Zobrazeno 1 - 10
of 347
pro vyhledávání: '"Zong-Wan Mao"'
Autor:
Qixin Chen, Liu-Yi Liu, Zhiqi Tian, Zhou Fang, Kang-Nan Wang, Xintian Shao, Chengying Zhang, Weiwei Zou, Fiona Rowan, Kangqiang Qiu, Baohua Ji, Jun-Lin Guan, Dechang Li, Zong-Wan Mao, Jiajie Diao
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113472- (2023)
Summary: Mitochondria are dynamic organelles that undergo fusion and fission events, in which the mitochondrial membrane and DNA (mtDNA) play critical roles. The spatiotemporal organization of mtDNA reflects and impacts mitochondrial dynamics. Herein
Externí odkaz:
https://doaj.org/article/79c5133bf3d24540ab4709e1f0e94e52
Autor:
Jinhui Wang, Xiaoshuai Sun, Yanxuan Xie, Yan Long, Huowen Chen, Xiaojun He, Taotao Zou, Zong-Wan Mao, Wei Xia
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
The opportunistic pathogen Pseudomonas aeruginosa (P. aeruginosa) causes infections that are difficult to treat, which is due to the bacterial resistance to antibiotics. We herein identify a gold(I) N-heterocyclic carbene compound as a highly potent
Externí odkaz:
https://doaj.org/article/a89efcf20d59477083b40b67d4b12abc
Autor:
Liping Huang, Hang Zhang, Shanshan Wu, Xin Xu, Lingling Zhang, Hongbing Ji, Liang He, Yuna Qian, Zhiyong Wang, Yongming Chen, Jianliang Shen, Zong-Wan Mao, Zhegang Huang
Publikováno v:
iScience, Vol 19, Iss , Pp 224-231 (2019)
Summary: Despite the success for targeted delivery in the body, the efficient release without side effects caused by residual drug remains a challenge. For reducing residual drug, the pH-responsive carriers were prepared by self-assembly from aromati
Externí odkaz:
https://doaj.org/article/7df712be4ce54452ab0ef80229847d9a
Autor:
Kang‐Nan Wang, Xintian Shao, Zhiqi Tian, Liu‐Yi Liu, Chengying Zhang, Cai‐Ping Tan, Jie Zhang, Peixue Ling, Fei Liu, Qixin Chen, Jiajie Diao, Zong‐Wan Mao
Publikováno v:
Advanced Science, Vol 8, Iss 17, Pp n/a-n/a (2021)
Abstract Oncosis, depending on DNA damage and mitochondrial swelling, is an important approach for treating cancer and other diseases. However, little is known about the behavior of mitochondria during oncosis, due to the lack of probes for in situ v
Externí odkaz:
https://doaj.org/article/d74ffc20f95f4b6e99232e392399cbb8
Autor:
Kang‐Nan Wang, Liu‐Yi Liu, Guobin Qi, Xi‐Juan Chao, Wen Ma, Zhiqiang Yu, Qiling Pan, Zong‐Wan Mao, Bin Liu
Publikováno v:
Advanced Science, Vol 8, Iss 8, Pp n/a-n/a (2021)
Abstract Nuclei and mitochondria are the only cellular organelles containing genes, which are specific targets for efficient cancer therapy. So far, several photosensitizers have been reported for mitochondria targeting, and another few have been rep
Externí odkaz:
https://doaj.org/article/c5222e35d99d466f90b7190bea79d3a9
Publikováno v:
Molecules, Vol 27, Iss 8, p 2439 (2022)
Quorum sensing (QS) is a cell-to-cell communication process that controls bacterial collective behaviors. The QS network regulates and coordinates bacterial virulence factor expression, antibiotic resistance and biofilm formation. Therefore, inhibiti
Externí odkaz:
https://doaj.org/article/ff563e2d0a404efea68f345e8ea3be3c
Publikováno v:
Molecules, Vol 27, Iss 9, p 2629 (2022)
As hypoxia is closely associated with tumor progression, proliferation, invasion, metastasis, and strong resistance to therapy, regulating and overcoming the hypoxia tumor microenvironment are two increasingly important aspects of tumor treatment. He
Externí odkaz:
https://doaj.org/article/5126861d5b154ed0a0ab4a246340a3ef
Autor:
Wenting Liu, Yi-Fang Zhong, Liu-Yi Liu, Chu-Tong Shen, Wenjuan Zeng, Fuyi Wang, Danzhou Yang, Zong-Wan Mao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
DNA G-quadruplexes occur in oncologically relevant regions, thus are interesting targets for cancer research and treatment. Here, the authors solved the 1:1 and 4:2 (ligand/DNA) NMR structures of human telomeric DNA in complex with platinum(II)-tripo
Externí odkaz:
https://doaj.org/article/b86abdb8dcab48ffa099caa1ceb4eeee
Publikováno v:
Advanced Science, Vol 7, Iss 1, Pp n/a-n/a (2020)
Abstract Ruthenium complexes are promising photosensitizers (PSs), but their clinical applications have many limitations. Here, a multifunctional nano‐platform PDA‐Pt‐CD@RuFc formed by platinum‐decorated and cyclodextrin (CD)‐modified polyd
Externí odkaz:
https://doaj.org/article/9e927679e7f44fb3919c9f4e0f5ec4e9
Publikováno v:
Chemical Society Reviews. 52:2790-2832
Organometallics act through specific biomolecular targets or tumor homeostasis perturbation to induce various cell death pathways.