Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Zoltán Dezso"'
Autor:
Adaikkalam Vellaichamy, Zoltán Dezso, Lellean JeBailey, Arul M Chinnaiyan, Arun Sreekumar, Alexey I Nesvizhskii, Gilbert S Omenn, Andrej Bugrim
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10936 (2010)
The problem of prostate cancer progression to androgen independence has been extensively studied. Several studies systematically analyzed gene expression profiles in the context of biological networks and pathways, uncovering novel aspects of prostat
Externí odkaz:
https://doaj.org/article/19a817bc02e64b12a5fd96a0f4ce7600
Autor:
Michael Cunningham, Danielle Pins, Zoltán Dezső, Maricel Torrent, Aparna Vasanthakumar, Abhishek Pandey
Publikováno v:
Journal of Cheminformatics, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract The identification of human proteins that are amenable to pharmacologic modulation without significant off-target effects remains an important unsolved challenge. Computational methods have been devised to identify features which distinguish
Externí odkaz:
https://doaj.org/article/7c390b00d7f64e94b26921de4ddbecdc
Autor:
Bridget Riley-Gillis, Shirng-Wern Tsaih, Emily King, Sabrina Wollenhaupt, Jonas Reeb, Amy R. Peck, Kelsey Wackman, Angela Lemke, Hallgeir Rui, Zoltan Dezso, Michael J. Flister
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107576- (2023)
Summary: Heritability in the immune tumor microenvironment (iTME) has been widely observed yet remains largely uncharacterized. Here, we developed a machine learning approach to map iTME modifiers within loci from genome-wide association studies (GWA
Externí odkaz:
https://doaj.org/article/c7ce89221a684130966eeb85e931f3cc
Autor:
Zoltán Dezső, Michele Ceccarelli
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background The selection and prioritization of drug targets is a central problem in drug discovery. Computational approaches can leverage the growing number of large-scale human genomics and proteomics data to make in-silico target identific
Externí odkaz:
https://doaj.org/article/e502cfe65ff94bc1b85a67d4c10ffb37
Akademický článek
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Autor:
Sergei I. Agoulnik, Zoltan Dezso, Bryan E. Hoffman, Natalie C. Twine, Stephen M. Jackson, Daniel J. O'Shannessy, Elizabeth B. Somers
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 7, Pp 13687-13703 (2013)
Folate receptor alpha (FOLR1/FRA) is reported to be overexpressed in epithelial ovarian cancers (EOC), especially the serous histotype. Further, while dysregulation of the folate-dependent 1-carbon cycle has been implicated in tumorogenesis, little i
Externí odkaz:
https://doaj.org/article/706e06d839d7477c90d137d87c35c527
Autor:
Pavan Kumar, Zoltan Dezso, Crystal MacKenzie, Judy Oestreicher, Sergei Agoulnik, Michael Byrne, Francois Bernier, Mamoru Yanagimachi, Ken Aoshima, Yoshiya Oda
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69807 (2013)
A minimally invasive diagnostic assay for early detection of Alzheimer's disease (AD) is required to select optimal patient groups in clinical trials, monitor disease progression and response to treatment, and to better plan patient clinical care. Bl
Externí odkaz:
https://doaj.org/article/d506b339c5284f2390f8cbdf863dd996