Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Zong-Hong Zhang"'
Autor:
Jacob Gratten, Qiongyi Zhao, Beben Benyamin, Fleur Garton, Ji He, Paul J. Leo, Marie Mangelsdorf, Lisa Anderson, Zong-Hong Zhang, Lu Chen, Xiang-Ding Chen, Katie Cremin, Hong-Weng Deng, Janette Edson, Ying-Ying Han, Jessica Harris, Anjali K. Henders, Zi-Bing Jin, Zhongshan Li, Yong Lin, Xiaolu Liu, Mhairi Marshall, Bryan J. Mowry, Shu Ran, David C. Reutens, Sharon Song, Li-Jun Tan, Lu Tang, Robyn H. Wallace, Lawrie Wheeler, Jinyu Wu, Jian Yang, Huji Xu, Peter M. Visscher, Perry F. Bartlett, Matthew A. Brown, Naomi R. Wray, Dongsheng Fan
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-9 (2017)
Abstract Background Amyotrophic lateral sclerosis (ALS) is a progressive neurological disease characterised by the degeneration of motor neurons, which are responsible for voluntary movement. There remains limited understanding of disease aetiology,
Externí odkaz:
https://doaj.org/article/98e8341b26c046c8b5ac3b8ba4dc00bc
Autor:
Beben Benyamin, Ji He, Qiongyi Zhao, Jacob Gratten, Fleur Garton, Paul J. Leo, Zhijun Liu, Marie Mangelsdorf, Ammar Al-Chalabi, Lisa Anderson, Timothy J. Butler, Lu Chen, Xiang-Ding Chen, Katie Cremin, Hong-Weng Deng, Matthew Devine, Janette Edson, Jennifer A. Fifita, Sarah Furlong, Ying-Ying Han, Jessica Harris, Anjali K. Henders, Rosalind L. Jeffree, Zi-Bing Jin, Zhongshan Li, Ting Li, Mengmeng Li, Yong Lin, Xiaolu Liu, Mhairi Marshall, Emily P. McCann, Bryan J. Mowry, Shyuan T. Ngo, Roger Pamphlett, Shu Ran, David C. Reutens, Dominic B. Rowe, Perminder Sachdev, Sonia Shah, Sharon Song, Li-Jun Tan, Lu Tang, Leonard H. van den Berg, Wouter van Rheenen, Jan H. Veldink, Robyn H. Wallace, Lawrie Wheeler, Kelly L. Williams, Jinyu Wu, Xin Wu, Jian Yang, Weihua Yue, Zong-Hong Zhang, Dai Zhang, Peter G. Noakes, Ian P. Blair, Robert D. Henderson, Pamela A. McCombe, Peter M. Visscher, Huji Xu, Perry F. Bartlett, Matthew A. Brown, Naomi R. Wray, Dongsheng Fan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease. Here, Wray and colleagues identify association of the GPX3-TNIP1 locus with ALS using cross-ethnic meta-analyses.
Externí odkaz:
https://doaj.org/article/522153208176401ebf7630ef7ecef4a7
Autor:
Ram Maharjan, Lyndal Henden, Kelly L. Williams, Alison L. Hogan, Benjamin Heng, Ian P. Blair, Sandrine Chan Moi Fat, Ingrid S. Tarr, Natalie Grima, Shu Yang, Katharine Y. Zhang, Amy K. Cain, Qiongyi Zhao, Sharlynn Wu, Marco Morsch, Amanda L. Wright, Jennifer A. Fifita, Albert Lee, Stephanie L. Rayner, Zong-Hong Zhang, Emily P. McCann
Publikováno v:
Neuropathology and applied neurobiologyREFERENCES. 47(7)
Aim Splicing factor proline and glutamine rich (SFPQ) is an RNA-DNA binding protein that is dysregulated in Alzheimer's disease and frontotemporal dementia. Dysregulation of SFPQ, specifically increased intron retention and nuclear depletion, has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d9536a5750fda5f41871d0d32f7ead
https://pubmed.ncbi.nlm.nih.gov/34288034
https://pubmed.ncbi.nlm.nih.gov/34288034
Autor:
Lyndal Henden, Qiongyi Zhao, Benjamin Heng, Ram Maharjan, Shu Yang, Sharlynn Wu, Ian P. Blair, Amy K. Cain, Ingrid S. Tarr, Zong-Hong Zhang, Natalie Grima, Katharine Y. Zang, Emily P. McCann, Kelly L. Williams, Sandrine Chan Moi Fat, Alison L. Hogan, Jennifer A. Fifita, Marco Morsch, Amanda L. Wright
BackgroundSplicing factor proline and glutamine rich (SFPQ, also known as polypyrimidine tract-binding protein-associated-splicing factor, PSF) is a RNA-DNA binding protein with roles in key cellular pathways such as DNA transcription and repair, RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aef207e003688cad0957ec184671e642
https://doi.org/10.1101/2020.09.22.309062
https://doi.org/10.1101/2020.09.22.309062
Autor:
Ingrid S. Tarr, Beben Benyamin, Natalie A. Twine, Denis C. Bauer, Emily P. McCann, Garth A. Nicholson, Qiongyi Zhao, Dominic B. Rowe, Tim J Peters, Ian P. Blair, Susan J. Clark, Kelly L. Williams, Katharine Y. Zhang, Zong Hong Zhang
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterised by the loss of upper and lower motor neurons. ALS exhibits high phenotypic variability including age and site of onset, and disease duration. To uncover epigenetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6107b8d49a98eab6aca8fb86ca28622
