Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zsófia Tömböl"'
Autor:
Melinda R. Bendes, Peter Igaz, Zsófia Tömböl, Károly Rácz, Adrienn Zsippai, Péter Szabó, Diana Rita Szabó
Publikováno v:
Orvosi Hetilap. 151:1163-1170
A mellékvesekéreg-carcinoma ritka, rossz prognózisú daganat. Döntően sporadikus előfordulású, de ismertek nagyon ritka öröklődő formái is, amelyek a patogenezis megértésében nagy segítséget nyújtanak. A mellékvesekéreg-daganatok
Publikováno v:
Current Bioinformatics. 5:81-88
Effects of mitotane on gene expression in the adrenocortical cell line NCI-H295R: a microarray study
Autor:
Éva Pállinger, András Falus, Attila Patócs, Péter Szabó, Peter Igaz, Sára Tóth, R. C. Gaillard, Zsófia Tömböl, Diana Rita Szabó, Adrienn Zsippai, Katalin Éder, Károly Rácz
Publikováno v:
Pharmacogenomics. 13(12)
Aim: The adrenolytic agent mitotane is widely used in the treatment of adrenocortical cancer; however, its mechanism of action is poorly elucidated. We have studied mitotane-induced mRNA expression changes in the NCI-H295R adrenocortical cancer cell
Autor:
Adrienn, Zsippai, Diana Rita, Szabó, Peter M, Szabó, Zsófia, Tömböl, Melinda R, Bendes, Zoltán, Nagy, Károly, Rácz, Peter, Igaz
Publikováno v:
American journal of cancer research. 1(5)
Adrenocortical cancer is a rare tumor and its prognosis is poor. Although numerous tumor-associated genetic and signal transduction alterations have been described to date, its pathogenesis is still unclear. Hybridization-based DNA microarray approac
Autor:
Viktor Molnár, Péter Szabó, Peter Igaz, Zoltán Wiener, Zsófia Tömböl, Barbara Érsek, András Falus
Publikováno v:
Cellular and molecular life sciences : CMLS. 69(5)
MicroRNAs provide an additional layer in the regulation of gene expression acting as repressors with several targets at the posttranscriptional level. This study describes microRNA expression patterns during differentiation and activation of mast cel
Autor:
Gergely Rácz, Katalin Éder, Attila Patócs, Peter Igaz, Miklós Tóth, András Falus, Péter Szabó, Zsófia Tömböl, István Likó, Janina Kulka, Károly Rácz, Attila Kovács, Attila Zalatnai
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 23(12)
MicroRNAs are involved in the pathogenesis of several tumors, however, there have been no data on microRNA expression in pheochromocytomas to date. The objective of our study was to perform microRNA expression profiling in sporadic and hereditary ben
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 16(10)
In their elegant study published in the December 15, 2009 issue of Clinical Cancer Research , Soon and colleagues described differences in the microRNA expression profiles of adrenocortical tumors (ACT) and established predictors for poor prognosis.
Autor:
Attila Patócs, Miklós Tóth, Peter Igaz, Zsófia Tömböl, András Falus, Péter Szabó, Csaba Szalai, K Kövesdi, Márton Andrásfalvy, Károly Rácz, Viola Tamasi, Viktor Molnár, R Farkas
Publikováno v:
Oncogene. 29(21)
Sporadic adrenocortical tumours are common, but their pathogenesis is poorly elucidated. In this study, we present a meta-analysis and review of gene expression microarray and comparative genome hybridization (CGH) studies performed to date on these
Autor:
Zoltán Wiener, Peter Igaz, Péter Szabó, Károly Rácz, Zsófia Tömböl, András Falus, Janina Kulka, Péter Riesz, Péter Pócza, Attila Kovács, Attila Patócs, Miklós Tóth, János Horányi, Rolf C. Gaillard
Publikováno v:
Virchows Archiv : an international journal of pathology. 455(2)
Histamine is involved in the pathogenesis of several tumors; however, there are no data on its possible involvement in human adrenocortical tumorigenesis. The expression of genes and proteins involved in the biosynthesis (histidine decarboxylase, HDC
Publikováno v:
Current medicinal chemistry. 15(26)
Cushing's syndrome is a rare disease with significant morbidity and mortality. Surgical intervention represents the most effective treatment option in both adrenocorticotropin-dependent and -independent forms of hypercortisolism. It is not uncommon,