Výsledky vyhledávání - "Zorka Mikloska"

Immature Monocyte-Derived Dendritic Cells Are Productively Infected with Herpes Simplex Virus Type 1

Autor: Lidija Bosnjak, Anthony L. Cunningham, Zorka Mikloska

Publikováno v: Journal of Virology. 75:5958-5964

Herpes simplex viruses (HSV) have developed several immunoevasive strategies. Here we demonstrate a novel mechanism by which HSV type 1 may interfere with the immune response through infection of immature dendritic cells (DC) and selective downmodula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d01ae08ddf7d8f25db6111002d81e9
https://doi.org/10.1128/jvi.75.13.5958-5964.2001

Zobrazit plný text záznamu

Herpes simplex virus type 1 glycoproteins gB, gC and gD are major targets for CD4 T-lymphocyte cytotoxicity in HLA-DR expressing human epidermal keratinocytes

Autor: Zorka Mikloska, Anthony L. Cunningham

Publikováno v: Journal of General Virology. 79:353-361

T lymphocytes are the main mediators of the protective immune response in recurrent herpes simplex. Early in the development of recurrent lesions, macrophages and CD4 T lymphocytes predominate in the mononuclear infiltrate surrounding infected epider

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c0d0d7d5209b85c6b9f6621cd82b0f
https://doi.org/10.1099/0022-1317-79-2-353

Zobrazit plný text záznamu

Herpes Simplex Virus Protein Targets for CD4 and CD8 Lymphocyte Cytotoxicity in Cultured Epidermal Keratinocytes Treated with Interferon-γ

Autor: Zorka Mikloska, Alison M. Kesson, Anthony L. Cunningham, Mark E. T. Penfold

Publikováno v: The Journal of Infectious Diseases. 173:7-17

In early recurrent herpetic lesions, CD4 T lymphocytes are the predominant infiltrating cells, and keratinocytes expressing major histocompatibility complex (MHC) class II antigens, induced byinterferon-y (lFN-1'), are the major siteof herpes simplex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838e4f3a96fd8c08f82adb5666b15aa2
https://doi.org/10.1093/infdis/173.1.7

Zobrazit plný text záznamu

Alpha and Gamma Interferons Inhibit Herpes Simplex Virus Type 1 Infection and Spread in Epidermal Cells after Axonal Transmission

Autor: Zorka Mikloska, Anthony L. Cunningham

The ability of alpha interferon (IFN-α) and IFN-γ to inhibit transmission of herpes simplex virus type 1 (HSV-1) from neuronal axon to epidermal cells (ECs), and subsequent spread in these cells was investigated in an in vitro dual-chamber model co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec8f1dbc5b7dc8ffa3d040995a96e2b
https://europepmc.org/articles/PMC114768/

Zobrazit plný text záznamu

The interaction of human fetal neurons and epidermal cells in vitro

Autor: Patricia J. Armati, Mark E. T. Penfold, Anthony L. Cunningham, Zorka Mikloska

Publikováno v: In vitro cellulardevelopmental biology. Animal. 32(7)

The interaction of autologous human fetal neurons with epidermal cells was studied by culturing fetal dorsal root ganglia (DRG) in the center of a dual chamber system with epidermal explants in the outer chamber. The two chambers were separated by tw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1cb9ae586ecfc6e8a6436782c7f2e00
https://pubmed.ncbi.nlm.nih.gov/8856342

Zobrazit plný text záznamu

Immunodominant epitopes in herpes simplex virus type 2 glycoprotein D are recognized by CD4 lymphocytes from both HSV-1 and HSV-2 seropositive subjects

Autor: Martine Denis, John Sidney, Katerina Lagios, N J Bodsworth, Robert Finlayson, Zorka Mikloska, Janette Taylor, Rajiv Khanna, Karen Byth-Wilson, Alessandro Sette, Min Kim, Anthony L. Cunningham, Heather Dunckley

Publikováno v: Scopus-Elsevier

In human recurrent cutaneous herpes simplex, there is a sequential infiltrate of CD4 and then CD8 lymphocytes into lesions. CD4 lymphocytes are the major producers of the key cytokine IFN-γ in lesions. They recognize mainly structural proteins and e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f5826cfde6b5a3aa6c843adf865028
http://www.scopus.com/inward/record.url?eid=2-s2.0-58749094126&partnerID=MN8TOARS

Zobrazit plný text záznamu

Monophosphoryl lipid A and QS21 increase CD8 T lymphocyte cytotoxicity to herpes simplex virus-2 infected cell proteins 4 and 27 through IFN-γ and IL-12 production

Autor: Martine Denis, Iraj Ghadiminejad, Heather Dunckley, Zorka Mikloska, Anthony L. Cunningham, Monica Rückholdt

Publikováno v: Scopus-Elsevier

We have shown previously that IFN-γ pretreatment of human epidermal cells (ECs) cultured in vitro partially reverses down-regulation of surface MHC class I by HSV infection, allowing recognition by CD8 CTLs, and that HSV immediate early (IE)/early (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc982cb4ca31d8168871868c0915198
http://www.scopus.com/inward/record.url?eid=2-s2.0-0343527202&partnerID=MN8TOARS

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání