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Autor:
Beth, Borowsky, Margaret M, Durkin, Kristine, Ogozalek, Mohammad R, Marzabadi, John, DeLeon, Bharat, Lagu, Rainer, Heurich, Harvey, Lichtblau, Zoya, Shaposhnik, Irena, Daniewska, Thomas P, Blackburn, Theresa A, Branchek, Christophe, Gerald, Pierre J, Vaysse, Carlos, Forray
Publikováno v:
Nature Medicine. 8:825-830
Melanin concentrating hormone (MCH) is an orexigenic hypothalamic neuropeptide, which plays an important role in the complex regulation of energy balance and body weight. Here we show that SNAP-7941, a selective, high-affinity MCH1 receptor (MCH1-R)