Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Zowi R Huinen"'
Autor:
Gal Markel, Michal J Besser, Eytan Ruppin, Oscar Krijgsman, Daniel S Peeper, Judit Díaz-Gómez, Ettai Markovits, David W Vredevoogd, Georgi Apriamashvili, Pierre L Levy, Sanju Sinha, Zowi R Huinen, Nils L Visser, Beaunelle de Bruijn, Julia Boshuizen, Susan E van Hal-van Veen, Maarten A Ligtenberg, Onno B Bleijerveld, Chun-Pu Lin, Santiago Duro Sánchez, Juan Simon Nieto, Alex van Vliet, Maarten Altelaar
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 11 (2024)
Background Blockade of the programmed cell death protein 1 (PD-1) immune checkpoint (ICB) is revolutionizing cancer therapy, but little is known about the mechanisms governing its expression on CD8 T cells. Because PD-1 is induced during activation o
Externí odkaz:
https://doaj.org/article/b3b1db25d0594fcdad82ad2a293ad050
Autor:
Patrycja Nowak-Sliwinska, Judy R. van Beijnum, Christian J. Griffioen, Zowi R. Huinen, Nadine Grima Sopesens, Ralph Schulz, Samir V. Jenkins, Ruud P. M. Dings, Floris H. Groenendijk, Elisabeth J. M. Huijbers, Victor L. J. L. Thijssen, Eric Jonasch, Florry A. Vyth-Dreese, Ekaterina S. Jordanova, Axel Bex, René Bernards, Tanja D. de Gruijl, Arjan W. Griffioen
Publikováno v:
Angiogenesis. Springer Netherlands
Nowak-Sliwinska, P, van Beijnum, J R, Griffioen, C J, Huinen, Z R, Sopesens, N G, Schulz, R, Jenkins, S V, Dings, R P M, Groenendijk, F H, Huijbers, E J M, Thijssen, V L J L, Jonasch, E, Vyth-Dreese, F A, Jordanova, E S, Bex, A, Bernards, R, de Gruijl, T D & Griffioen, A W 2022, ' Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy ', Angiogenesis . https://doi.org/10.1007/s10456-022-09863-4
Angiogenesis, 26(2), 279-293. Springer Netherlands
Nowak-Sliwinska, P, van Beijnum, J R, Griffioen, C J, Huinen, Z R, Sopesens, N G, Schulz, R, Jenkins, S V, Dings, R P M, Groenendijk, F H, Huijbers, E J M, Thijssen, V L J L, Jonasch, E, Vyth-Dreese, F A, Jordanova, E S, Bex, A, Bernards, R, de Gruijl, T D & Griffioen, A W 2022, ' Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy ', Angiogenesis . https://doi.org/10.1007/s10456-022-09863-4
Angiogenesis, 26(2), 279-293. Springer Netherlands
Purpose Ongoing angiogenesis renders the tumor endothelium unresponsive to inflammatory cytokines and interferes with adhesion of leukocytes, resulting in escape from immunity. This process is referred to as tumor endothelial cell anergy. We aimed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1fd56259da385781a1fbb2ca7f1c118
https://research.vumc.nl/en/publications/9161280f-a17f-4174-aa72-1ff4ff8957d1
https://research.vumc.nl/en/publications/9161280f-a17f-4174-aa72-1ff4ff8957d1
Autor:
Patrycja Nowak-Sliwinska, Elisabeth J. M. Huijbers, Arjan W. Griffioen, Zowi R. Huinen, Judy R. van Beijnum
Publikováno v:
Huinen, Z R, Huijbers, E J M, van Beijnum, J R, Nowak-Sliwinska, P & Griffioen, A W 2021, ' Anti-angiogenic agents — overcoming tumour endothelial cell anergy and improving immunotherapy outcomes ', Nature Reviews Clinical Oncology, vol. 18, no. 8, pp. 527-540 . https://doi.org/10.1038/s41571-021-00496-y
Immune checkpoint inhibitors have revolutionized medical oncology, although currently only a subset of patients has a response to such treatment. A compelling body of evidence indicates that anti-angiogenic therapy has the capacity to ameliorate anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bce0b48f02401c0a7e4efd74041ecd6
https://research.vumc.nl/en/publications/6e164432-1aa7-4992-af47-0ee6c48ab4e0
https://research.vumc.nl/en/publications/6e164432-1aa7-4992-af47-0ee6c48ab4e0
Autor:
Kelly Boelaars, Ernesto Rodriguez, Zowi R. Huinen, Chang Liu, Di Wang, Babet O. Springer, Katarzyna Olesek, Laura Goossens-Kruijssen, Thomas van Ee, Dimitri Lindijer, Willemijn Tak, Aram de Haas, Laetitia Wehry, Joline P. Nugteren-Boogaard, Aleksandra Mikula, Charlotte M. de Winde, Reina E. Mebius, David A. Tuveson, Elisa Giovannetti, Maarten F. Bijlsma, Manfred Wuhrer, Sandra J. van Vliet, Yvette van Kooyk
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Despite recent advances in cancer immunotherapy, pancreatic ductal adenocarcinoma (PDAC) remains unresponsive due to an immunosuppressive tumor microenvironment, which is characterized by the abundance of cancer-associated fibroblasts (CAFs)
Externí odkaz:
https://doaj.org/article/89d397e7c86647f4a8efdf005a8b83cc