Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Zoltán Greff"'
Autor:
Johannes Brägelmann, Marcel A. Dammert, Felix Dietlein, Johannes M. Heuckmann, Axel Choidas, Stefanie Böhm, André Richters, Debjit Basu, Verena Tischler, Carina Lorenz, Peter Habenberger, Zhizhou Fang, Sandra Ortiz-Cuaran, Frauke Leenders, Jan Eickhoff, Uwe Koch, Matthäus Getlik, Martin Termathe, Muhammad Sallouh, Zoltán Greff, Zoltán Varga, Hyatt Balke-Want, Christopher A. French, Martin Peifer, H. Christian Reinhardt, László Örfi, György Kéri, Sascha Ansén, Lukas C. Heukamp, Reinhard Büttner, Daniel Rauh, Bert M. Klebl, Roman K. Thomas, Martin L. Sos
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2833-2845 (2017)
Kinase inhibitors represent the backbone of targeted cancer therapy, yet only a limited number of oncogenic drivers are directly druggable. By interrogating the activity of 1,505 kinase inhibitors, we found that BRD4-NUT-rearranged NUT midline carcin
Externí odkaz:
https://doaj.org/article/65260813004b4d5e8d198b9f59d2baa6
Autor:
Attila Varga, Pál Gyulavári, Zoltán Greff, Krisztina Futosi, Tamás Németh, Laura Simon-Szabó, Krisztina Kerekes, Csaba Szántai-Kis, Diána Brauswetter, Márton Kokas, Gábor Borbély, Anna Erdei, Attila Mócsai, György Kéri, Tibor Vántus
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144792 (2015)
Externí odkaz:
https://doaj.org/article/55ac64e255ec4adb9ce3d6c16ecbc5c2
Autor:
Attila Varga, Pál Gyulavári, Zoltán Greff, Krisztina Futosi, Tamás Németh, Laura Simon-Szabó, Krisztina Kerekes, Csaba Szántai-Kis, Diána Brauswetter, Márton Kokas, Gábor Borbély, Anna Erdei, Attila Mócsai, György Kéri, Tibor Vántus
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124234 (2015)
Emerging evidence suggests that the vascular endothelial growth factor receptor 2 (VEGFR2) and protein kinase D1 (PKD1) signaling axis plays a critical role in normal and pathological angiogenesis and inflammation related processes. Despite all effor
Externí odkaz:
https://doaj.org/article/e59f67d585014cf3805d900a5d2cab4d
Autor:
Henrik Daub, Josef Wissing, György Kéri, Matt Cotten, Bert Klebl, Stefan Müller, Martina Weber, Alexander Kurtenbach, Stephanie Blencke, Klaus Godl, Zoltán Greff, Dirk Brehmer
Supplementary Methods and Figure from Cellular Targets of Gefitinib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c7a36d033024c906dd8d464db7ab66
https://doi.org/10.1158/0008-5472.22361673.v1
https://doi.org/10.1158/0008-5472.22361673.v1
Autor:
Henrik Daub, Josef Wissing, György Kéri, Matt Cotten, Bert Klebl, Stefan Müller, Martina Weber, Alexander Kurtenbach, Stephanie Blencke, Klaus Godl, Zoltán Greff, Dirk Brehmer
Supplementary Table 2 from Cellular Targets of Gefitinib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fef01c4943db660c7fa2c6553b62f51
https://doi.org/10.1158/0008-5472.22333051.v1
https://doi.org/10.1158/0008-5472.22333051.v1
Autor:
Henrik Daub, Josef Wissing, György Kéri, Matt Cotten, Bert Klebl, Stefan Müller, Martina Weber, Alexander Kurtenbach, Stephanie Blencke, Klaus Godl, Zoltán Greff, Dirk Brehmer
Supplementary Table 1 from Cellular Targets of Gefitinib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3881c8958e642fecbb5e0f473b8a051c
https://doi.org/10.1158/0008-5472.22361670
