Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Zongqiang Wang"'
Autor:
Vincent Libis, Logan W. MacIntyre, Rabia Mehmood, Liliana Guerrero, Melinda A. Ternei, Niv Antonovsky, Ján Burian, Zongqiang Wang, Sean F. Brady
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Efficient mobilization and expression of biosynthetic gene clusters (BGCs) into heterologous hosts is needed for microbial natural products discovery. Here, the authors improve the CONKAT-seq strategy by simultaneously capturing the BCGs into a singl
Externí odkaz:
https://doaj.org/article/bf50f0e3f20d48b3a29e45a4676ef6ac
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Chemical synthesis of secondary metabolites isolated from nature, and derivatives thereof, is still a paradigm of significance to drug development. Here the authors instead use bioinformatics to analyze a biosynthetic gene cluster found in the soil m
Externí odkaz:
https://doaj.org/article/907f3ef3a9824f6891e0f4fae08900a7
Publikováno v:
mSystems, Vol 5, Iss 6 (2020)
ABSTRACT Polyketides (PKs) and nonribosomal peptides (NRPs) are two microbial secondary metabolite (SM) families known for their variety of functions, including antimicrobials, siderophores, and others. Despite their involvement in bacterium-bacteriu
Externí odkaz:
https://doaj.org/article/982dd7d256ca474c85fc630549087465
Autor:
Yuguang Zhao, Wenjing Song, Zhenyu Wang, Zongqiang Wang, Xing Jin, Jiancheng Xu, Ling Bai, Yuying Li, Jiuwei Cui, Lu Cai
Publikováno v:
Redox Biology, Vol 14, Iss , Pp 609-617 (2018)
Infertility is a common complication in diabetic men, mainly due to the loss of germ cells by apoptotic cell death. However, effective and safe approaches to prevent diabetic induction of testicular apoptosis for diabetic patients have not been avail
Externí odkaz:
https://doaj.org/article/d28c92639a684a0197d0bf6edfe86983
Autor:
Zongqiang Wang1, Koirala, Bimal1, Hernandez, Yozen1, Zimmerman, Matthew2, Brady, Sean F.1 sbrady@rockefeller.edu
Publikováno v:
Science. 5/27/2022, Vol. 376 Issue 6596, p991-996. 6p. 4 Diagrams, 1 Chart.
Publikováno v:
Chinese Journal of Aeronautics. 35:408-418
With the improvement of the accuracy of the inertial system, the influence of the disturbing gravity field on the accuracy of long-range rocket has become increasingly prominent. However, in actual engineering, there are problems of low accuracy and
Autor:
ZongQiang Wang, ZhaoGuo He, Qinghua Zhou, Fuliang Xiao, Sai Zhang, Yihua He, YanQiong Xie, C. Yang, Si Liu
Publikováno v:
Science China Technological Sciences. 65:131-138
Electromagnetic ion cyclotron (EMIC) emission is an efficient mechanism for scattering loss of energetic protons. Here, we report an event that provides both in-situ observation of energetic proton differential fluxes in the inner magnetosphere and p
Autor:
Melinda A. Ternei, Zongqiang Wang, Rabia Mehmood, Amanda Kasper, Sean F. Brady, Shao-Gang Li, Joel S. Freundlich
Publikováno v:
Angew Chem Int Ed Engl
Natural products are a major source of new antibiotics. Here we utilize biosynthetic instructions contained within metagenome-derived congener biosynthetic gene clusters (BGCs) to guide the synthesis of improved antibiotic analogues. Albicidin and cy
Publikováno v:
Organic letters. 24(27)
Cationic nonribosomal lipopeptides (CNRLPs) from
Autor:
Zongqiang Wang, Bimal Koirala, Yozen Hernandez, Matthew Zimmerman, Steven Park, David S. Perlin, Sean F. Brady
Publikováno v:
Nature
Gram-negative bacteria are responsible for an increasing number of deaths from antibiotic resistant infections.(1,2) The bacterial natural product, colistin, is considered the last line of defense against a number of Gram-negative pathogens. The rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff565377ec3f04a5f5170e6dd7cd1bb
https://europepmc.org/articles/PMC10321319/
https://europepmc.org/articles/PMC10321319/