Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Zorica, Janjetovic"'
Publikováno v:
Cosmetics, Vol 11, Iss 2, p 37 (2024)
Vitamin D is a natural photoproduct that has many beneficial effects on different organs, including skin. Active forms of vitamin D and its derivatives exert biological effects on skin cells, thus maintaining skin homeostasis. In keratinocytes, they
Externí odkaz:
https://doaj.org/article/19bcc4969a5a4bb0836a48bbf9290238
Autor:
Zorica Janjetovic, Shariq Qayyum, Sivani B. Reddy, Ewa Podgorska, S. Gates Scott, Justyna Szpotan, Alisa A. Mobley, Wei Li, Vijay K. Boda, Senthilkumar Ravichandran, Robert C. Tuckey, Anton M. Jetten, Andrzej T. Slominski
Publikováno v:
Cells, Vol 13, Iss 3, p 239 (2024)
We investigated multiple signaling pathways activated by CYP11A1-derived vitamin D3 hydroxymetabolites in human skin fibroblasts by assessing the actions of these molecules on their cognate receptors and by investigating the role of CYP27B1 in their
Externí odkaz:
https://doaj.org/article/49e273a96d6b44959945a696dfc09806
Autor:
Andrzej T. Slominski, Tae-Kang Kim, Radomir M. Slominski, Yuwei Song, Shariq Qayyum, Wojciech Placha, Zorica Janjetovic, Konrad Kleszczyński, Venkatram Atigadda, Yuhua Song, Chander Raman, Cornelis J. Elferink, Judith Varady Hobrath, Anton M. Jetten, Russel J. Reiter
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15496 (2023)
Melatonin is widely present in Nature. It has pleiotropic activities, in part mediated by interactions with high-affinity G-protein-coupled melatonin type 1 and 2 (MT1 and MT2) receptors or under extreme conditions, e.g., ischemia/reperfusion. In pha
Externí odkaz:
https://doaj.org/article/aedfc88a4e004f4881a92b6461ce04d9
Autor:
Andrzej T. Slominski, Tae-Kang Kim, Shariq Qayyum, Yuwei Song, Zorica Janjetovic, Allen S. W. Oak, Radomir M. Slominski, Chander Raman, Joanna Stefan, Carlos A. Mier-Aguilar, Venkatram Atigadda, David K. Crossman, Andriy Golub, Yaroslav Bilokin, Edith K. Y. Tang, Jake Y. Chen, Robert C. Tuckey, Anton M. Jetten, Yuhua Song
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-23 (2021)
Abstract The interactions of derivatives of lumisterol (L3) and vitamin D3 (D3) with liver X receptors (LXRs) were investigated. Molecular docking using crystal structures of the ligand binding domains (LBDs) of LXRα and β revealed high docking sco
Externí odkaz:
https://doaj.org/article/25793fb5b8704b48b8b033ea0ef380e3
Autor:
Georgeta Bocheva, Radomir M. Slominski, Zorica Janjetovic, Tae-Kang Kim, Markus Böhm, Kerstin Steinbrink, Russel J. Reiter, Konrad Kleszczyński, Andrzej T. Slominski
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1238 (2022)
The skin, being the largest organ in the human body, is exposed to the environment and suffers from both intrinsic and extrinsic aging factors. The skin aging process is characterized by several clinical features such as wrinkling, loss of elasticity
Externí odkaz:
https://doaj.org/article/3dec0c7c5c8243178a9f1345ef2ecb15
Autor:
Monica L. Brown Lobbins, Andrzej T. Slominski, Karen A. Hasty, Sicheng Zhang, Duane D. Miller, Wei Li, Tae-Kang Kim, Zorica Janjetovic, Robert C. Tuckey, Imara-Safi O. Scott, Linda K. Myers, Arnold E. Postlethwaite
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 367 (2021)
We previously demonstrated that the non-calcemic pregnacalciferol (pD) analog 17,20S (OH)2pD suppressed TGF-β1-induced type I collagen production in cultured normal human dermal fibroblasts. In the present studies, we examined fibroblasts cultured f
Externí odkaz:
https://doaj.org/article/c7bce4db2efe4d68b05ba81c56c86282
Autor:
Monica L. Brown Lobbins, Imara-Safi O. Scott, Andrzej T. Slominski, Karen A. Hasty, Sicheng Zhang, Duane D. Miller, Wei Li, Tae-Kang Kim, Zorica Janjetovic, Tejesh S. Patel, Linda K. Myers, Arnold E. Postlethwaite
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8926 (2021)
Systemic sclerosis (SSc; scleroderma) is a chronic fibrotic disease involving TGF-β1. Low serum vitamin D (vit D) correlates with the degree of fibrosis and expression of TGF-β1. This study was designed to determine whether the noncalcemic vit D an
Externí odkaz:
https://doaj.org/article/586caac290d64398abc0326b37197255
Autor:
Zorica Janjetovic, Stuart G. Jarrett, Elizabeth F. Lee, Cory Duprey, Russel J. Reiter, Andrzej T. Slominski
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Ultraviolet light (UV) is an inducer of reactive oxygen species (ROS) as well as 6-4-photoproducts and cyclobutane pyrimidine dimers (CPD) in the skin, which further cause damage to the skin cells. Irradiation of cultured human melanocytes w
Externí odkaz:
https://doaj.org/article/4ecbb7899b874c869da790e441ecfd5d
Autor:
Anyamanee Chaiprasongsuk, Zorica Janjetovic, Tae-Kang Kim, Stuart G. Jarrett, John A. D'Orazio, Michael F. Holick, Edith K.Y. Tang, Robert C. Tuckey, Uraiwan Panich, Wei Li, Andrzej T. Slominski
Publikováno v:
Redox Biology, Vol 24, Iss , Pp - (2019)
We tested whether novel CYP11A1-derived vitamin D3- and lumisterol-hydroxyderivatives, including 1,25(OH)2D3, 20(OH)D3, 1,20(OH)2D3, 20,23(OH)2D3, 1,20,23(OH)3D3, lumisterol, 20(OH)L3, 22(OH)L3, 20,22(OH)2L3, and 24(OH)L3, can protect against UVB-ind
Externí odkaz:
https://doaj.org/article/f0a5b634dfe44aa4bdf6e2e7a315bd20
Autor:
Joanna Stefan, Tae-Kang Kim, Fiona Schedel, Zorica Janjetovic, David K. Crossman, Kerstin Steinbrink, Radomir M. Slominski, Jaroslaw Zmijewski, Meri K. Tulic, Russel J. Reiter, Konrad Kleszczyński, Andrzej T. Slominski
Publikováno v:
Antioxidants, Vol 10, Iss 4, p 618 (2021)
We investigated the effects of melatonin and its selected metabolites, i.e., N1-Acetyl-N2-formyl-5-methoxykynurenamine (AFMK) and 6-hydroxymelatonin (6(OH)Mel), on cultured human epidermal keratinocytes (HEKs) to assess their homeostatic activities w
Externí odkaz:
https://doaj.org/article/8549b9de92ca4af5af33347ea3915b07