Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Zongzhi, Liu"'
Autor:
Ting Zhang, Wenjing Rui, Yue Sun, Yunyun Tian, Qiaoyan Li, Qian Zhang, Yanchun Zhao, Zongzhi Liu, Tiepeng Wang
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-18 (2024)
Abstract Parkinson's disease (PD) involves multiple forms of neuronal cell death, but the dominant pathway involved in disease progression remains unclear. This study employed RNA sequencing (RNA-seq) of brain tissue to explore gene expression patter
Externí odkaz:
https://doaj.org/article/f64e84197b6c44c5b9ffbdba9e4200a0
Autor:
Zongzhi Liu, Xiang Li, Yibo Gao, Jiejie Liu, Yating Feng, Yang Liu, Junyun Wang, Chunmeng Wang, Dongrui Wang, Jie He, Weidong Han, Qian Mei, Yingli Sun
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract Background Checkpoint blockade immunotherapy, represented by PD-1 or PD-L1 antibody treatment, has been of tremendous success in clinical practice. However, the low clinical response rate and lack of biomarkers for prediction of the immune r
Externí odkaz:
https://doaj.org/article/be4dd20a747248ef99d4a24c94a18e20
Autor:
Kyeryoung Lee, Zongzhi Liu, Urmila Chandran, Iftekhar Kalsekar, Balaji Laxmanan, Mitchell K Higashi, Tomi Jun, Meng Ma, Minghao Li, Yun Mai, Christopher Gilman, Tongyu Wang, Lei Ai, Parag Aggarwal, Qi Pan, William Oh, Gustavo Stolovitzky, Eric Schadt, Xiaoyan Wang
Publikováno v:
JMIR AI, Vol 2, p e44537 (2023)
BackgroundGround-glass opacities (GGOs) appearing in computed tomography (CT) scans may indicate potential lung malignancy. Proper management of GGOs based on their features can prevent the development of lung cancer. Electronic health records are ri
Externí odkaz:
https://doaj.org/article/c8dc59e8dfdf409d87901daf54c1b1e0
Autor:
Zongzhi Liu, Xiang Gao, Chuanwen Kan, Lingyu Li, Yuan Zhang, Yibo Gao, Shengyuan Zhang, Liangji Zhou, Hui Zhao, Mingkun Li, Zheng Zhang, Yingli Sun
Publikováno v:
MedComm, Vol 4, Iss 1, Pp n/a-n/a (2023)
Abstract The recent pandemic of variants of concern (VOC) of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) highlights the need for innovative anti‐SARS‐CoV‐2 approaches in addition to vaccines and antiviral therapeutics. Here
Externí odkaz:
https://doaj.org/article/2a1357af2c0f4ea78a4d2a9866d20083
Publikováno v:
MedComm, Vol 3, Iss 3, Pp n/a-n/a (2022)
Abstract The changes in circulating tumor DNA (ctDNA) methylation are believed to be early events in breast cancer initiation, which makes them suitable as promising biomarkers for early diagnosis. However, applying ctDNA in breast cancer early diagn
Externí odkaz:
https://doaj.org/article/5ea22e15172e4256bea21b97b068396b
Autor:
Yibo Gao, Hengqiang Zhao, Ke An, Zongzhi Liu, Luo Hai, Renda Li, Yang Zhou, Weipeng Zhao, Yongsheng Jia, Nan Wu, Lingyu Li, Jianming Ying, Jie Wang, Binghe Xu, Zhihong Wu, Zhongsheng Tong, Jie He, Yingli Sun
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 8, Pp n/a-n/a (2022)
Abstract Background Cancer cell–specific variation and circulating tumour DNA (ctDNA) methylation are promising biomarkers for non‐invasive cancer detection and molecular classification. Nevertheless, the applications of ctDNA to the early detect
Externí odkaz:
https://doaj.org/article/9f392c020e4442298e8f0b07dcd33fbc
Autor:
Yao Wang, Chuan Tong, Hanren Dai, Zhiqiang Wu, Xiao Han, Yelei Guo, Deyun Chen, Jianshu Wei, Dongdong Ti, Zongzhi Liu, Qian Mei, Xiang Li, Liang Dong, Jing Nie, Yajing Zhang, Weidong Han
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
De novo DNA methylation has been associated with T cell exhaustion in cancer immunotherapy. Here the authors show that the pre-treatment of CD19 CAR-T cells with the DNA methyltransferase inhibitor decitabine limits exhaustion and confers enhanced pr
Externí odkaz:
https://doaj.org/article/933c244786634cf58dfafd51abcccf81
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundPseudohypoaldosteronism (PHA) diseases are difficult to diagnose because symptoms are often non-specific and an in-depth pathogenesis study is still lacking.Case PresentationWe present the case of a 19-day-old neonate who presented with une
Externí odkaz:
https://doaj.org/article/522f7dca6dc94ccc83282ab86c2f2732
Autor:
Zongzhi Liu, Wei Chen, Zilong Zhang, Junyun Wang, Yi-Kun Yang, Luo Hai, Yuan Wei, Jie Qiao, Yingli Sun
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The DNA methylation of human offspring can change due to the use of assisted reproductive technology (ART). In order to find the differentially methylated regions (DMRs) in ART newborns, cord blood maternal cell contamination and parent DNA methylati
Externí odkaz:
https://doaj.org/article/6a044cb2149c420d952888d386b0db87
Autor:
Deborah Ayeni, Braden Miller, Alexandra Kuhlmann, Ping-Chih Ho, Camila Robles-Oteiza, Mmaserame Gaefele, Stellar Levy, Fernando J. de Miguel, Curtis Perry, Tianxia Guan, Gerald Krystal, William Lockwood, Daniel Zelterman, Robert Homer, Zongzhi Liu, Susan Kaech, Katerina Politi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Background Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibitors (TKIs) like erlotinib are effective for treating patients with EGFR mutant lung cancer; however, drug resistance inevitably emerges. Approaches to combine immunoth
Externí odkaz:
https://doaj.org/article/747919cbf484433eaa47ef5535f2fc44