Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Zoltán V. Varga"'
Autor:
Brachyahu M. Kestecher, Krisztina Németh, Sayam Ghosal, Nabil V. Sayour, Tamás G. Gergely, Bernadett R. Bodnár, András I. Försönits, Barbara W. Sódar, Johannes Oesterreicher, Wolfgang Holnthoner, Zoltán V. Varga, Zoltán Giricz, Péter Ferdinandy, Edit I. Buzás, Xabier Osteikoetxea
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Aims The association and co-isolation of low-density lipoproteins (LDL) and extracellular vesicles (EVs) have been shown in blood plasma. Here we explore this relationship to better understand the role of EVs in atherogenesis. Methods and re
Externí odkaz:
https://doaj.org/article/96be4664a30a4f128e0112c34002fecd
Autor:
Eric Schoger, Federico Bleckwedel, Giulia Germena, Cheila Rocha, Petra Tucholla, Izzatullo Sobitov, Wiebke Möbius, Maren Sitte, Christof Lenz, Mostafa Samak, Rabea Hinkel, Zoltán V. Varga, Zoltán Giricz, Gabriela Salinas, Julia C. Gross, Laura C. Zelarayán
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/211e5acd4e8f40e392b605c7e6a15534
Autor:
Szilamér Ferenczi, Fruzsina Mogor, Peter Takacs, Tamas Kovacs, Viktoria E. Toth, Zoltán V. Varga, Krisztina Kovács, Zoltan Lohinai, Koppány Csaba Vass, Nandor Nagy, David Dora
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Previously, the presence of a blood-myenteric plexus barrier and its disruption was reported in experimentally induced colitis via a macrophage-dependent process. The aim of this study is to reveal how myenteric barrier disruption and subseq
Externí odkaz:
https://doaj.org/article/886c13f3f37d4de5af40aeac9394aa98
Autor:
Eric Schoger, Federico Bleckwedel, Giulia Germena, Cheila Rocha, Petra Tucholla, Izzatullo Sobitov, Wiebke Möbius, Maren Sitte, Christof Lenz, Mostafa Samak, Rabea Hinkel, Zoltán V. Varga, Zoltán Giricz, Gabriela Salinas, Julia C. Gross, Laura C. Zelarayán
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Aberrant Wnt activation has been reported in failing cardiomyocytes. Here we present single cell transcriptome profiling of hearts with inducible cardiomyocyte-specific Wnt activation (β-catΔex3) as well as with compensatory and failing hy
Externí odkaz:
https://doaj.org/article/3e9a30bbd37f427087c641a482573fde
Autor:
Dániel Kucsera, Viktória E. Tóth, Nabil V. Sayour, Tamás Kovács, Tamás G. Gergely, Mihály Ruppert, Tamás Radovits, Alexandra Fábián, Attila Kovács, Béla Merkely, Péter Ferdinandy, Zoltán V. Varga
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Interleukin-1β (IL-1β) is a key mediator of non-alcoholic steatohepatitis (NASH), a chronic liver disease, and of systemic inflammation-driven aging. IL-1β contributes to cardio-metabolic decline, and may promote hepatic oncogenic transfo
Externí odkaz:
https://doaj.org/article/4c0e61863a41496687dce854be03e766
Autor:
Szilvia Kugler, Zsófia Onódi, Mihály Ruppert, Alex Ali Sayour, Attila Oláh, Kálmán Benke, Péter Ferdinandy, Béla Merkely, Tamás Radovits, Zoltán V. Varga
Publikováno v:
ESC Heart Failure, Vol 9, Iss 4, Pp 2747-2752 (2022)
Abstract Aims Inflammatory pathways are increasingly recognized as an important factor in the pathophysiology of both heart failure (HF) and atrial fibrillation (AF). However, there is no data about inflammation‐related histological and molecular a
Externí odkaz:
https://doaj.org/article/e1a54b56821149328c852c25fefcfcea
Autor:
Jacqueline Heger, Stefan Partsch, Claudia Harjung, Zoltán V. Varga, Tamás Baranyai, Johannes Weiß, Lea Kremer, Fabian Locquet, Przemyslaw Leszek, Bence Ágg, Bettina Benczik, Péter Ferdinandy, Rainer Schulz, Gerhild Euler
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 401 (2023)
Cardiac hypertrophy resulting from sympathetic nervous system activation triggers the development of heart failure. The transcription factor Y-box binding protein 1 (YB-1) can interact with transcription factors involved in cardiac hypertrophy and ma
Externí odkaz:
https://doaj.org/article/43a811068dde42149ee976eccc024c5a
Autor:
Nabil V. Sayour, Viktória É. Tóth, Regina N. Nagy, Imre Vörös, Tamás G. Gergely, Zsófia Onódi, Noémi Nagy, Csaba Bödör, Barnabás Váradi, Mihály Ruppert, Tamás Radovits, Federico Bleckwedel, Laura C. Zelarayán, Pal Pacher, Bence Ágg, Anikó Görbe, Péter Ferdinandy, Zoltán V. Varga
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13826 (2023)
The identification of novel drug targets is needed to improve the outcomes of heart failure (HF). G-protein-coupled receptors (GPCRs) represent the largest family of targets for already approved drugs, thus providing an opportunity for drug repurposi
Externí odkaz:
https://doaj.org/article/cf0ec70700ff485780b6aa30bc1f3382
Autor:
Zsófia Onódi, Petra Lujza Szabó, Dániel Kucsera, Péter Pokreisz, Christopher Dostal, Karlheinz Hilber, Gavin Y. Oudit, Bruno K. Podesser, Péter Ferdinandy, Zoltán V. Varga, Attila Kiss
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8497 (2023)
Duchenne muscular dystrophy (DMD) is characterized by wasting of muscles that leads to difficulty moving and premature death, mainly from heart failure. Glucocorticoids are applied in the management of the disease, supporting the hypothesis that infl
Externí odkaz:
https://doaj.org/article/2d53d14d1dab4458ab0007fbfeed3448
Autor:
David Á. Karádi, Anna Rita Galambos, Péter P. Lakatos, Joost Apenberg, Sarah K. Abbood, Mihály Balogh, Kornél Király, Pál Riba, Nariman Essmat, Edina Szűcs, Sándor Benyhe, Zoltán V. Varga, Éva Szökő, Tamás Tábi, Mahmoud Al-Khrasani
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7970 (2023)
Despite the large arsenal of analgesic medications, neuropathic pain (NP) management is not solved yet. Angiotensin II receptor type 1 (AT1) has been identified as a potential target in NP therapy. Here, we investigate the antiallodynic effect of AT1
Externí odkaz:
https://doaj.org/article/f55ea3f921e045958b4c844b98212bbd