Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zonggen Peng"'
Autor:
Hongying Li, Jianrui Li, Jiayu Li, Hu Li, Xuekai Wang, Jing Jiang, Lei Lei, Han Sun, Mei Tang, Biao Dong, Weiqing He, Shuyi Si, Bin Hong, Yinghong Li, Danqing Song, Zonggen Peng, Yongsheng Che, Jian-Dong Jiang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 6, Pp 2567-2580 (2024)
The pandemic of SARS-CoV-2 worldwide with successive emerging variants urgently calls for small-molecule oral drugs with broad-spectrum antiviral activity. Here, we show that carrimycin, a new macrolide antibiotic in the clinic and an antiviral candi
Externí odkaz:
https://doaj.org/article/0c69026a221e410791cdc5a1b0b2f32b
Autor:
Meng-Hao Huang, Hu Li, Rong Xue, Jianrui Li, Lihua Wang, Junjun Cheng, Zhouyi Wu, Wenjing Li, Jinhua Chen, Xiaoqin Lv, Qiang Li, Pei Lan, Limin Zhao, Yongfeng Yang, Zonggen Peng, Jiandong Jiang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 9, Iss 4, Pp 769-781 (2019)
Bicyclol is a synthetic drug for hepatoprotection in clinic since 2004. Preliminary clinical observations suggest that bicyclol might be active against hepatitis C virus (HCV) with unknown mechanism. Here, we showed that bicyclol significantly inhibi
Externí odkaz:
https://doaj.org/article/34065049ee2046da9a9bb266e5e46b43
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 5, Iss 3, Pp 201-209 (2015)
A series of novel N-phenylbenzamide and N-phenylacetophenone compounds were synthesized and evaluated for their antiviral activity against HCV and EV71 (strain SZ-98). The biological results showed that three compounds (23, 25 and 41) exhibited consi
Externí odkaz:
https://doaj.org/article/fb01be7dbaed414cb38f6f5bea6c99d1
Autor:
Zhen Yang, Yongxin Yu, Hongzhong Zhang, Guifang Shang, Jialiang Gao, Jian-Dong Jiang, Zonggen Peng
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 4, Iss 4, Pp 266-269 (2014)
HCV genotypes have been documented in clinical practice. The aim of this study was to determine the replication priority of different HCV genotypes in a Chinese HCV positive cohort. Serum samples from 491 apparently healthy Chinese blood donors testi
Externí odkaz:
https://doaj.org/article/e9a0d9c6a03a45a5b13a439391eecded
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 4, Iss 4, Pp 241-247 (2014)
Interferon (IFN) in combination with ribavirin has been the standard of care (SOC) for chronic hepatitis C for the past few decades. Although the current SOC lacks the desired efficacy, and 4 new direct-acting antiviral agents have been recently appr
Externí odkaz:
https://doaj.org/article/4c043ac914a94e44ad84130a30db2767
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 4, Iss 4, Pp 307-312 (2014)
Chronic hepatitis C virus (HCV) infection has become a major public health burden worldwide. Twenty-two sophocarpinic acid or matrine derivatives were synthesized and their anti-HCV activities were evaluated in vitro. The structure-activity analysis
Externí odkaz:
https://doaj.org/article/58ee6e711779431a862d1796f01f06aa
Autor:
Jiao Li, Yujia Wang, Xiaomeng Hao, Shasha Li, Jia Jia, Yan Guan, Zonggen Peng, Hongkai Bi, Chunling Xiao, Shan Cen, Maoluo Gan
Publikováno v:
Molecules, Vol 24, Iss 15, p 2821 (2019)
A new pyrazine derivative, trypilepyrazinol (1), a new α-pyrone polyketide, (+)-neocitreoviridin (2), and a new ergostane analogue, 3β-hydroxyergosta-8,14,24(28)-trien-7-one (3), were isolated and characterized along with five known compounds from
Externí odkaz:
https://doaj.org/article/957eb5becd9a4efeac56ed97ea1679a2
Autor:
Yanping Li, Zonggen Peng, Lanhu Hao, Zhouyi Wu, Yanping Zhu, Laixing Hu, Jiandong Jiang, Zhuorong Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 3, Iss 5, Pp 312-321 (2013)
A series of novel amino-substituted N-aryl benzamide analogs were synthesized and evaluated for their ability to inhibit hepatitis C virus (HCV) replication in acutely infected Huh7.5 cells. Most of the substituted N-aryl benzamide compounds showed c
Externí odkaz:
https://doaj.org/article/0e490ff6b8064353a9c487b7ea756c56
Autor:
Xiaomeng, Hao, Shasha, Li, Guiyang, Wang, Jianrui, Li, Zonggen, Peng, Yuqin, Zhang, Liyan, Yu, Maoluo, Gan
Publikováno v:
Journal of natural products. 85(7)
Zelkovamycins F and G (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5705d0156a58700b440a7e31b08ac021
https://pubmed.ncbi.nlm.nih.gov/35715218
https://pubmed.ncbi.nlm.nih.gov/35715218
Autor:
Meixi Wang, Jianrui Li, Hu Li, Biao Dong, Jing Jiang, Nannan Liu, Jiali Tan, Xuekai Wang, Lei Lei, Hongying Li, Han Sun, Mei Tang, Huiqiang Wang, Haiyan Yan, Yuhuan Li, Jiandong Jiang, Zonggen Peng
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5544
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, and there is no specific drug to treat it. Recent results showed that 17-beta-hydroxysteroid dehydrogenase type 13 (HSD17B13) is associated with liver disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546910dc4e1dfa3064e1a15a7b64d7c2