Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Zongjuan Fang"'
Publikováno v:
Wound Repair and Regeneration. 13:A4-A27
Proinflammatory cytokines (such as IL-1 [alpha], IL-1 [beta]) have been shown to play a significant role in early stages of wound healing. Previous studies also indicate that mucosal wounds heal faster in males. The purpose of this study was to asses
Autor:
John P. Lydon, Bilgin Gurates, Franco J. DeMayo, Sijun Yang, Mitsutoshi Tamura, Serdar E. Bulun, Zongjuan Fang
Publikováno v:
Fertility and Sterility. 82:673-678
Objective To determine the role of P and its nuclear receptor PR in the growth of ectopic uterine tissue of mice with or without a disrupted PR gene. Design Animal study. Setting Academic medical center. Animal(s) Female wild-type (WT) and transgenic
Autor:
Sanober Amin, Mitsutoshi Tamura, Gonca Imir, Santanu Deb, Zongjuan Fang, Bertan Yilmaz, Serdar E. Bulun, Bilgin Gurates, David Langoi, Sijun Yang
Publikováno v:
Seminars in Reproductive Medicine. 22:45-50
Aromatase p450 (p450arom) is the key enzyme for biosynthesis of estrogen, which is an essential hormone for the establishment and growth of endometriosis. There is no detectable aromatase enzyme activity in normal endometrium; therefore, estrogen is
WT1 and DAX-1 Inhibit Aromatase P450 Expression in Human Endometrial and Endometriotic Stromal Cells
Autor:
Serdar E. Bulun, Takashi Suzuki, Siby Sebastian, Hironobu Sasano, Bilgin Gurates, Zongjuan Fang, Jianfeng Zhou, Sijun Yang, Mitsutoshi Tamura
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 87:4369-4377
The orphan nuclear receptor steroidogenic factor-1 (SF-1) induces the expression of Müllerian inhibiting substance (MIS) and many steroidogenic genes, including aromatase P450 (P450arom). Dosage-sensitive sex reversal adrenal hypoplasia congenita cr
Autor:
Sijun Yang, Zongjuan Fang, Serdar E. Bulun, Mitsutoshi Tamura, Dean B. Evans, Evan R. Simpson, Bilgin Gurates
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 87:3460-3466
Aromatase P450 (P450arom) is the key enzyme for the biosynthesis of estrogen that is essential for the growth of human endometriosis, a pathology characterized by endometrium-like tissue on the peritoneal surfaces of abdominal organs manifest by pelv
Autor:
Mitsutoshi Tamura, Zongjuan Fang, Karen Ferrer, Serdar E. Bulun, Sijun Yang, Josephine B. Miller, Bilgin Gurates
Publikováno v:
Molecular Endocrinology. 15:2093-2105
Progesterone stimulates the expression of 17β-hydroxysteroid dehydrogenase (HSD) type 2, which catalyzes the conversion of the potent estrogen, E2, to an inactive form, estrone, in epithelial cells of human endometrial tissue. Various effects of pro
Autor:
David Langoi, Gonca Imir, Zongjuan Fang, Sanober Amin, Bilgin Gurates, Santanu Deb, Bertan Yilmaz, Mitsutoshi Tamura, Serdar E. Bulun, Sijun Yang
Publikováno v:
Endometriosis in Clinical Practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d29f6016bb676ee4264f3188b9fb0f0
https://doi.org/10.4324/9780203319390_chapter_9
https://doi.org/10.4324/9780203319390_chapter_9
Autor:
Bilgin Gurates, Zongjuan Fang, Gonca Imir, David Langoi, Sanober Amin, Mitsutoshi Tamura, Serdar E. Bulun, Santanu Deb, Sijun Yang
Publikováno v:
Endometriosis: Advances and Controversies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1117184eb9b60509d51803543c34ab0
https://doi.org/10.1201/b14235-12
https://doi.org/10.1201/b14235-12
Autor:
Bilgin Gurates, Sijun Yang, Mitsutoshi Tamura, Siby Sebastian, Jianfeng Zhou, Sanober Amin, Serdar E. Bulun, Zongjuan Fang, Abraham Amsterdam
Publikováno v:
Molecular and cellular endocrinology. 208(1-2)
Binding activity of steroidogenic factor-1 (SF-1) to promoters of the majority of steroidogenic genes in response to gonadotropins is a critical mechanism that regulates steroidogenesis in gonads. Thus, the modulation of SF-1 action may be essential
Autor:
Kunihiro Okamura, Zongjuan Fang, Serdar E. Bulun, Mitsutoshi Tamura, Sijun Yang, Siby Sebastian, Bilgin Gurates
Publikováno v:
Journal of molecular endocrinology. 31(1)
We previously reported that human malignant endometrial epithelial cell conditioned medium (MECM) up-regulated cyclooxygenase (COX)-2 mRNA and protein levels in human normal endometrial stromal cells (ESC). Here we showed that pretreatment with a sel