Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Zongren Zhao"'
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
BackgroundTraumatic brain injury (TBI) causes neuronal cell damage and dysfunction. According to previous studies, daphnetin (Dap) has a protective effect in neurological injury. However, the in vivo bioavailability of daphnetin is not high. The purp
Externí odkaz:
https://doaj.org/article/891e501c84774260b90bd2e7d1e7bf5c
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Glioma is considered one of the most lethal brain tumors, as the aggressive blood vessel formation leads to high morbidity and mortality rates. However, the mechanisms underlying the initiation and progression of glioma remain unclear. Here, we aimed
Externí odkaz:
https://doaj.org/article/ddb8f992df7f4726bfdac95994941a4a
Autor:
Zhenkun Zong, Lei Hua, Zhen Wang, Haoyue Xu, Chengkun Ye, Bomin Pan, Zongren Zhao, Longzhen Zhang, Jun Lu, Hongmei Liu, Rutong Yu
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 34-44 (2019)
The addition of temozolomide (TMZ) to radiotherapy (RT) improves survival of patients with glioblastoma (GBM). However, TMZ + RT causes excess toxicity in patients. In this study, we prepared angiopep-2 (A2) modified lipid-poly (hypoxic radiosensitiz
Externí odkaz:
https://doaj.org/article/55ea6a0ac5d74a18aebc2e819ffa841b
Background: CTSS(Cathepsisn S) is a lysosomal cysteine protease which is found in many tissues and plays multifarious roles. However, the role of CTSS in tumorigenesis is poorly defined. We investigated the association between CTSS levels and prognos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2374220da4d07e0f775b910afaf0a32a
https://doi.org/10.21203/rs.3.rs-2876916/v1
https://doi.org/10.21203/rs.3.rs-2876916/v1
Autor:
Rutong Yu, Zhen Wang, Jun Lu, Zongren Zhao, Yuhan Han, Liang Zhao, Konduru Naveena, Hongmei Liu, Gang Zhao, Long Zhang, Lei Hua, Haoyue Xu
Publikováno v:
ACS Applied Materials & Interfaces. 12:52319-52328
Glioma is the most prevalent type of malignant brain tumor and is usually very aggressive. Because of the high invasiveness and aggressive proliferative growth of glioma, it is difficult to resect completely or cure with surgery. Residual glioma cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7500a7de6e49ccabf669062a5d4a234a
https://doi.org/10.1021/acsami.0c12971
https://doi.org/10.1021/acsami.0c12971
Autor:
Jun Lu, Zongren Zhao, Dong-Mei Wu, Hongmei Liu, Hui Shi, Zhengzhong Han, Yu Rutong, Jun Jia, Haoyue Xu, Shuo Sun
Publikováno v:
International Journal of Nanomedicine. 15:3347-3362
Introduction Temozolomide (TMZ) is the first-line chemotherapeutic option to treat glioma; however, its efficacy and clinical application are limited by its drug resistance properties. Polo-like kinase 1 (PLK1)-targeted therapy causes G2/M arrest and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66955d9b2409ff6ca0bd09d1e33f0f02
https://doi.org/10.2147/ijn.s243878
https://doi.org/10.2147/ijn.s243878
Publikováno v:
Journal of Molecular Medicine. 97:1575-1588
Glioblastoma is one of the most aggressive types of brain tumor. Epidermal growth factor receptors (EGFRs) are overexpressed in glioma, and EGFR amplifications and mutations lead to rapid proliferation and invasion. EGFR-targeted therapy might be an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8aba2036525a3ad95dbfdffc8983aa9
https://doi.org/10.1007/s00109-019-01843-4
https://doi.org/10.1007/s00109-019-01843-4
Autor:
Zongren Zhao, Jiawei Shen, Long Zhang, Lansheng Wang, Haoyue Xu, Yuhan Han, Jun Jia, Yang Lu, Rutong Yu, Hongmei Liu
Publikováno v:
Biomaterials science. 8(19)
Glioma is the most aggressive primary malignant brain tumor. The eradication of the gliomas by performing neurosurgery has not been successful due to the diffuse nature of malignant gliomas. Temozolomide (TMZ) is the first-line agent in treating glio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedcdc83e2e1121a77f9c3fdec2f1799
https://pubmed.ncbi.nlm.nih.gov/33570070
https://pubmed.ncbi.nlm.nih.gov/33570070
Autor:
Hui, Shi, Shuo, Sun, Haoyue, Xu, Zongren, Zhao, Zhengzhong, Han, Jun, Jia, Dongmei, Wu, Jun, Lu, Hongmei, Liu, Rutong, Yu
Publikováno v:
International Journal of Nanomedicine
Introduction Temozolomide (TMZ) is the first-line chemotherapeutic option to treat glioma; however, its efficacy and clinical application are limited by its drug resistance properties. Polo-like kinase 1 (PLK1)-targeted therapy causes G2/M arrest and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec6c6a9b4ad6a5d311108ed64b8c8f2f
https://pubmed.ncbi.nlm.nih.gov/32494134
https://pubmed.ncbi.nlm.nih.gov/32494134
Autor:
Shun Li, Haoyue Xu, Deyun Zhang, Hongmei Liu, Zongren Zhao, Longzhen Zhang, Yuhan Han, Zhengzhong Han, Jun Jia, Yu Rutong
Publikováno v:
Journal of biomedical nanotechnology. 15(9)
Radiotherapy (RT) has become one of the most effective treatments for malignant tumor. Intra-tumoral hypoxia is recognized as a chief reason that induces resistance to radiation. Moreover, the toxicities of RT to normal tissues limits the usage of hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcfca428bdd91144f11930838345a96
https://pubmed.ncbi.nlm.nih.gov/31387684
https://pubmed.ncbi.nlm.nih.gov/31387684