Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Zohreh Abolfathi"'
Autor:
Jordi Ortuño, Ann Lévesque, Alex Torns, Rita Neves, Susana Marta Almeida, Zohreh Abolfathi, Ana Cristina Franco Spínola, Augusto Filipe
Publikováno v:
Arzneimittelforschung. 60:273-281
These studies were conducted in order to assess the bioequivalence of two film-coated formulations containing 250 mg and 1000 mg of valacyclovir (INN: valaciclovir; CAS 124832-26-4), which is the L-valyl ester and a pro-drug of the antiviral drug acy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e15bf0de5e4b572a60d23504318a29a
https://doi.org/10.1055/s-0031-1296285
https://doi.org/10.1055/s-0031-1296285
Autor:
Zohreh Abolfathi, A. C. Franco Spinola, Mercedes Yritia, Rita Neves, Augusto Filipe, D. Anctil, Susana Marta Almeida
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 47:627-637
This study was conducted in order to compare the bioavailability of two capsule formulations containing 15 mg of sibutramine, N-{1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}-N,N-dimethylamine hydrochloride monohydrate, 84485-00-7 CAS registry numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6edd5e7e2a1e46cf6fc85471246575
https://doi.org/10.5414/cpp47627
https://doi.org/10.5414/cpp47627
Publikováno v:
Xenobiotica. 33:13-25
1. Mexiletine is extensively metabolized in man by C- and N-oxidation and the aim of the present study was to characterize major cytochrome P450 enzyme(s) involved in the formation of N-hydroxymexiletine. 2. Incubations with genetically engineered mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9868c1bca87eec594e072772c4762bd8
https://doi.org/10.1080/0049825021000017948
https://doi.org/10.1080/0049825021000017948
Autor:
Zohreh Abolfathi, Yechiel Golander, John L. Colaizzi, Eric Masson, Avraham Yacobi, Rakesh Mehta, Steve Zlotnick, Daniel A. Moros, Barrie Levitt, Marc LeBel
Publikováno v:
Clinical Pharmacology & Therapeutics. 65:389-394
Background and Objectives Carbamazepine is among those drugs that have been considered to have a narrow therapeutic plasma concentration range, that is, a narrow therapeutic index. Although the US Food and Drug Administration has approved new generic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6710be48443441359a1839e5092aa81
https://doi.org/10.1016/s0009-9236(99)70132-3
https://doi.org/10.1016/s0009-9236(99)70132-3
Autor:
François St-Maurice, Jacques Turgeon, N-Michelle Robitaille, Line Labbé, Zohreh Abolfathi, Marcel Gilbert
Publikováno v:
Therapeutic Drug Monitoring. 21:191-199
Caffeine consumption is extensive in industrialized countries and its role in drug-drug interactions is often overlooked. CYP1A2, the major cytochrome P450 isoform involved in the metabolism of caffeine, has also been implicated in the formation of N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21cdbf390591284b0d48e03b93d0737
https://doi.org/10.1097/00007691-199904000-00009
https://doi.org/10.1097/00007691-199904000-00009
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 579:366-370
A simple and sensitive high-performance liquid chromatographic procedure for resolution of mexiletine enantiomers has been developed. Proteins from plasma samples containing RS-mexiletine were precipitated with a mixture of barium hydroxide and zinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902ebea8df3068ea9ab66c3fe846843e
https://doi.org/10.1016/0378-4347(92)80406-g
https://doi.org/10.1016/0378-4347(92)80406-g
Autor:
Ajay K. Singla, Stéphanie Gagnon, Raveendra Pai, Tausif Monif, Zohreh Abolfathi, Sudershan Kumar, Nageshwar Rao Thudi, Saleh Hussain
Publikováno v:
Arzneimittel-Forschung. 59(10)
This study was conducted in order to assess the bioequivalence of two different formulations containing 70 mg alendronate sodium (CAS 121268-17-5) under fasted conditions. One hundred twenty-two healthy male volunteers were enrolled in an open label,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d041c2ecbb262d0c54e304c0aa452ee6
https://pubmed.ncbi.nlm.nih.gov/19998580
https://pubmed.ncbi.nlm.nih.gov/19998580
Autor:
Zohreh, Abolfathi, Jean, Couture, François, Vallée, Marc, LeBel, Mario, Tanguay, Eric, Masson
Publikováno v:
Journal of pharmacypharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. 7(3)
The purpose of this study was to characterize the food effect on the pharmacokinetics of sibutramine and its pharmacologically active metabolites.This was an open label, single dose, crossover study completed by six healthy males. A single dose of si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2ab4a794e68fcbacc19099b3d18ed81
https://pubmed.ncbi.nlm.nih.gov/15576015
https://pubmed.ncbi.nlm.nih.gov/15576015
Autor:
Marc LeBel, Derek Ganes, Avraham Yacobi, Yechiel Golander, Eric Masson, Daniel A. Moros, Tamar Blumberg, Darlene Doepner, Claude Lapointe, Yoram Cohen, Zohreh Abolfathi, Barrie Levitt
Publikováno v:
Journal of clinical pharmacology. 40(8)
Warfarin is, among drugs, considered to have a narrow therapeutic index for which individual bioequivalence has been suggested. To establish the propriety of “switching,” an individual bioequivalence study involving a replicate-design study and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7ceed7a4af2ec19af7a570cf0b62f7
https://pubmed.ncbi.nlm.nih.gov/10934666
https://pubmed.ncbi.nlm.nih.gov/10934666
Autor:
Thérèse Di Paolo, Zohreh Abolfathi
Publikováno v:
Biochemical pharmacology. 42(11)
The effects of Na + , K + , Mg 2+ and Ca 2+ on the agonist binding sites of D 2 dopamine (DA) receptors were studied in 7315a pituitary tumors. The agonist high and low affinity states of the D 2 receptors were investigated with apomorphine competiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af6fb87f21dcf53f4cbe21238d2b9b4
https://pubmed.ncbi.nlm.nih.gov/1958234
https://pubmed.ncbi.nlm.nih.gov/1958234