Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Zoi, Alexopoulou"'
Autor:
Brad A. Sutherland, Gina Hadley, Zoi Alexopoulou, Tiffany A. Lodge, Ain A. Neuhaus, Yvonne Couch, Nareg Kalajian, Karl J. Morten, Alastair M. Buchan
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Age-related neuronal dysfunction can be overcome by circulating factors present in young blood. Growth differentiation factor-11 (GDF-11), a systemic factor that declines with age, can reverse age-related dysfunction in brain, heart and skeletal musc
Externí odkaz:
https://doaj.org/article/fa3727ac47e4426391dce0006722206a
Publikováno v:
Clinical Pharmacology & Therapeutics. 111:835-839
Use of early predictive biomarkers of neurodegenerative disease in phase I clinical trials may improve the translation of novel drug therapies from preclinical development through late-stage studies. This article provides a categorical summary of pro
Autor:
Vassiliki Kotoula, Sotiris Lakis, Ioannis S Vlachos, Eleni Giannoulatou, Flora Zagouri, Zoi Alexopoulou, Helen Gogas, Dimitrios Pectasides, Gerasimos Aravantinos, Ioannis Efstratiou, George Pentheroudakis, Kyriaki Papadopoulou, Kyriakos Chatzopoulos, Pavlos Papakostas, Maria Sotiropoulou, Irene Nicolaou, Evangelia Razis, Amanda Psyrri, Paris Kosmidis, Christos Papadimitriou, George Fountzilas
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163138 (2016)
Stromal tumor infiltrating lymphocytes (TILs) density is an outcome predictor in triple-negative breast cancer (TNBC). Herein we asked whether TILs are related to coding mutation load and to the chemical class of the resulting mutated amino acids, i.
Externí odkaz:
https://doaj.org/article/c22d07cc557b4f04882d649c66ff7d85
Autor:
Flora Stavridi, Konstantine T Kalogeras, Kyriaki Pliarchopoulou, Ralph M Wirtz, Zoi Alexopoulou, Flora Zagouri, Elke Veltrup, Eleni Timotheadou, Helen Gogas, Angelos Koutras, Georgios Lazaridis, Christos Christodoulou, George Pentheroudakis, Apostolos Laskarakis, Petroula Arapantoni-Dadioti, Anna Batistatou, Maria Sotiropoulou, Gerasimos Aravantinos, Pavlos Papakostas, Paris Kosmidis, Dimitrios Pectasides, George Fountzilas
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164013 (2016)
Early breast cancer is a heterogeneous disease, and, therefore, prognostic tools have been developed to evaluate the risk for distant recurrence. In the present study, we sought to develop a risk for recurrence score (RRS) based on mRNA expression of
Externí odkaz:
https://doaj.org/article/32bf2fe4b2c74acaa675ad5c50cc86ef
Autor:
Vassiliki Kotoula, Aggeliki Lyberopoulou, Kyriaki Papadopoulou, Elpida Charalambous, Zoi Alexopoulou, Chryssa Gakou, Sotiris Lakis, Eleftheria Tsolaki, Konstantinos Lilakos, George Fountzilas
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128818 (2015)
Massively parallel sequencing (MPS) holds promise for expanding cancer translational research and diagnostics. As yet, it has been applied on paraffin DNA (FFPE) with commercially available highly multiplexed gene panels (100s of DNA targets), while
Externí odkaz:
https://doaj.org/article/aee2dfaae82049d791365de507171c0d
Autor:
George Papaxoinis, Vassiliki Kotoula, Zoi Alexopoulou, Konstantine T Kalogeras, Flora Zagouri, Eleni Timotheadou, Helen Gogas, George Pentheroudakis, Christos Christodoulou, Angelos Koutras, Dimitrios Bafaloukos, Gerasimos Aravantinos, Pavlos Papakostas, Elpida Charalambous, Kyriaki Papadopoulou, Ioannis Varthalitis, Ioannis Efstratiou, Thomas Zaramboukas, Helen Patsea, Chrisoula D Scopa, Maria Skondra, Paris Kosmidis, Dimitrios Pectasides, George Fountzilas
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140293 (2015)
The PI3K-AKT pathway is frequently activated in breast cancer. PIK3CA mutations are most frequently found in the helical (exon 9) and kinase (exon 20) domains of this protein. The aim of the present study was to examine the role of different types of
Externí odkaz:
https://doaj.org/article/148d1ad876ed40fd8096f0ed1713fb3a
Publikováno v:
Neuroscience Letters. 706:223-230
Introduction: Hamartin, a component of the tuberous sclerosis complex (TSC) that actively inhibits the mammalian target of rapamycin (mTOR), may mediate the endogenous resistance of Cornu Ammonis 3 (CA3) hippocampal neurons following global cerebral
Autor:
Vassiliki Kotoula, Mattheos Bobos, Zoi Alexopoulou, Christos Papadimitriou, Kyriaki Papadopoulou, Elpida Charalambous, Eleftheria Tsolaki, Grigorios Xepapadakis, Irene Nicolaou, Irene Papaspirou, Gerasimos Aravantinos, Christos Christodoulou, Ioannis Efstratiou, Helen Gogas, George Fountzilas
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103707 (2014)
BACKGROUND: HER2 and TOP2A gene status are assessed for diagnostic and research purposes in breast cancer with fluorescence in situ hybridization (FISH). However, FISH probes do not target only the annotated gene, while chromosome 17 (chr17) is among
Externí odkaz:
https://doaj.org/article/1c97f2dd901546c7920fc2c29acc59b9
Autor:
Zoi Alexopoulou, Alastair M. Buchan, Tiffany A. Lodge, Nareg Kalajian, Gina Hadley, Brad A. Sutherland, Karl J. Morten, Ain A Neuhaus, Yvonne Couch
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Age-related neuronal dysfunction can be overcome by circulating factors present in young blood. Growth differentiation factor-11 (GDF-11), a systemic factor that declines with age, can reverse age-related dysfunction in brain, heart and skeletal musc
Autor:
Fiona H. Marshall, Maya A. Hanspal, Vishal Sahni, Jina E. Swartz, Zoi Alexopoulou, Sébastien Gillotin, Tjaša Lepko
Publikováno v:
Ageing Research Reviews. 71:101447
Deficits in adult neurogenesis may contribute to the aetiology of many neurodevelopmental, psychiatric and neurodegenerative diseases. Genetic ablation of neurogenesis provides proof of concept that adult neurogenesis is required to sustain complex a