Novel Bacteroides Vulgatus strain protects against gluten-induced break of human celiac gut epithelial homeostasis: a pre-clinical proof-of-concept study.

Autor: Tran T; Mucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Senger S; Center for Scientific Review, National Institutes of Health, Bethesda, MD, USA., Baldassarre M; NICU, University of Bari, Bari, Italy., Brosnan RA; Mucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Cristofori F; Pediatric Unit 'Bruno Trambusti', Osp Pediatrico Giovanni XXIII, University of Bari, Bari, Italy., Crocco M; Department of Pediatrics, IRCCS Ospedale Giannina Gaslini, Genova, Italy., De Santis S; Digestive Health Research Institute, Case Western Reserve University School of Medicine, Cleveland, OH, USA.; Department of Pathology, Case Western University School of Medicine, Cleveland, OH, USA., Elli L; Celiac Disease Referral Center, Ospedale Maggiore Policlinico, Milan, Italy., Faherty CS; Mucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Francavilla R; Pediatric Unit 'Bruno Trambusti', Osp Pediatrico Giovanni XXIII, University of Bari, Bari, Italy., Goodchild-Michelman I; Mucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Kenyon VA; Mucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Leonard MM; Mucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Division of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, Mass General for Children, Boston, MA, USA., Lima RS; Mucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Malerba F; Department of Pediatrics, IRCCS Ospedale Giannina Gaslini, Genova, Italy., Montuori M; Pediatric Gastroenterology Unit, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy., Morelli A; Pediatric Training Program, University of Salerno School of Medicine, Salerno, Italy., Norsa L; Pediatric Hepatology Gastroenterology and Transplant Unit, Ospedale Papa Giovanni XXIII Bergamo, Bergamo, Italy., Passaro T; Celiac Disease Referral Center, 'San Giovanni di Dio e Ruggi d'Aragona' University Hospital, Pole of Cava de' Tirreni, Salerno, Italy., Piemontese P; NICU, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy., Reed JC; Mucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Division of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, Mass General for Children, Boston, MA, USA., Sansotta N; Pediatric Hepatology Gastroenterology and Transplant Unit, Ospedale Papa Giovanni XXIII Bergamo, Bergamo, Italy., Valitutti F; Pediatric Gastroenterology and Liver Unit, Santobono-Pausilipon Children's Hospital, Naples, Italy.; European Biomedical Research Institute of Salerno, Salerno, Italy., Zomorrodi AR; Mucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Fasano A; Mucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital; Department of Pediatrics, Harvard Medical School, Boston, MA, USA. afasano@mgh.harvard.edu.; Division of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, Mass General for Children, Boston, MA, USA. afasano@mgh.harvard.edu.; European Biomedical Research Institute of Salerno, Salerno, Italy. afasano@mgh.harvard.edu.

Publikováno v: Pediatric research [Pediatr Res] 2024 Apr; Vol. 95 (5), pp. 1254-1264. Date of Electronic Publication: 2024 Jan 04.

Characterization of the blood microbiota in children with Celiac disease.

