Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Zsigmond Benko"'
Publikováno v:
Pathogens, Vol 13, Iss 7, p 566 (2024)
Fission yeast, a single-cell eukaryotic organism, shares many fundamental cellular processes with higher eukaryotes, including gene transcription and regulation, cell cycle regulation, vesicular transport and membrane trafficking, and cell death resu
Externí odkaz:
https://doaj.org/article/d2186c73f30a46248869c0438a0328f7
Autor:
Tomas Selicky, Matus Jurcik, Barbora Mikolaskova, Alexandra Pitelova, Nina Mayerova, Miroslava Kretova, Michaela Osadska, Jan Jurcik, Roman Holic, Lenka Kohutova, Jana Bellova, Zsigmond Benko, Juraj Gregan, Silvia Bagelova Polakova, Peter Barath, Lubos Cipak, Ingrid Cipakova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12800 (2022)
Pre-mRNA splicing plays a fundamental role in securing protein diversity by generating multiple transcript isoforms from a single gene. Recently, it has been shown that specific G-patch domain-containing proteins are critical cofactors involved in th
Externí odkaz:
https://doaj.org/article/ad4b5678e9874b089d03bcff14c59dce
Autor:
Jiantao Zhang, Kasey Vernon, Qi Li, Zsigmond Benko, Anthony Amoroso, Mohamed Nasr, Richard Y. Zhao
Publikováno v:
Pathogens, Vol 10, Iss 7, p 804 (2021)
Successful combination antiretroviral therapies (cART) eliminate active replicating HIV-1, slow down disease progression, and prolong lives. However, cART effectiveness could be compromised by the emergence of viral multidrug resistance, suggesting t
Externí odkaz:
https://doaj.org/article/a94c65cdb08541178396ed4f2700e457
Autor:
Silvia Polakova, Lucia Molnarova, Randy W Hyppa, Zsigmond Benko, Ivana Misova, Alexander Schleiffer, Gerald R Smith, Juraj Gregan
Publikováno v:
PLoS Genetics, Vol 12, Iss 6, p e1006102 (2016)
To identify new proteins required for faithful meiotic chromosome segregation, we screened a Schizosaccharomyces pombe deletion mutant library and found that deletion of the dbl2 gene led to missegregation of chromosomes during meiosis. Analyses of b
Externí odkaz:
https://doaj.org/article/e82663668f1542be9e4c8fb247dd9c79
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151286 (2016)
BACKGROUND:HIV-1 protease (PR) is an essential viral enzyme. Its primary function is to proteolyze the viral Gag-Pol polyprotein for production of viral enzymes and structural proteins and for maturation of infectious viral particles. Increasing evid
Externí odkaz:
https://doaj.org/article/8248cff04f9f4b0691ff34430f572a9d
Autor:
Zsigmond Benko, Richard Y. Zhao
Publikováno v:
BioTechniques, Vol 51, Iss 1, Pp 57-60 (2011)
Complementation of auxotrophic nutrient deficiencies in minimal media is widely used for selection of exogenous gene introduction to fission yeast. However, only a limited number of such selection markers are available. Antibiotic resistance markers
Externí odkaz:
https://doaj.org/article/4685802fd4a64f08a03095f44be861a5
Autor:
Lubos Cipak, Karoline Pichlerova, Nina Mayerova, Zsigmond Benko, Martin Prevorovsky, Anna Jordakova, Silvia Polakova, Juraj Gazdarica, Juraj Gregan, Alexandra Pitelova, Ivana Misova, Maria Smondrkova, Tomáš Szemes, Lucia Strieskova, Jaroslav Budis, Tatiana Sedlackova
Publikováno v:
Nucleic Acids Research
During homologous recombination, Dbl2 protein is required for localisation of Fbh1, an F-box helicase that efficiently dismantles Rad51–DNA filaments. RNA-seq analysis of dbl2Δ transcriptome showed that the dbl2 deletion results in upregulation of
Autor:
Lubos Cipak, Silvia Polakova, Zsigmond Benko, Juraj Gregan, Andrea Sevcovicova, Barbora Huraiova, Gustav Ammerer, Dorothea Anrather, Juan Mata, Judit Kanovits, Caia D. S. Duncan
Publikováno v:
Cell Cycle. 19:1777-1785
Meiosis is the process by which haploid gametes are produced from diploid precursor cells. We used stable isotope labeling by amino acids in cell culture (SILAC) to characterize the meiotic proteome in the fission yeast Schizosaccharomyces pombe. We
Publikováno v:
Curr HIV Res
Background:HIV-1 protease inhibitor (PI) is one of the most potent classes of drugs in combinational antiretroviral therapies (cART). When a PI is used in combination with other anti- HIV drugs, cART can often suppress HIV-1 below detection thus prol
Autor:
Mohamed Nasr, Qi Li, Jiantao Zhang, Zsigmond Benko, Anthony Amoroso, Richard Y. Zhao, Kasey Vernon
Publikováno v:
Pathogens
Volume 10
Issue 7
Pathogens, Vol 10, Iss 804, p 804 (2021)
Volume 10
Issue 7
Pathogens, Vol 10, Iss 804, p 804 (2021)
Successful combination antiretroviral therapies (cART) eliminate active replicating HIV-1, slow down disease progression, and prolong lives. However, cART effectiveness could be compromised by the emergence of viral multidrug resistance, suggesting t