Výsledky vyhledávání

Computational fabrication of macromolecules to enhance perception and understanding of biological mechanisms

Autor: Alderighi T., Giorgi D., Malomo L., Cignoni P., Zoppè M.

Publikováno v: Smart Tools and Applications in Graphics (STAG) 2019, pp. 103–104, Cagliari, Italy, 14-15/11/2019
info:cnr-pdr/source/autori:Alderighi T.; Giorgi D.; Malomo L.; Cignoni P.; Zoppè M./congresso_nome:Smart Tools and Applications in Graphics (STAG) 2019/congresso_luogo:Cagliari, Italy/congresso_data:14-15%2F11%2F2019/anno:2019/pagina_da:103/pagina_a:104/intervallo_pagine:103–104

We propose a fabrication technique for the fast and cheap production of 3D replicas of proteins. We leverage silicone casting with rigid molds, to produce flexible models which can be safely extracted from the mold, and easily manipulated to simulate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43868cebdf3f8acdcf1236ecc74f6974
https://publications.cnr.it/doc/417187

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3D Chromatin structure estimation from chromosome conformation capture data

Autor: Caudai C., Salerno E., Zoppè M., Tonazzini A.

Publikováno v: BITS 2017-14th Annual Meeting of the Bioinformatics Italian Society, Cagliari, Italy, 5-7 July 2017
info:cnr-pdr/source/autori:Caudai C.; Salerno E.; Zoppè M.; Tonazzini A./congresso_nome:BITS 2017-14th Annual Meeting of the Bioinformatics Italian Society/congresso_luogo:Cagliari, Italy/congresso_data:5-7 July 2017/anno:2017/pagina_da:/pagina_a:/intervallo_pagine

In this communication we describe ChromStruct4, a method to reconstruct a set of plausible chromatin configurations starting from contact data obtained through Chromosome Conformation Capture techniques. Chromating fibre is modeled as a kinematic cha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::24efc2a6a61cf4aea4e0bfdbfd5a3fa9
https://openportal.isti.cnr.it/doc?id=people______::24efc2a6a61cf4aea4e0bfdbfd5a3fa9

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Consistency tests for a recursive multi-scale 3D chromatin structure reconstruction algorithm

Autor: Caudai C., Salerno E., Zoppè M., Tonazzini A.

Publikováno v: Project report, InterOmic, 2016

In this report, we test the consistency and coherence of an algorithm obtained as an extension of a technique we proposed in the past. This implements a recursive multi-scale reconstruction of the 3d chromatin structure from Chromosome Conformation C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5201d8039b1aa9d512a19f1a42817cb2
https://openportal.isti.cnr.it/doc?id=people______::5201d8039b1aa9d512a19f1a42817cb2

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Protein molecular dynamics using quaternions and Monte Carlo methods

Autor: Caudai C., Zoppè M., Pascali M. A., Salerno E., Tonazzini A.

Publikováno v: Quinta Edizione della Giornata Toscana di Bioinformatica e Systems Biology, Firenze, Italy, 28 ottobre 2016
info:cnr-pdr/source/autori:Caudai C.; Zoppè M.; Pascali M. A.; Salerno E.; Tonazzini A./congresso_nome:Quinta Edizione della Giornata Toscana di Bioinformatica e Systems Biology/congresso_luogo:Firenze, Italy/congresso_data:28 ottobre 2016/anno:2016/pagina_da:/pagina_a:/intervallo_pagine

We present a new approach to molecular dynamics (MD) of proteins based on Monte Carlo Methods applied to atomic 3D models managed by quaternions. Classical MD simulations provide detailed information on the conformational changes of proteins and nucl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d12dcbb463c0376c13868293739fbdbc
http://www.cnr.it/prodotto/i/360515

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3D chromatin structure estimation through a constraint-enhanced score function

Autor: Caudai C., Salerno E., Zoppè M., Tonazzini A.

Publikováno v: ISTI Working papers, 2016

Based on experimental techniques of the type Chromosome Conformation Capture (3c), several methods have been proposed in the literature to estimate the structure of the nuclear dna in homogeneous populations of cells. Many of these methods transform

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::edb87b3133c51114dbf36769e498f577
http://www.cnr.it/prodotto/i/385603

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InterOmics - Reconstructing 3D chromatin structure from chromosome conformation capture data

Autor: Caudai C., Salerno E., Zoppè M., Tonazzini A.

Publikováno v: Project report, InterOmics, 2015

Dna is the central repository of information to keep cells and organisms alive. In human cells, the 46 chromosomes amount to a length of about 2 m, with a diameter of 2 nm, and are packed in a way that allows for access by transcription, replication

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::467b74873b9f0b1ca8a8ff4825995359
https://openportal.isti.cnr.it/doc?id=people______::467b74873b9f0b1ca8a8ff4825995359

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A multiscale model for 3D chromatin structure estimation using quaternions

Autor: Caudai C., Salerno E., Zoppè M., Tonazzini A.

Publikováno v: ECCB 2014-13th European Conference on Computational Biology, Strasbourg, France, 7-10 September 2014
info:cnr-pdr/source/autori:Caudai C.; Salerno E.; Zoppè M.; Tonazzini A./congresso_nome:ECCB 2014-13th European Conference on Computational Biology/congresso_luogo:Strasbourg, France/congresso_data:7-10 September 2014/anno:2014/pagina_da:/pagina_a:/intervallo_pagine

We present a method to reconstruct a set of plausible chromatin configurations from contact data obtained through Chromosome Conformation Capture techniques. We do not look for a unique configuration because the experimental data are not derived from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::83782b415e17b9bcb7cc77a0a513aae4
http://www.cnr.it/prodotto/i/305488

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