Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for β-Cell Function During Aging.

Autor: Ortiz JA; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA.; Irell and Manella School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA., Ghazalli N; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA.; Irell and Manella School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA., Lopez K; Irell and Manella School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA., Rawson J; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA., McCown EM; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA., Oh E; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA., Irimia JM; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA.; Comprehensive Metabolic Phenotyping Core, City of Hope, Duarte, CA., Jou K; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA., Mares J; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA., Chen MH; Integrative Genomics Core, City of Hope, Duarte, CA., Wu X; Comprehensive Metabolic Phenotyping Core, City of Hope, Duarte, CA., Zook HN; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA.; Irell and Manella School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA., Quijano JC; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA., Erdem N; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA.; Irell and Manella School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA., Lizarraga A; Eugene and Ruth Roberts Summer Student Academy, City of Hope, Duarte, CA., Kandeel F; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA., Fueger PT; Irell and Manella School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA.; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA.; Comprehensive Metabolic Phenotyping Core, City of Hope, Duarte, CA., Thurmond DC; Irell and Manella School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA.; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA., Ku HT; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA.; Irell and Manella School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA.

Publikováno v: Diabetes [Diabetes] 2024 Sep 01; Vol. 73 (9), pp. 1447-1461.

Activation of ductal progenitor-like cells from adult human pancreas requires extracellular matrix protein signaling.

Autor: Zook HN; Irell & Manella Graduate School of Biological Sciences, City of Hope National Medical Center, Duarte, CA 91010, USA.; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA., Quijano JC; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA., Ortiz JA; Irell & Manella Graduate School of Biological Sciences, City of Hope National Medical Center, Duarte, CA 91010, USA.; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA., Donohue C; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA., Lopez K; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA., Li W; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA., Erdem N; Irell & Manella Graduate School of Biological Sciences, City of Hope National Medical Center, Duarte, CA 91010, USA.; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA.; Department of Diabetes Immunology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA., Jou K; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA., Crook CJ; Irell & Manella Graduate School of Biological Sciences, City of Hope National Medical Center, Duarte, CA 91010, USA.; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA., Garcia I Jr; Department of Diabetes Immunology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA., Kandeel F; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA., Montero E; Department of Diabetes Immunology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA., Ku HT; Irell & Manella Graduate School of Biological Sciences, City of Hope National Medical Center, Duarte, CA 91010, USA.; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA.

Publikováno v: IScience [iScience] 2024 Feb 15; Vol. 27 (3), pp. 109237. Date of Electronic Publication: 2024 Feb 15 (Print Publication: 2024).

A matrigel-free method for culture of pancreatic endocrine-like cells in defined protein-based hydrogels.

Autor: Kozlowski MT; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, United States., Zook HN; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA, United States.; The Irell and Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA, United States., Chigumba DN; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, United States., Johnstone CP; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, United States., Caldera LF; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, United States., Shih HP; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA, United States.; The Irell and Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA, United States., Tirrell DA; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, United States., Ku HT; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA, United States.; The Irell and Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA, United States.

Publikováno v: Frontiers in bioengineering and biotechnology [Front Bioeng Biotechnol] 2023 Mar 09; Vol. 11, pp. 1144209. Date of Electronic Publication: 2023 Mar 09 (Print Publication: 2023).