Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Zongqin Xia"'
Autor:
Zongqin Xiang, Shu He, Rongjie Chen, Shanggong Liu, Minhui Liu, Liang Xu, Jiajun Zheng, Zhouquan Jiang, Long Ma, Ying Sun, Yongpeng Qin, Yi Chen, Wen Li, Xiangyu Wang, Gong Chen, Wenliang Lei
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 8, Pp 1781-1788 (2024)
Over the past decade, a growing number of studies have reported transcription factor-based in situ reprogramming that can directly convert endogenous glial cells into functional neurons as an alternative approach for neuroregeneration in the adult ma
Externí odkaz:
https://doaj.org/article/ab77e5342b5645589834b7c4b910ec6b
Publikováno v:
Brain Research. 1441:27-37
Our previous studies demonstrate that a non-cholinesterase inhibitor (AChEI) compound catalpol, purified from a traditional Chinese medicinal herb Rehmannia glutinosa, could improve the symptoms and pathological changes in animal and cellular models
Publikováno v:
Neurobiology of Aging. 31:1010-1019
The purpose of this work is to study the effect of smilagenin on the mRNA stability of muscarinic receptor subtype 1 (M(1); m1 mRNA) in aged rat brains and its significance in improving memory. The Y-maze avoidance task showed that oral administratio
Publikováno v:
Neuroscience. 167:174-184
The protective effect of an iridoid catalpol extracted and purified from the traditional Chinese medicinal herb Rehmannia glutinosa on the neuronal degeneration of nigral-striatal dopaminergic pathway was studied in a chronic 1-methyl-4-phenyl-1,2,3,
Publikováno v:
FEBS Letters. 582:956-960
Tyrosine hydroxylase immunohistochemical analysis revealed that in cultured mesencephalic dopaminergic neurons smilagenin (SMI), added prior to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPP+), protected against the drop of neuron number and neuri
Autor:
Weixiong Jiang, Erxi Wu, Junmin Li, R. Zhang, Yongfang Zhang, Zongqin Xia, X. Wang, Xuebing Ding, Xuejun Sun, Yaer Hu
Publikováno v:
Neuroscience. 303
So far, no effective disease-modifying therapies for Alzheimer's disease (AD) aiming at protecting or reversing neurodegeneration of the disease have been established yet. The present work aims to elucidate the effect of Harpagoside (abbreviated HAR)
Autor:
Xin Su, Shuxian Yang, Yanxiang Li, Zongqin Xiang, Qiao Tao, Shengde Liu, Zhinan Yin, Liyun Zhong, Xiaoxu Lv, Libing Zhou
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCerebral microbleeds (CMBs) are an early sign of many neurological disorders and accompanied by local neuroinflammation and brain damage. As important regulators of immune response and neuroinflammation, the biological behavior and role of
Externí odkaz:
https://doaj.org/article/9a2cc8d4c19748dd9eaa986463ab9477
Autor:
Zongqin Xia, Jiamei Li, Xiong Zhongkui, Xiaoyu Sun, Gang Xu, Yongfang Zhang, Zun-Ji Ke, Rui Zhang, Zhiming Xia, Yaer Hu, Ya Meng
Publikováno v:
Journal of Neurochemistry.
Parkinson's disease is a chronic neurodegenerative movement disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. New therapeutic approaches aiming at delaying or reversing the neurodegenerative process are
Autor:
Xiaoyu, Sun, Zhongkui, Xiong, Yongfang, Zhang, Ya, Meng, Gang, Xu, Zhiming, Xia, Jiamei, Li, Rui, Zhang, Zunji, Ke, Zongqin, Xia, Yaer, Hu
Publikováno v:
Journal of neurochemistry. 120(6)
Parkinson's disease is a chronic neurodegenerative movement disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. New therapeutic approaches aiming at delaying or reversing the neurodegenerative process are
Publikováno v:
Neuroscience. 163(4)
The purpose of this work is to study the effect of catalpol, an iridoid from Rehmannia glutinosa on neurodegenerative changes induced by beta-amyloid peptide Abeta(25-35) or Abeta(25-35)+ibotenic acid and the underlying mechanism. Results showed that