Augmented ERO1α upon mTORC1 activation induces ferroptosis resistance and tumor progression via upregulation of SLC7A11.

Autor: Wang, Zixi^1,2 (AUTHOR), Zong, Huaiyuan¹ (AUTHOR), Liu, Weiwei³ (AUTHOR), Lin, Wei⁴ (AUTHOR), Sun, Anjiang¹ (AUTHOR), Ding, Zhao³ (AUTHOR), Chen, Xu¹ (AUTHOR), Wan, Xiaofeng⁵ (AUTHOR), Liu, Yanyan⁶ (AUTHOR), Hu, Zhongdong⁷ (AUTHOR), Zhang, Hongbing⁸ (AUTHOR), Li, Hongwu^3,9 (AUTHOR), Liu, Yehai³ (AUTHOR), Li, Dapeng¹⁰ (AUTHOR) ldpeagle1@163.com, Zhang, Sumei¹ (AUTHOR) zhangsumei@ahmu.edu.cn, Zha, Xiaojun^1,10 (AUTHOR) zhaxiaojunpumc@gmail.com

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 4/13/2024, Vol. 43, p1-22. 22p.

Characterization of dipyridamole as a novel ferroptosis inhibitor and its therapeutic potential in acute respiratory distress syndrome management.

Autor: Chen X; Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; Department of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China.; Anhui Geriatric Institute, Hefei, Anhui, China., Shen J; Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; Department of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China.; Anhui Geriatric Institute, Hefei, Anhui, China., Jiang X; Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; Anhui Geriatric Institute, Hefei, Anhui, China.; Key Laboratory of Respiratory Diseases Research and Medical Transformation of Anhui Province, Hefei, Anhui, China., Pan M; Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; Department of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China.; Anhui Geriatric Institute, Hefei, Anhui, China., Chang S; Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; Department of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China.; Anhui Geriatric Institute, Hefei, Anhui, China., Li J; Department of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China., Wang L; Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; Anhui Geriatric Institute, Hefei, Anhui, China., Miao M; Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; Department of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China.; Anhui Geriatric Institute, Hefei, Anhui, China., Feng X; Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; Anhui Geriatric Institute, Hefei, Anhui, China., Zhang L; Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; Department of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China.; Anhui Geriatric Institute, Hefei, Anhui, China., Shu G; Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; Anhui Geriatric Institute, Hefei, Anhui, China., Liu W; Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; Department of Thoracic Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Xu F; Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; Anhui Geriatric Institute, Hefei, Anhui, China., Zhang W; Department of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China., Ding Z; Department of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China., Zong H; Department of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China., Liu W; Department of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China., Li D; Department of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China., Chen B; Information Materials and Intelligent Sensing Laboratory of Anhui Province, Institutes of Physical Science and Information Technology, Anhui University, Hefei, Anhui, China., Shao M; Department of Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Fei G; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; Key Laboratory of Respiratory Diseases Research and Medical Transformation of Anhui Province, Hefei, Anhui, China., Zha X; Department of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China., Fan X; Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; Anhui Geriatric Institute, Hefei, Anhui, China.; Key Laboratory of Respiratory Diseases Research and Medical Transformation of Anhui Province, Hefei, Anhui, China.

Publikováno v: Theranostics [Theranostics] 2024 Oct 21; Vol. 14 (18), pp. 6947-6968. Date of Electronic Publication: 2024 Oct 21 (Print Publication: 2024).