https://hdl.handle.net/11541.2/138138
https://hdl.handle.net/11541.2/138138
Autor:
Wei Wei, Timothy W. Bredy, Janette Edson, Xiang Li, David C. Reutens, Zong Hong Zhang, Qiongyi Zhao, Min Chen
Publikováno v:
Epilepsy Research. 166:106400
Objectives This study profiled circulating and hippocampal microRNAs (miRNAs) to identify alterations associated with the risk of epileptogenesis in a mouse temporal lobe epilepsy model. Methods Next-generation sequencing was performed to examine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f0c669958b14a7642f8cba8acafbe7
https://doi.org/10.1016/j.eplepsyres.2020.106400
https://doi.org/10.1016/j.eplepsyres.2020.106400
Autor:
Qiongyi Zhao, Chao Feng, Xiang Li, Timothy W. Bredy, Esmi L. Zajaczkowski, Wei Wei, Paul R. Marshall, Laura J. Leighton, Robert C. Spitale, Zong Hong Zhang, Sarah Nainar
Publikováno v:
ACS chemical neuroscience, vol 9, iss 7
Transcriptome-wide expression profiling of neurons has provided important insights into the underlying molecular mechanisms and gene expression patterns that transpire during learning and memory formation. However, there is a paucity of tools for pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6680c9481621b1588c53bba99ab9966
https://escholarship.org/uc/item/4kz9p4pj
https://escholarship.org/uc/item/4kz9p4pj
Autor:
Zhongshan Li, Xiang-Ding Chen, Xiaolu Liu, Yingying Han, Robyn H. Wallace, Paul Leo, Zong Hong Zhang, Dongsheng Fan, Qiongyi Zhao, Li-Jun Tan, Matthew A. Brown, Ji He, Naomi R. Wray, Janette Edson, Zi-Bing Jin, Perry F. Bartlett, Sharon Song, Jian Yang, Lawrie Wheeler, Bryan J. Mowry, Jacob Gratten, Fleur C. Garton, Lu Chen, Mhairi Marshall, Huji Xu, Shu Ran, Yong Lin, Lu Tang, Peter M. Visscher, Hong-Weng Deng, Jessica Harris, Lisa Anderson, Anjali K. Henders, David C. Reutens, Jinyu Wu, Marie Mangelsdorf, Katie Cremin, Beben Benyamin
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-9 (2017)
Genome Medicine
Genome Medicine
Background Amyotrophic lateral sclerosis (ALS) is a progressive neurological disease characterised by the degeneration of motor neurons, which are responsible for voluntary movement. There remains limited understanding of disease aetiology, with medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5803829f1d8889e69196493e7fd7559
https://doi.org/10.1186/s13073-017-0487-0
https://doi.org/10.1186/s13073-017-0487-0
Autor:
Qiongyi Zhao, Sarah Furlong, Robert D. Henderson, Zong Hong Zhang, Sonia Shah, Pamela A. McCombe, Anjali K. Henders, Perminder S. Sachdev, Zhijun Liu, Kathryn A Thorpe, Beben Benyamin, Fleur C. Garton, Jacob Gratten, Sarah Morgan, Susan Heggie, Matthew R. Robinson, Casey M. M. Pfluger, Janette Edson, Peter M. Visscher, Naomi R. Wray, Allan F. McRae, Karen A. Mather, Marie Mangelsdorf
Publikováno v:
Molecular Genetics & Genomic Medicine
Background: Gene discovery has provided remarkable biological insights into amyotrophic lateral sclerosis (ALS). One challenge for clinical application of genetic testing is critical evaluation of the significance of reported variants. Methods: We us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5563a90348b9082a85e1a8c319b218d7
https://pubmed.ncbi.nlm.nih.gov/28717666
https://pubmed.ncbi.nlm.nih.gov/28717666
Autor:
Gratten, Jacob, Qiongyi Zhao, Beben Benyamin, Garton, Fleur, He, Ji, Leo, Paul, Mangelsdorf, Marie, Anderson, Lisa, Zong-Hong Zhang, Chen, Lu, Xiang-Ding Chen, Cremin, Katie, Hong-Weng Deng, Edson, Janette, Han, Ying-Ying, Harris, Jessica, Henders, Anjali, Zi-Bing Jin, Zhongshan Li, Lin, Yong, Xiaolu Liu, Marshall, Mhairi, Mowry, Bryan, Ran, Shu, Reutens, David, Song, Sharon, Tan, Li-Jun, Tang, Lu, Wallace, Robyn, Wheeler, Lawrie, Wu, Jinyu, Yang, Jian, Huji Xu, Visscher, Peter, Bartlett, Perry, Brown, Matthew, Wray, Naomi, Dongsheng Fan
Quantileâ quantile plots for exome-wide gene-based testing of rare coding variants in the primary analysis of 610 cases and 460 controls. (DOCX 235 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef37f5f42f9719940d54f37c97d7e0df