Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Zongshu Luo"'
Autor:
Jon M Carthy, Anna J Meredith, Seti Boroomand, Thomas Abraham, Zongshu Luo, Darryl Knight, Bruce M McManus
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133056 (2015)
Versican, a chondroitin sulphate proteoglycan, is one of the key components of the provisional extracellular matrix expressed after injury. The current study evaluated the hypothesis that a versican-rich matrix alters the phenotype of cultured fibrob
Externí odkaz:
https://doaj.org/article/09f5489d3f234a76a530fc068b1c5507
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128655 (2015)
Epidemiological and interventional studies have suggested a protective role for vitamin D in cardiovascular disease, and basic research has implicated vitamin D as a potential inhibitor of fibrosis in a number of organ systems; yet little is known re
Externí odkaz:
https://doaj.org/article/48e93de5a2a64b3c8918f3a8d032a7a2
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19809 (2011)
Growing evidence suggests the Wnt family of secreted glycoproteins and their associated signaling pathways, linked to development, are recapitulated during wound repair and regeneration events. However, the role of the Wnt pathway in such settings re
Externí odkaz:
https://doaj.org/article/5df09038b05649d1acf8442d1795f20c
Autor:
Kamran Shojania, J Antonio Aviña-Zubieta, Kevin Rey, Zongshu Luo, Winnie Enns, Michael A. Seidman, Sukhbir Manku, Jonathan C. Choy, Wendy Wong, Zainab Alabdurubalnabi
Publikováno v:
Cardiovascular Pathology. 33:55-61
Giant cell arteritis (GCA) is the most common vasculitis in adults affecting large and medium-sized arteries. IL-6 and T cell accumulation within the arterial wall contribute to the pathogenesis of GCA, and blockade of IL-6 activity is efficacious in
Autor:
Karin Jensen, Jun Lin, Zongshu Luo, Kevin A. Janes, Decheng Yang, Farshid S. Garmaroudi, Seti Boroomand, Mary Zhang, Jingchun Zhang, Honglin Luo, Bruce M. McManus
Publikováno v:
Cell Host & Microbe. 13(1):67-76
Summary The host response to a virus is determined by intracellular signaling pathways that are modified during infection. These pathways converge as networks and produce interdependent phenotypes, making it difficult to link virus-induced signals an
Publikováno v:
Laboratory Investigation. 92:246-255
Evidence suggests a role for Wnt signaling in vascular wound repair and remodeling events. Despite this, very little is known about the effect of Wnt ligands on the structure and function of vascular cells. In this study, we treated vascular smooth m
Autor:
Bobby Yanagawa, Bruce M. McManus, Zongshu Luo, Jiang Chang, Xiangsheng Yang, Jingchun Zhang, Honglin Luo, Jerry Wong
Publikováno v:
Cell Research. 22:360-371
Enteroviral infection can lead to dilated cardiomyopathy (DCM), which is a major cause of cardiovascular mortality worldwide. However, the pathogenetic mechanisms have not been fully elucidated. Serum response factor (SRF) is a cardiac-enriched trans
Autor:
Donald Wong, Maziar Rahmani, Honglin Luo, Bruce M. McManus, Zongshu Luo, Brian W. Wong, Bobby Yanagawa
Publikováno v:
The Journal of Heart and Lung Transplantation. 28:950-957
Background Endothelial cell hyperpermeability is a proposed mechanism of increased lipid insudation into the vessel walls of allografts. Vascular endothelial growth factor (VEGF) is a potent inducer of vascular permeability and its expression is upre
Autor:
Elizabeth K.-Y. Walker, Robert M. Senior, Christopher M. Overall, Bruce M. McManus, David J. Marchant, Caroline Cheung, Jingchun Zhang, Maziar Rahmani, Zongshu Luo, Bobby Yanagawa, Jennifer H. Cox, Honglin Luo
Publikováno v:
Circulation. 117:1574-1582
Background—Coxsackievirus B3 (CVB3) causes human myocarditis, which can result in cardiac damage, maladaptive remodeling, and heart failure. Matrix metalloproteinases (MMP)-8 and -9 have been identified in virus-infected myocardium, but their parti
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128655 (2015)
PLoS ONE
PLoS ONE
Aims Epidemiological and interventional studies have suggested a protective role for vitamin D in cardiovascular disease, and basic research has implicated vitamin D as a potential inhibitor of fibrosis in a number of organ systems; yet little is kno