Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Zongping Xia"'
Autor:
Xin Cui, Xinwei Li, Huimin Zheng, Yun Su, Shuyu Zhang, Mengjie Li, Xiaoyan Hao, Shuo Zhang, Zhengwei Hu, Zongping Xia, Changhe Shi, Yuming Xu, Chengyuan Mao
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Parkinson’s disease (PD) is a neurodegenerative disorder marked by the loss of dopaminergic neurons in the substantia nigra. Despite progress, the pathogenesis remains unclear. Human midbrain organoids (hMLOs) have emerged as a promising m
Externí odkaz:
https://doaj.org/article/ff9ce9ce7d9b44019080af449357aa84
Autor:
Xin Wang, Shen Li, Chen Liu, Jiawei Zhao, Gangfeng Ren, Feng Zhang, Xuyang Liu, Shuang Cao, Yuming Xu, Zongping Xia
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background In mouse models of atherosclerosis, knockout of the PLA2G2A gene has been shown to reduce the volume of atherosclerotic plaques. Clinical trials have demonstrated the potential of using the sPLA2 inhibitor Varespladib in combinati
Externí odkaz:
https://doaj.org/article/39e438bfc66047b1a751b7ca8808a0e4
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Like many other viruses, KSHV has two life cycle modes: the latent phase and the lytic phase. The RTA protein from KSHV is essential for lytic reactivation, but how this protein’s activity is regulated is not fully understood. Here, we rep
Externí odkaz:
https://doaj.org/article/5eb79db6617b44018c16f3d19cefea8c
Autor:
Jiaqi Li, Suying Duan, Jing Yang, Honglin Zheng, Yanpeng Yuan, Mibo Tang, Yanlin Wang, Yutao Liu, Zongping Xia, Haiyang Luo, Yuming Xu
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-10 (2024)
Abstract Background Several studies have indicated that skin holds promise as a potential sample for detecting pathological α-Syn and serving as a diagnostic biomarker for α-synucleinopathies. Despite reports in Chinese PD patients, comprehensive r
Externí odkaz:
https://doaj.org/article/84446f3e54ee4e5e95f736e22d96f921
Autor:
Guangyu Guo, Liyuan Fan, Yingxue Yan, Yunhao Xu, Zhifen Deng, Miaomiao Tian, Yaoqi Geng, Zongping Xia, Yuming Xu
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-12 (2023)
Abstract Since metabolic dysregulation is a hallmark of both stroke and Alzheimer’s disease (AD), mining shared metabolic patterns in these diseases will help to identify their possible pathogenic mechanisms and potential intervention targets. Howe
Externí odkaz:
https://doaj.org/article/8f75c9bf916946aa8c493750b59e7c75
Autor:
Yun Su, Huimin Zheng, Changhe Shi, Xinwei Li, Shuyu Zhang, Guangyu Guo, Wenkai Yu, Shuo Zhang, Zhengwei Hu, Jing Yang, Zongping Xia, Chengyuan Mao, Yuming Xu
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract The meninges, membranes surrounding the central nervous system (CNS) boundary, harbor a diverse array of immunocompetent immune cells, and therefore, serve as an immunologically active site. Meningeal immunity has emerged as a key factor in
Externí odkaz:
https://doaj.org/article/f846b41ddb7541ed998d6f1e7db53529
Autor:
Ruiyao Hu, Jing Liang, Lan Ding, Wan Zhang, Yuying Wang, Yige Zhang, Ding Zhang, Lulu Pei, Xinjing Liu, Zongping Xia, Yuming Xu, Bo Song
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Acute ischemic stroke (AIS) induces high level of neutrophils, which correlates inversely with patient survival. Pyroptosis induced by gasdermin D (GSDMD) has been shown to have an important role in the pathophysiology of several inflammator
Externí odkaz:
https://doaj.org/article/9e1f6efc8c0d43a68760d2f222fbc0c2
Autor:
Shizhe Yu, Haoren Wang, Lingpeng Yang, Yingxue Yan, Qiang Cai, Duo Ma, Long Jiang, Zehai Gao, Zhiyong Yu, Zongping Xia
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-7 (2022)
Measurement(s) mRNA Expression Technology Type(s) spatial transcriptomics Sample Characteristic - Organism Homo sapiens
Externí odkaz:
https://doaj.org/article/4065b352f15b4e74befb30cb584560e3
Autor:
Hongbing Liu, Kai Liu, Ke Zhang, Ce Zong, Hongxun Yang, Yapeng Li, Shen Li, Xin Wang, Jiawei Zhao, Zongping Xia, Bo Song, Xuming Xu, Yuan Gao
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
Background: There is still no precise knowledge of the causes of progression in patients with acute ischemic stroke (AIS), and we are unable to predict patients at risk. Objective: To explore the frequency, predictive factors, and the prognosis of ea
Externí odkaz:
https://doaj.org/article/441e0ac21b40487198a66256539732ba
Autor:
Shizhe Yu, Haoren Wang, Lin Zhang, Qiang Cai, Duo Ma, Jian Zhao, Mengfei Ma, Zhiyong Yu, Zongping Xia
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 7, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/7d17219b864e46379d7a7ed322e8c482