Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Zongren Xu"'
Single‐cell RNA sequencing reveals inflammatory retinal microglia in experimental autoimmune uveitis
Autor:
Jiangyi Liu, Xingyun Liao, Na Li, Zongren Xu, Wang Yang, Hongxiu Zhou, Yusen Liu, Zhi Zhang, Guoqing Wang, Shengping Hou
Publikováno v:
MedComm, Vol 5, Iss 4, Pp n/a-n/a (2024)
Abstract Autoimmune uveitis (AU) is a kind of immune‐mediated disease resulting in irreversible ocular damage and even permanent vision loss. However, the precise mechanism underlying dynamic immune changes contributing to disease initiation and pr
Externí odkaz:
https://doaj.org/article/950c88ce32a247dba87b0802384468f3
Autor:
Ruonan Li, Jiangyi Liu, Ping Yi, Xianli Yang, Jun Chen, Chenyang Zhao, Xingyun Liao, Xiaotang Wang, Zongren Xu, Huiping Lu, Hongshun Li, Zhi Zhang, Xianyang Liu, Junjie Xiang, Ke Hu, Hongbo Qi, Jia Yu, Peizeng Yang, Shengping Hou
Publikováno v:
Advanced Science, Vol 10, Iss 16, Pp n/a-n/a (2023)
Abstract The underlying mechanisms that determine gene expression and chromatin accessibility in retinogenesis are poorly understood. Herein, single‐cell RNA sequencing and single‐cell assay for transposase‐accessible chromatin sequencing are p
Externí odkaz:
https://doaj.org/article/0fea79c6beef4fe595dd614cfcdbf338
Autor:
Xiaotang Wang, Wei Fan, Zongren Xu, Qi Zhang, Na Li, Ruonan Li, Guoqing Wang, Siyuan He, Wanqian Li, Dan Liao, Zhi Zhang, Nan Shu, Jiaxing Huang, Chenyang Zhao, Shengping Hou
Publikováno v:
MedComm, Vol 4, Iss 1, Pp n/a-n/a (2023)
Abstract Stem cell therapy is a promising strategy to rescue visual impairment caused by retinal degeneration. Previous studies have proposed controversial theories about whether in situ retinal stem cells (RSCs) are present in adult human eye tissue
Externí odkaz:
https://doaj.org/article/8e4817675269478889352424604ed336
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The N6-methyladenosine (m6A) modification is the most abundant posttranscriptional mRNA modification in mammalian cells and is dynamically modulated by a series of “writers,” “erasers,” and “readers.” Studies have shown that m6A affects R
Externí odkaz:
https://doaj.org/article/3f1308f1dc6d492488df4426b9d88eb0
Autor:
Zongren Xu, Xingyun Liao, Na Li, Hongxiu Zhou, Hong Li, Qi Zhang, Ke Hu, Peizeng Yang, Shengping Hou
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Human retinal pigment epithelium cells are arranged in a monolayer that plays an important supporting role in the retina. Although the heterogeneity of specific retinal cells has been well studied, the diversity of hRPE cells has not been reported. H
Externí odkaz:
https://doaj.org/article/67d5243c00c944d9bbae21b795c1fbc0
Background Liver cancer is one of the most common causes of cancer-related death and is quantitatively dominated by the liver hepatocellular carcinoma (HCC) subtype. Although advances have been made in recent years, further exploration on new HCC car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::233fa0eb65ce46cba2fd637a13e2c581
https://doi.org/10.21203/rs.3.rs-1461119/v2
https://doi.org/10.21203/rs.3.rs-1461119/v2
Liver cancer is one of the most common causes of cancer-related death and is quantitatively dominated by the liver hepatocellular carcinoma (HCC) subtype. Although advances have been made in recent years, further exploration on new HCC carcinogenic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02e2bb64727e5aae29d5daf2c820c746
https://doi.org/10.21203/rs.3.rs-1461119/v1
https://doi.org/10.21203/rs.3.rs-1461119/v1
Autor:
Qinjin Dai, Jing Xu, Shengping Hou, Suyin Mei, Zongren Xu, Aize Kijlstra, Yike Huang, Juan Wu, Na Li, Peizeng Yang
Publikováno v:
Current Molecular Medicine, 20(8), 624-632. Bentham Science Publishers Ltd.
Purpose: A small molecular compound, aminooxy-acetic acid (AOA), has been shown to modulate experimental autoimmune encephalomyelitis (EAE). The current study was designed to investigate whether AOA has a similar effect on the development of experime
Autor:
Xianyang Liu, Jiayu Meng, Xingyun Liao, Yusen Liu, Chenyang Zhao, Zongren Xu, Guanan Su, Siyuan He, Wanqian Li, Xiaotang Wang, Guoqing Wang, Qian Zhou, Peizeng Yang, Shengping Hou
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Clinical immunology (Orlando, Fla.). 236
Galectin-3, an attractive molecule of innate immunity, has been reported to be involved in the neuroinflammatory diseases. However, the role of Galectin-3 in autoimmune uveitis is still unclear. The purpose of this study was to investigate the effect