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pro vyhledávání: '"Zongyao Lv"'
Autor:
Lulu Guo, Yumu Zhang, Guoxing Fang, Lu Tie, Yuming Zhuang, Chenyang Xue, Qi Liu, Minghui Zhang, Kongkai Zhu, Chongzhao You, Peiyu Xu, Qingning Yuan, Chao Zhang, Lei Liu, Naikang Rong, Shengxuan Peng, Yuan Liu, Chuanzheng Wang, Xin Luo, Zongyao Lv, Dongwei Kang, Xiao Yu, Cheng Zhang, Yi Jiang, Xinzhong Dong, Jiuyao Zhou, Zhongmin Liu, Fan Yang, H. Eric Xu, Jin-Peng Sun
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract MRGPRX1, a Mas-related GPCR (MRGPR), is a key receptor for itch perception and targeting MRGPRX1 may have potential to treat both chronic itch and pain. Here we report cryo-EM structures of the MRGPRX1-Gi1 and MRGPRX1-Gq trimers in complex w
Externí odkaz:
https://doaj.org/article/760d907008f24e78b84b2534b10f2648