Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zoltán Urbányi"'
Autor:
Merle Nebel, Viktor Háda, Zoltán Urbányi, Tamás Schäfer, Róbert Kiss, Helga Hevér, Tanja Stadie, Piroska Kovács, Sonja Klingelhöfer
Publikováno v:
Biodrugs
Background In January 2017, the European Commission approved Terrosa® (company code RGB-10) as one of the first biosimilar medicinal products of teriparatide for the same indications as for the reference medicinal product Forsteo® (Lilly France S.A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb0e2858936d7fa8366cf39f43df655
https://doi.org/10.1007/s40259-019-00386-x
https://doi.org/10.1007/s40259-019-00386-x
Autor:
Zoltán Urbányi
Publikováno v:
Drug Discovery Today: Technologies. 40:1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a755f2577a316c6aaa7acc58049dc8
https://doi.org/10.1016/j.ddtec.2021.10.006
https://doi.org/10.1016/j.ddtec.2021.10.006
Autor:
Zoltán Urbányi
Publikováno v:
Drug discovery today. Technologies. 38
The number of approved and marketed biosimilar monoclonal antibodies has been increasing steeply in recent years in regulated markets. In contrast to small molecular generic drugs, structure and variant profile of biosimilar mAbs are not identical wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65852e401860f59b07c7a5db2a13fe8
https://pubmed.ncbi.nlm.nih.gov/34895635
https://pubmed.ncbi.nlm.nih.gov/34895635
Publikováno v:
Journal of Chromatography B. 1032:224-229
Capillary electrophoresis techniques are widely used in the analytical biotechnology. Different electrophoretic techniques are very adequate tools to monitor size-and charge heterogenities of protein drugs. Method descriptions and development studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15af08c16dde698525fac7a39de69dd
https://doi.org/10.1016/j.jchromb.2016.07.026
https://doi.org/10.1016/j.jchromb.2016.07.026
Autor:
Gábor Szabó, Izabella Obál, Mária A. Deli, László Fábián, Szilvia Veszelka, Csongor S. Ábrahám, Zoltán Urbányi, Judit Laszy, Tamas Pazmany, Laszlo Nemeth
Publikováno v:
European Journal of Microbiology and Immunology. 3:281-289
Serum amyloid P component (SAP), a member of the innate immune system, does not penetrate the brain in physiological conditions; however, SAP is a stabilizing component of the amyloid plaques in neurodegenerative diseases. We investigated the cerebro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5720a20063a2ac49ee8974286368c59
https://doi.org/10.1556/eujmi.3.2013.4.8
https://doi.org/10.1556/eujmi.3.2013.4.8
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 114
Capillary isoelectric focusing (cIEF) is a basic and highly accurate routine analytical tool to prove identity of protein drugs in quality control (QC) and release tests in biopharmaceutical industries. However there are some “ out-of-the-box ” a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b12748113c9b1b6205911ef64366457
https://pubmed.ncbi.nlm.nih.gov/26025812
https://pubmed.ncbi.nlm.nih.gov/26025812
Publikováno v:
Neurochemistry International. 46:471-477
Serum amyloid P component, a member of pentraxin serum protein family, has been suggested to contribute to the progression of neurodegeneration including Alzheimer's disease by binding to beta-amyloid fibrils leading to an increased stability of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7172fb20eb43ad73716e8c25d80517
https://doi.org/10.1016/j.neuint.2004.12.001
https://doi.org/10.1016/j.neuint.2004.12.001
Autor:
Ngo Thi Khue Dung, Mária A. Deli, Zoltán Urbányi, Izabella Obál, Csongor S. Ábrahám, Szilvia Veszelka, Tamas Pazmany, Laszlo Nemeth, Gábor Szabó
Publikováno v:
Neuroscience Letters. 352:57-60
Endotoxin challenge leads to septic shock, multi-organ failure and death in mice. Permeability of the blood-brain barrier (BBB) is increased by endotoxemia. Serum amyloid P component (SAP) is a lipopolysaccharide (LPS)-binding protein that can modula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d572c6a916228fe7922e105644aee9fc
https://doi.org/10.1016/j.neulet.2003.08.028
https://doi.org/10.1016/j.neulet.2003.08.028
Autor:
Tamas Pazmany, Erzsébet Tóth, Éva Mekes, Zoltán Urbányi, Miklós Sass, Thomas B. Tomasi, Lajos László
Publikováno v:
Brain Research. 988:69-77
Previously we have reported serum amyloid P component (SAP) induced cell death in cerebro-cortical cultures of rat brain. In this paper we studied the types of target cells and the molecular mechanism of SAP-induced cell death. Immuno-electron and li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778e5b428766d9638766ab57f70bed51
https://doi.org/10.1016/s0006-8993(03)03345-6
https://doi.org/10.1016/s0006-8993(03)03345-6
Autor:
Tibor Acs, Zoltán Urbányi, Judit Ovádi, Beáta G. Vértessy, János Kovács, Ferenc Orosz, Péter Löw, Tibor Keve
Publikováno v:
British Journal of Pharmacology. 121:947-954
1. KAR-2 (3"-(beta-chloroethyl)-2",4"-dioxo-3,5"-spiro-oxazolidino- 4-deacetoxy-vinblastine), is a bis-indol derivative; catharantine is coupled with the vindoline moiety which contains a substituted oxazolidino group. Our binding studies showed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07cfe3ce67b02600827efc599b496ea0
https://doi.org/10.1038/sj.bjp.0701189
https://doi.org/10.1038/sj.bjp.0701189