Výsledky vyhledávání - "Zourab Bebia"

Safety and immunogenicity of an investigational maternal trivalent group B streptococcus vaccine in pregnant women and their infants: Results from a randomized placebo-controlled phase II trial

Autor: Torri D. Metz, Immaculada Margarit, Ouzama Henry, James D. Campbell, Richard H. Beigi, Giada Buffi, David E. Soper, Annette Dreisbach, Maria Lattanzi, Luca Grassano, Zourab Bebia, Annette Karsten, Kathryn M. Edwards, Geeta K. Swamy

Publikováno v: Vaccine. 38(44)

Background This study evaluated the safety and immunogenicity of an investigational trivalent group B streptococcus (GBS) vaccine in US pregnant women, transplacental serotype-specific antibody transfer and persistence in infants, and serotype-specif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08eb780de5904593e05c36a4a2f8a23f
https://pubmed.ncbi.nlm.nih.gov/32883555

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Safety and immunogenicity of fully liquid and lyophilized formulations of an investigational trivalent group B streptococcus vaccine in healthy non-pregnant women: Results from a randomized comparative phase II trial

Autor: Sherryl Baker, Casey P. Johnson, Jan de Hoon, Corinne Vandermeulen, Claudia Seidl, James Peterson, Jiri Beran, Zourab Bebia, Maria Lattanzi, Annette Karsten, Annette Dreisbach, Ouzama Henry, Geert Leroux-Roels, Bartholomew Corsaro, Pierre Van Damme, Mohamed S. Al-Ibrahim

Publikováno v: Vaccine

BACKGROUND: We evaluated the safety and immunogenicity of liquid and lyophilized formulations of an investigational trivalent group B streptococcus (GBS) vaccine in non-pregnant women and assessed the formulations' equivalence in terms of serotype-sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ba80d5471517d0c09e7e2e199cb69f
https://hdl.handle.net/10067/1685660151162165141

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Safety and Immunogenicity of a Second Dose of an Investigational Maternal Trivalent Group B Streptococcus Vaccine in Nonpregnant Women 4-6 Years After a First Dose: Results From a Phase 2 Trial

Autor: Annelies Aerssens, Ouzama Henry, Cathy Maes, Immaculada Margarit, Geert Leroux-Roels, Giada Buffi, A. Karsten, Luca Grassano, Karen S. Slobod, Stephen Cho, Fien De Boever, Bartholomew Corsaro, Zourab Bebia

Publikováno v: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

Background Maternal immunization against group B streptococcus (GBS) could protect infants from invasive GBS disease. Additional doses in subsequent pregnancies may be needed. We evaluated the safety and immunogenicity of a second dose of an investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3fe53eb04553bc21f548a719ec4d27f
https://pubmed.ncbi.nlm.nih.gov/31394571

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Recombinant follicle-stimulating hormone (follitropin alfa) for ovulation induction in Japanese patients with anti-estrogen-ineffective oligo- or anovulatory infertility: results of a phase II dose-response study

Autor: Takumi Yanaihara, Yuji Taketani, Yasunori Yoshimura, Zourab Bebia, Kazumichi Andoh, Hideki Mizunuma, Eduardo Kelly, Hidekazu Saito, Hiroshi Hoshiai, Minoru Irahara

Publikováno v: Reproductive Medicine and Biology. 9:91-97

To determine the optimal regimen of recombinant human follicle-stimulating hormone (r-hFSH) for ovulation induction (OI) in Japanese women with amenorrhea I or anovulatory infertility.In this randomized, double-blind, dose-finding study, women aged 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160cfbd8dcbee161b48e7c7d3715dd0f
https://doi.org/10.1007/s12522-009-0044-7

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Adenovirus-Directed Expression of Functional Luteinizing Hormone (LH) Receptors in Undifferentiated Rat Granulosa Cells: Evidence for Differential Signaling through Follicle-Stimulating Hormone and LH Receptors1

Autor: Guoquan Liu, Lynda Ihrig, Zourab Bebia, Jeremy P. Somers, Andrew Shenker, Anthony J. Zeleznik

Publikováno v: Endocrinology. 142:2252-2259

This study was conducted to determine the feasibility of using replication-defective adenovirus vectors to express receptors for LH. Two vectors were constructed, one that directs the expression of wild-type human LH receptor (LHr; AdRSVLHrwt) and an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9cfdd1b021c26576f5ab71d306a5cb3
https://doi.org/10.1210/endo.142.6.8017

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Bioequivalence revisited: influence of age and sex on CYP enzymes

Autor: Reginald F. Frye, Marjorie Romkes, Zourab Bebia, Shama Buch, Diego Chaves-Gnecco, Alfred A. Cecchetti, John W Wilson, Robert A. Branch

Publikováno v: Clinical pharmacology and therapeutics. 76(6)

Background and objective The activity of cytochrome P450 (CYP) enzymes, which determine the rate of elimination of lipid-soluble drugs, demonstrates considerable interindividual variability. The extent to which age and sex influence CYP activity rema

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6323ac9e37ee4acf33c57cfb0fde288f
https://pubmed.ncbi.nlm.nih.gov/15592333

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Coordinated intrahepatic and extrahepatic regulation of cytochrome p4502D6 in healthy subjects and in patients after liver transplantation

Autor: Robert A. Branch, Joseph A. Carcillo, Marjorie Romkes, Kenneth E. Thummel, John W. Wilson, Reginald F. Frye, Adedayo Adedoyin, Zourab Bebia, Gilbert J. Burckart, Carmela Knoll, Lorin Roskos, Raman Venkataramanan, Susan Sereika

Publikováno v: Clinical pharmacology and therapeutics. 73(5)

Cytochrome P450 (CYP) 2D6 activity exhibits wide intersubject variation even among individuals with similar genotypes in whom the active enzyme is expressed. There is, therefore, a need to understand the mechanisms involved in determining its activit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42cefd623910431d081ce168215d6b3b
https://pubmed.ncbi.nlm.nih.gov/12732845

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