor:
András Keglevich, József Molnár, Ana Martins, Péter Keglevich, Zsófia Dubrovay, Áron Szigetvári, Laszlo Hegedus, Judit Gyenese, Csaba Szántay, Lilla Péter, Attila Hunyadi, Miklós Dékány, László Hazai
Publikováno v:
Current Organic Chemistry. 20:2639-2646
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82179daf28c0c5a6b045ec54ce53a0b4
https://doi.org/10.2174/1385272820666160617080202
https://doi.org/10.2174/1385272820666160617080202
Autor:
András Keglevich, Zita Hegedüs, László Hazai, Zoltán Bánóczi, Ildikò Szabò, József Tóvári, Péter Keglevich, Áron Szigetvári, Zsófia Lengyel, Csaba Szántay, Zsófia Dubrovay, Ivan Ranđelović, Ferenc Hudecz, Viktor Háda, Fruzsina L. Regenbach, Álmos Gorka-Kereskényi
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 24(10)
Some Vinca alkaloids (eg, vinblastine, vincristine) have been widely used as antitumor drugs for a long time. Unfortunately, vindoline, a main alkaloid component of Catharanthus roseus (L.) G. Don, itself, has no antitumor activity. In our novel rese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d485d69ff6f0e98a4c01723c762206
https://pubmed.ncbi.nlm.nih.gov/30084214
https://pubmed.ncbi.nlm.nih.gov/30084214
Autor:
Viktor Háda, Zsófia Dubrovay, Janos Galambos, Zoltán Gulyás, Csaba Szántay, Antal Aranyi, Ágnes Lakó-Futó
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 84:309-322
In the course of exploring the possibilities of developing a new, improved process at Gedeon Richter for the production of the "bisindole" alkaloids vinblastine (VLB) and vincristine (VCR), some novel VLB/VCR-related trace impurities were detected by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc2c9b0fc6efaf2cf09617c6f151ecb
https://doi.org/10.1016/j.jpba.2012.09.008
https://doi.org/10.1016/j.jpba.2012.09.008
Autor:
Zsófia Dubrovay, Viktor Háda
In this chapter, we describe the NMR- and MS-based structure elucidation of a new impurity of the bisindole alkaloid vincristine (VCR). Owing to its size and internal conformational dynamics, VCR and its derivatives are highly “NMR-unfriendly” ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c6c9c8a7aa1424ef62a679d198c541d
https://doi.org/10.1016/b978-0-12-419963-7.00011-0
https://doi.org/10.1016/b978-0-12-419963-7.00011-0
Autor:
Zoltán Béni, Ádám Demeter, Miklós Dékány, Zsófia Dubrovay, Lars G. Hanson, Viktor Háda, János Kóti, Zsuzsanna Sánta, Zoltán Szakács, Csaba Szántay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3f649b3cda36bebc47cd782e0c1f30
https://doi.org/10.1016/b978-0-12-419963-7.09990-9
https://doi.org/10.1016/b978-0-12-419963-7.09990-9
Autor:
Tímea Imre, Pál Szabó, Eniko Takacs, V. Pongracz, Júlia Kovári, Angéla Békési, Zsófia Dubrovay, Imre Zagyva, Beáta G. Vértessy, Orsolya Barabas
Publikováno v:
Journal of Biological Chemistry. 279:17932-17944
dUTPase is responsible for preventive DNA repair via exclusion of uracil. Developmental regulation of the Drosophila enzyme is suggested to be involved in thymine-less apoptosis. Here we show that in addition to conserved dUTPase sequence motifs, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7eb8c134f72287392185a10a56fc238
https://doi.org/10.1074/jbc.m313643200
https://doi.org/10.1074/jbc.m313643200