Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Zongfang Yang"'
Autor:
Stefano Nardone, Roberto De Luca, Antonino Zito, Nataliya Klymko, Dimitris Nicoloutsopoulos, Oren Amsalem, Cory Brannigan, Jon M. Resch, Christopher L. Jacobs, Deepti Pant, Molly Veregge, Harini Srinivasan, Ryan M. Grippo, Zongfang Yang, Mark L. Zeidel, Mark L. Andermann, Kenneth D. Harris, Linus T. Tsai, Elda Arrigoni, Anne M. J. Verstegen, Clifford B. Saper, Bradford B. Lowell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The “dorsal pons”, or “dorsal pontine tegmentum” (dPnTg), is part of the brainstem. It is a complex, densely packed region whose nuclei are involved in regulating many vital functions. Notable among them are the parabrachial nucleus,
Externí odkaz:
https://doaj.org/article/f281b415638047cf935491423b9003e6
Publikováno v:
Brain and Behavior, Vol 11, Iss 8, Pp n/a-n/a (2021)
Abstract Background There is no clear time point for the onset of depression and anxiety in Parkinson's disease (PD), and their atypical physical symptoms often overlap with other nonmotor symptoms. Autonomic dysfunction usually appears earlier than
Externí odkaz:
https://doaj.org/article/399919a32aad4f8cbe70d97c97f2229d
Autor:
Yael Mandelblat-Cerf, Rohan N Ramesh, Christian R Burgess, Paola Patella, Zongfang Yang, Bradford B Lowell, Mark L Andermann
Publikováno v:
eLife, Vol 4 (2015)
Agouti-related-peptide (AgRP) neurons—interoceptive neurons in the arcuate nucleus of the hypothalamus (ARC)—are both necessary and sufficient for driving feeding behavior. To better understand the functional roles of AgRP neurons, we performed o
Externí odkaz:
https://doaj.org/article/c7b4a3efe6094c6a915bb647a01edd76
Autor:
Jon Resch, Amelia Douglass, Joseph Madara, Hakan Kucukdereli, Ofer Yizhar, Abhinav Grama, Masahito Yamagata, Zongfang Yang, Bradford Lowell
Publikováno v:
Physiology. 38
Fasting initiates a multitude of adaptations to allow survival. Activation of the hypothalamic-pituitary-adrenal (HPA) axis and subsequent release of glucocorticoid hormones is a key response that mobilizes fuel stores to meet energy demands. Despite
Autor:
Bhavna N. Desai, Bradford B. Lowell, Chengcheng Jin, Mark P. Jedrychowski, Bo Hu, Zongfang Yang, Xing Zeng, Alexander S. Banks, Jon M. Resch, Diane Mathis, Bruce M. Spiegelman
Publikováno v:
Nature
The sympathetic nervous system innervates peripheral organs to regulate their function and maintain homeostasis, whereas target cells also produce neurotrophic factors to promote sympathetic innervation1,2. The molecular basis of this bi-directional
Publikováno v:
Brain and Behavior, Vol 11, Iss 8, Pp n/a-n/a (2021)
Brain and Behavior
Brain and Behavior
Background There is no clear time point for the onset of depression and anxiety in Parkinson's disease (PD), and their atypical physical symptoms often overlap with other nonmotor symptoms. Autonomic dysfunction usually appears earlier than motor sym
Autor:
Anne M.J. Verstegen, Bhavik P. Shah, Zongfang Yang, Henning Fenselau, Jon M. Resch, Jie Xu, John N. Campbell, Joseph C. Madara, Bradford B. Lowell, Yoav Livneh, Yael Mandelblat-Cerf
Publikováno v:
Nature Neuroscience. 20:42-51
Arcuate nucleus (ARC) neurons sense the fed or fasted state and regulate hunger. Agouti-related protein (AgRP) neurons in the ARC (ARCAgRP neurons) are stimulated by fasting and, once activated, they rapidly (within minutes) drive hunger. Pro-opiomel
Publikováno v:
Journal of affective disorders. 256
Background Most studies in Parkinson's disease (PD) have focused on the direct effects of social support and self-efficacy on caregiver burden. This study aimed to test our prediction that caregiver self-efficacy and social support were two chaining
Autor:
Zongfang Yang, Pratik Aryal, Bradford B. Lowell, Kerry Wellenstein, Dong Kong, John N. Campbell, Yossi Dagon, Barbara B. Kahn, Xinchi Yi, Yikun Guo, Bernardo L. Sabatini
Publikováno v:
Neuron. 91:25-33
AMP-activated protein kinase (AMPK) plays an important role in regulating food intake. The downstream AMPK substrates and neurobiological mechanisms responsible for this, however, are ill-defined. Agouti-related peptide (AgRP)-expressing neurons in t
Autor:
David P. Olson, Bhavik P. Shah, Chianping Ye, Joel K. Elmquist, Zongfang Yang, Michael J. Krashes, Patrick M. Fuller, Shuichi Koda, Linh Vong, Bradford B. Lowell
Publikováno v:
Proceedings of the National Academy of Sciences. 111:13193-13198
Activation of melanocortin-4 receptors (MC4Rs) restrains feeding and prevents obesity; however, the identity, location, and axonal projections of the neurons bearing MC4Rs that control feeding remain unknown. Reexpression of MC4Rs on single-minded 1