Autor: Mehrotra I; Center for Celiac Research and Treatment, MassGeneral Hospital for Children, Yawkey Center for Outpatient Care, Suite 6B, 32 Fruit Street, Boston, MA 02114, USA., Serena G; Center for Celiac Research and Treatment, MassGeneral Hospital for Children, Yawkey Center for Outpatient Care, Suite 6B, 32 Fruit Street, Boston, MA 02114, USA.; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Jackson, 55 Fruit Street, Boston, MA 02114, USA.; Celiac Research Program, Harvard Medical School, Boston, MA, USA., Cetinbas M; Harvard Medical School, 25 Shattuck St, Boston, MA 02115, USA.; Department of Molecular Biology, Massachusetts General Hospital, Simches Research Center, 185 Cambridge Street, CPZN7250 Boston, MA 02114, USA., Kenyon V; Center for Celiac Research and Treatment, MassGeneral Hospital for Children, Yawkey Center for Outpatient Care, Suite 6B, 32 Fruit Street, Boston, MA 02114, USA.; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Jackson, 55 Fruit Street, Boston, MA 02114, USA.; Celiac Research Program, Harvard Medical School, Boston, MA, USA., Martin VM; Harvard Medical School, 25 Shattuck St, Boston, MA 02115, USA.; Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Yawkey Center for Outpatient Care, Yawkey 6B-6800 Suite, 55 Fruit Street Boston, MA 02114, USA.; Food Allergy Center, Massachusetts General Hospital, MGH Professional Office Building, Suite 530, 275 Cambridge Street Boston, MA 02114, USA., Harshman SG; Harvard Medical School, 25 Shattuck St, Boston, MA 02115, USA.; Eating Disorders Clinical and Research Program, Massachusetts General Hospital: West End Apartments 2 Longfellow Place, Suite 200 Boston, MA 02114, USA.; Neuroendocrine Unit, Massachusetts General Hospital, 100 Blossom St, Boston, MA 02114, USA., Zomorrodi AR; Center for Celiac Research and Treatment, MassGeneral Hospital for Children, Yawkey Center for Outpatient Care, Suite 6B, 32 Fruit Street, Boston, MA 02114, USA.; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Jackson, 55 Fruit Street, Boston, MA 02114, USA.; Celiac Research Program, Harvard Medical School, Boston, MA, USA.; Harvard Medical School, 25 Shattuck St, Boston, MA 02115, USA., Sadreyev RI; Harvard Medical School, 25 Shattuck St, Boston, MA 02115, USA.; Department of Molecular Biology, Massachusetts General Hospital, Simches Research Center, 185 Cambridge Street, CPZN7250 Boston, MA 02114, USA., Fasano A; Center for Celiac Research and Treatment, MassGeneral Hospital for Children, Yawkey Center for Outpatient Care, Suite 6B, 32 Fruit Street, Boston, MA 02114, USA.; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Jackson, 55 Fruit Street, Boston, MA 02114, USA.; Celiac Research Program, Harvard Medical School, Boston, MA, USA.; Harvard Medical School, 25 Shattuck St, Boston, MA 02115, USA.; Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Yawkey Center for Outpatient Care, Yawkey 6B-6800 Suite, 55 Fruit Street Boston, MA 02114, USA., Leonard MM; Center for Celiac Research and Treatment, MassGeneral Hospital for Children, Yawkey Center for Outpatient Care, Suite 6B, 32 Fruit Street, Boston, MA 02114, USA.; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Jackson, 55 Fruit Street, Boston, MA 02114, USA.; Celiac Research Program, Harvard Medical School, Boston, MA, USA.; Harvard Medical School, 25 Shattuck St, Boston, MA 02115, USA.; Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Yawkey Center for Outpatient Care, Yawkey 6B-6800 Suite, 55 Fruit Street Boston, MA 02114, USA.

Publikováno v: Current research in microbial sciences [Curr Res Microb Sci] 2021 Aug 30; Vol. 2, pp. 100069. Date of Electronic Publication: 2021 Aug 30 (Print Publication: 2021).

Microbiota and Metabolomic Patterns in the Breast Milk of Subjects with Celiac Disease on a Gluten-Free Diet.

Autor: Olshan KL; Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Harvard Medical School, Boston, MA 02114, USA.; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Boston, MA 02129, USA.; Department of Pediatrics, Harvard Medical School, Harvard University, Boston, MA 02115, USA.; Celiac Research Program, Harvard Medical School, Boston, MA 02115, USA., Zomorrodi AR; Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Harvard Medical School, Boston, MA 02114, USA.; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Boston, MA 02129, USA.; Department of Pediatrics, Harvard Medical School, Harvard University, Boston, MA 02115, USA.; Celiac Research Program, Harvard Medical School, Boston, MA 02115, USA., Pujolassos M; Theoreo srl, University of Salerno, 84084 Salerno, Italy., Troisi J; Theoreo srl, University of Salerno, 84084 Salerno, Italy.; Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, 84084 Salerno, Italy.; European Biomedical Research Institute of Salerno (EBRIS), Via S. De Renzi, 50, 84125 Salerno, Italy., Khan N; CosmosID Inc., Rockville, MD 20850, USA., Fanelli B; CosmosID Inc., Rockville, MD 20850, USA., Kenyon V; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Boston, MA 02129, USA.; Celiac Research Program, Harvard Medical School, Boston, MA 02115, USA., Fasano A; Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Harvard Medical School, Boston, MA 02114, USA.; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Boston, MA 02129, USA.; Department of Pediatrics, Harvard Medical School, Harvard University, Boston, MA 02115, USA.; Celiac Research Program, Harvard Medical School, Boston, MA 02115, USA.; Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, 84084 Salerno, Italy., Leonard MM; Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Harvard Medical School, Boston, MA 02114, USA.; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Boston, MA 02129, USA.; Department of Pediatrics, Harvard Medical School, Harvard University, Boston, MA 02115, USA.; Celiac Research Program, Harvard Medical School, Boston, MA 02115, USA.

