Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Zoltan Spolarics"'
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Most preclinical treatments for sepsis failed in clinical trials in part because the experimental models of sepsis were performed on healthy animals that do not mimic septic patients. Here, we report that experimental diabetes worsens glycemia, infla
Externí odkaz:
https://doaj.org/article/7a7bb438ac9c4350a6bc18b5a5cd9509
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Females have a longer lifespan and better general health than males. Considerable number of studies also demonstrated that, after trauma and sepsis, females present better outcomes as compared to males indicating sex-related differences in the innate
Externí odkaz:
https://doaj.org/article/b01b8cb08a414a88868b931e3f011401
Publikováno v:
Shock. 58:179-188
Sex-related outcome differences in trauma remain controversial. The mechanisms causing sex-biased outcomes are likely to have hormonal and genetic components, in which X-linked genetic polymorphisms may play distinct roles because of X-linked inherit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5498a2c54a4ec1f6e0334f31df74e052
https://doi.org/10.1097/shk.0000000000001966
https://doi.org/10.1097/shk.0000000000001966
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1179:134-140
Glucose use and pentose cycle activity were determined in freshly isolated rat Kupffer cells 3 h after an i.v. injection of Escherichia coli endotoxin (0.1 mg/kg body weight), by using [1-14C], [6-14C] and [2-3H]glucose. Endotoxin treatment in vivo c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db1ef7a2af41e76905237f8919fdcc4
https://doi.org/10.1016/0167-4889(93)90134-b
https://doi.org/10.1016/0167-4889(93)90134-b
Publikováno v:
Biochemical and Biophysical Research Communications. 193:1211-1215
Expression of various glucose transporter isoforms was studied in hepatic cells from fasted rats 3h after an injection of E. coli LPS (1mg/kg bw., i.v.). Glucose transporter isoform content of plasma membranes from hepatic cells was determined by wes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b5bfdb5223c921993d3cca99b30e22
https://doi.org/10.1006/bbrc.1993.1754
https://doi.org/10.1006/bbrc.1993.1754
Autor:
John J. Spitzer, C. Wayne Smith, Hartmut Jaeschke, Zoltan Spolarics, Abraham P. Bautista, Anwar Farhood
Publikováno v:
Hepatology. 17:915-923
The role of neutrophil CD11b/CD18 (Mac-1) adhesion proteins in the pathogenesis of hepatic reperfusion injury was investigated in an experimental model. Male Fischer rats were treated with a CD11b monoclonal antibody or an isotype-matched IgM control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c00f715fec85f505b6ad702b89418613
https://doi.org/10.1002/hep.1840170523
https://doi.org/10.1002/hep.1840170523
Publikováno v:
Hepatology. 17:924-931
Neutrophils and macrophages play an important role in the body's microbicidal defense and have been implicated in the induction of tissue injury in reperfusion, endotoxemia and septic shock. Cellular host defense is accompanied by enhanced glucose us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17c13809db5a98689cd5dc23ed4b73bd
https://doi.org/10.1002/hep.1840170524
https://doi.org/10.1002/hep.1840170524
Autor:
Zoltan Spolarics, John J. Spitzer, Gregory J. Bagby, Agnes Schuler, Charles H. Lang, Steve Nelson
Publikováno v:
Journal of Leukocyte Biology. 51:360-365
This study investigates the in vivo glucose utilization of various immune-competent cells after an intra-arterial injection of a nonlethal dose (30 μg/kg body weight) of murine recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF). I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1610475e155778efa82e1e2473f223
https://doi.org/10.1002/jlb.51.4.360
https://doi.org/10.1002/jlb.51.4.360
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 261:G891-G895
Tumor necrosis factor (TNF) has been implicated as one of the mediators of the immunologic and metabolic changes in endotoxemia. Under adverse conditions, TNF can also be cytotoxic, and its effects can ultimately contribute to organ failure. This stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b3cb2c74dbc119b1184eb81e92c1238
https://doi.org/10.1152/ajpgi.1991.261.6.g891
https://doi.org/10.1152/ajpgi.1991.261.6.g891
Publikováno v:
Biochemical Journal. 278:515-519
Alterations of glucose metabolism and the oxidation of glutamine and palmitate were studied, by using specifically labelled substrates, in freshly isolated Kupffer cells and hepatic endothelial cells after infusion in vivo of human recombinant tumour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0c13580184647bf59fdaee2f936fcf
https://doi.org/10.1042/bj2780515
https://doi.org/10.1042/bj2780515