https://doi.org/10.1158/0008-5472.22361670
Autor:
Henrik Daub, Josef Wissing, György Kéri, Matt Cotten, Bert Klebl, Stefan Müller, Martina Weber, Alexander Kurtenbach, Stephanie Blencke, Klaus Godl, Zoltán Greff, Dirk Brehmer
Targeted inhibition of protein kinases with small molecule drugs has evolved into a viable approach for anticancer therapy. However, the true selectivity of these therapeutic agents has remained unclear. Here, we used a proteomic method to profile th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46df888bca05c3069e009f3f92364397
https://doi.org/10.1158/0008-5472.c.6493059.v1
https://doi.org/10.1158/0008-5472.c.6493059.v1
Autor:
Felix Dietlein, Roman K. Thomas, Martin Peifer, Daniel Rauh, Zoltán Varga, Johannes M. Heuckmann, Axel Choidas, Johannes Brägelmann, Jan Eickhoff, Carina Lorenz, Hyatt Balke-Want, György Kéri, Zhizhou Fang, Stefanie Böhm, Zoltán Greff, Muhammad Sallouh, Martin Termathe, Reinhard Büttner, Debjit Basu, Christopher A. French, Uwe Koch, Frauke Leenders, André Richters, Martin L. Sos, Verena Tischler, Bert Klebl, Sascha Ansén, Peter Habenberger, Laszlo Orfi, Matthäus Getlik, Sandra Ortiz-Cuaran, Marcel A. Dammert, Lukas C. Heukamp, H. Christian Reinhardt
Publikováno v:
Cell Reports
Cell Reports, Vol 20, Iss 12, Pp 2833-2845 (2017)
Cell Reports, Vol 20, Iss 12, Pp 2833-2845 (2017)
Summary Kinase inhibitors represent the backbone of targeted cancer therapy, yet only a limited number of oncogenic drivers are directly druggable. By interrogating the activity of 1,505 kinase inhibitors, we found that BRD4-NUT-rearranged NUT midlin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbfadea6b1ad3b4323f2fa27e4edbd58
http://europepmc.org/articles/PMC5622049
http://europepmc.org/articles/PMC5622049
Autor:
Péter Bánhegyi, Zoltán Greff, Axel Ullrich, Tibor Vántus, László Őrfi, József Mandl, György Kéri, Laura Simon-Szabó, Csaba Szántai-Kis, Sándor Boros, Márton Kokas, Lilian Zsákai, Miklós Csala, Gábor Bánhegyi, István Vályi-Nagy
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:424-428
Activation of various interacting stress kinases, particularly the c-Jun N-terminal kinases (JNK), and a concomitant phosphorylation of insulin receptor substrate 1 (IRS-1) at serine 307 play a central role both in insulin resistance and in β-cell d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6a1a75d264d9775c6078b36286ed7b
https://doi.org/10.1016/j.bmcl.2015.11.099
https://doi.org/10.1016/j.bmcl.2015.11.099
Autor:
János Pató, Stewart T. Cole, Claudia Sala, Ruben C. Hartkoorn, Andrej Benjak, Stefanie Boy-Röttger, István Szabadkai, Zoltán Greff, László Őrfi, György Kéri, Jan Rybniker, Ming Zhang, Anthony Vocat, Rita Székely, Jeffrey M. Chen
Publikováno v:
Cell host & microbe
Europe PubMed Central
Europe PubMed Central
SummaryMycobacterium tuberculosis (Mtb) requires protein secretion systems like ESX-1 for intracellular survival and virulence. The major virulence determinant and ESX-1 substrate, EsxA, arrests phagosome maturation and lyses cell membranes, resultin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ed697d555f95abb1a5ed71f2a93baf
https://doi.org/10.1016/j.chom.2014.09.008
https://doi.org/10.1016/j.chom.2014.09.008