Publikováno v: Nutrients [Nutrients] 2021 Jun 29; Vol. 13 (7). Date of Electronic Publication: 2021 Jun 29.

Multi-omics analysis reveals the influence of genetic and environmental risk factors on developing gut microbiota in infants at risk of celiac disease.

Autor: Leonard MM; Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Harvard Medical School, Boston, MA, USA.; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Boston, USA.; Harvard Medical School, Boston, MA, USA.; Celiac Research Program, Harvard Medical School, Boston, MA, USA., Karathia H; CosmosID Inc., Rockville, MD, USA., Pujolassos M; Theoreo srl, University of Salerno, Montecorvino Pugliano, Italy., Troisi J; Theoreo srl, University of Salerno, Montecorvino Pugliano, Italy.; Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Salerno, Italy.; European Biomedical Research Institute of Salerno (EBRIS), Via S. De Renzi, 50, 84125, Salerno, Italy., Valitutti F; European Biomedical Research Institute of Salerno (EBRIS), Via S. De Renzi, 50, 84125, Salerno, Italy.; Pediatric Unit, Maternal and Child Health Department, AOU San Giovanni di Dio e Ruggi d'Aragona, Salerno, Italy., Subramanian P; CosmosID Inc., Rockville, MD, USA., Camhi S; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Boston, USA.; Celiac Research Program, Harvard Medical School, Boston, MA, USA., Kenyon V; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Boston, USA.; Celiac Research Program, Harvard Medical School, Boston, MA, USA., Colucci A; Theoreo srl, University of Salerno, Montecorvino Pugliano, Italy.; Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Salerno, Italy., Serena G; Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Harvard Medical School, Boston, MA, USA.; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Boston, USA.; Harvard Medical School, Boston, MA, USA.; Celiac Research Program, Harvard Medical School, Boston, MA, USA., Cucchiara S; Pediatric Gastroenterology, Sapienza University of Rome, Rome, Italy., Montuori M; Pediatric Gastroenterology, Sapienza University of Rome, Rome, Italy., Malamisura B; Pediatric Unit, Maternal and Child Health Department, AOU San Giovanni di Dio e Ruggi d'Aragona, Pole of Cava de' Tirreni, Salerno, Italy., Francavilla R; Pediatric Gastroenterology, University of Bari, Bari, Italy., Elli L; Center for Prevention and Diagnosis of Celiac Disease Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Fanelli B; CosmosID Inc., Rockville, MD, USA., Colwell R; CosmosID Inc., Rockville, MD, USA.; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD, USA., Hasan N; CosmosID Inc., Rockville, MD, USA., Zomorrodi AR; Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Harvard Medical School, Boston, MA, USA. azomorrodi@mgh.harvard.edu.; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Boston, USA. azomorrodi@mgh.harvard.edu.; Harvard Medical School, Boston, MA, USA. azomorrodi@mgh.harvard.edu.; Celiac Research Program, Harvard Medical School, Boston, MA, USA. azomorrodi@mgh.harvard.edu., Fasano A; Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Harvard Medical School, Boston, MA, USA. afasano@mgh.harvard.edu.; Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Boston, USA. afasano@mgh.harvard.edu.; Harvard Medical School, Boston, MA, USA. afasano@mgh.harvard.edu.; Celiac Research Program, Harvard Medical School, Boston, MA, USA. afasano@mgh.harvard.edu.; European Biomedical Research Institute of Salerno (EBRIS), Via S. De Renzi, 50, 84125, Salerno, Italy. afasano@mgh.harvard.edu.

Publikováno v: Microbiome [Microbiome] 2020 Sep 11; Vol. 8 (1), pp. 130. Date of Electronic Publication: 2020 Sep 11.

Synthetic Ecology of Microbes: Mathematical Models and Applications.

Autor: Zomorrodi AR; Bioinformatics Program, Boston University, Boston, MA., Segrè D; Bioinformatics Program, Boston University, Boston, MA; Department of Biology, Boston University, Boston, MA; Department of Biomedical Engineering, Boston University, Boston, MA. Electronic address: dsegre@bu.edu.

Publikováno v: Journal of molecular biology [J Mol Biol] 2016 Feb 27; Vol. 428 (5 Pt B), pp. 837-61. Date of Electronic Publication: 2015 Nov 11.