Výsledky vyhledávání - "Zoltán Urbán"

Akademický článek

Applicability of MDR1 Overexpressing Abcb1KO-MDCKII Cell Lines for Investigating In Vitro Species Differences and Brain Penetration Prediction

Autor: Emőke Sóskuti, Nóra Szilvásy, Csilla Temesszentandrási-Ambrus, Zoltán Urbán, Olivér Csíkvári, Zoltán Szabó, Gábor Kecskeméti, Éva Pusztai, Zsuzsanna Gáborik

Publikováno v: Pharmaceutics, Vol 16, Iss 6, p 736 (2024)

Implementing the 3R initiative to reduce animal experiments in brain penetration prediction for CNS-targeting drugs requires more predictive in vitro and in silico models. However, animal studies are still indispensable to obtaining brain concentrati

Externí odkaz: https://doaj.org/article/a94321fbe560458d94a6ee7221ab5362

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Morphology and synaptic input of substance P receptor-immunoreactive interneurons in control and epileptic human hippocampus

Autor: Lucia Wittner, Tamás F. Freund, Kinga Tóth, Zoltán Urbán, Ryuichi Shigemoto, György Buzsáki, Zsófia Maglóczky, Werner Doyle

Publikováno v: Neuroscience. 144(2)

Substance P (SP) is known to be a peptide that facilitates epileptic activity of principal cells in the hippocampus. Paradoxically, in other models, it was found to be protective against seizures by activating substance P receptor (SPR)-expressing in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097aabeb4284ba7f4b84f622624ec44b
https://pubmed.ncbi.nlm.nih.gov/17097238

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