Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Zohar Shipony"'
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100854- (2021)
Summary: ATAC-seq is a versatile, adaptable, and widely adopted technique for mapping open chromatin regions. However, some biological systems, such as primary neurons, present unique challenges to its application. Conventional ATAC-seq would require
Externí odkaz:
https://doaj.org/article/6a71d137cfde4b6c812c6b4c470a196a
Autor:
Eran Blacher, Connie Tsai, Lev Litichevskiy, Zohar Shipony, Chinyere Agbaegbu Iweka, Kai Markus Schneider, Bayarsaikhan Chuluun, H. Craig Heller, Vilas Menon, Christoph A. Thaiss, Katrin I. Andreasson
Publikováno v:
Nat Immunol
Nature Immunology
Nature Immunology
Aging is characterized by an increased vulnerability to infection and the development of inflammatory diseases, such as atherosclerosis, frailty, cancer and neurodegeneration. Here, we find that aging is associated with the loss of diurnally rhythmic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7846330144ae30e7b378c8b3812cdb
https://doi.org/10.1038/s41590-021-01083-0
https://doi.org/10.1038/s41590-021-01083-0
Publikováno v:
Chromatin Accessibility ISBN: 9781071628980
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::288d57674a002c4c6245239da476295e
https://doi.org/10.1007/978-1-0716-2899-7_1
https://doi.org/10.1007/978-1-0716-2899-7_1
Autor:
Samuel H. Kim, Georgi K. Marinov, S. Tansu Bagdatli, Soon Il Higashino, Zohar Shipony, Anshul Kundaje, William J. Greenleaf
Publikováno v:
Chromatin Accessibility ISBN: 9781071628980
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::753ad8d21d24a44f0f5c89b4adc7be2e
https://doi.org/10.1007/978-1-0716-2899-7_11
https://doi.org/10.1007/978-1-0716-2899-7_11
Autor:
Yizhou Zhu, Hayan Lee, Annika K. Weimer, Aaron Horning, Stephanie A. Nevins, Edward D. Esplin, Kristina Paul, Gat Krieger, Zohar Shipony, Meredith Mills, Rozelle Laquindanum, Uri Ladabaum, Roxanne Chiu, Teri Longacre, Jeanne Shen, Ariel Jaimovich, Doron Lipson, Anshul Kundaje, William J. Greenleaf, Christina Curtis, James M. Ford, Michael P. Snyder
Although 3D genome architecture is essential for long-range gene regulation, the significance of distal regulatory chromatin contacts is challenged by recent findings of low correlation between contact propensity and gene expression. To better unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b482fb761c18781417720a3bcc22ae
https://doi.org/10.21203/rs.3.rs-2003187/v1
https://doi.org/10.21203/rs.3.rs-2003187/v1
Autor:
Hayan Lee, Gat Krieger, Tyson Clark, Aziz Khan, Casey Ryan Hanson, Yizhou Zhu, Nasim Bararpour, Aaron M. Horning, Edward D. Esplin, Stephanie Nevins, Annika K. Weimer, Eti Meiri, Shlomit Gilad, Sima Benjamin, Danit Lebanony, Nika Iremadze, Florian Oberstrass, Ariel Jaimovich, William Greenleaf, James M. Ford, Doron Lipson, Zohar Shipony, Michael P. Snyder
Aberrant shifts in DNA methylation have long been regarded as an early marker for cancer onset and progression. To chart DNA methylation changes that occur during the transformation from normal healthy colon tissue to malignant colorectal cancer (CRC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::524874cdb4924472cd9a89e42751dafc
https://doi.org/10.1101/2022.05.30.494076
https://doi.org/10.1101/2022.05.30.494076
Publikováno v:
Methods in Molecular Biology ISBN: 9781071621394
Methods Mol Biol
Methods Mol Biol
A hallmark feature of active cis-regulatory elements (CREs) in eukaryotes is their nucleosomal depletion and, accordingly, higher accessibility to enzymatic treatment. This property has been the basis of a number of sequencing-based assays for genome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2f81fb5735af67ab6e9a34d18709f3
https://doi.org/10.1007/978-1-0716-2140-0_15
https://doi.org/10.1007/978-1-0716-2140-0_15
Autor:
Hamish W King, Robson Capasso, Mark M. Davis, Arwa Kathiria, Lars M. Steinmetz, Zohar Shipony, Kristen L. Wells, Nara Orban, Louisa K. James, William J. Greenleaf, Caleb A. Lareau, Lisa E. Wagar
Publikováno v:
Sci Immunol
The germinal center (GC) response is critical for both effective adaptive immunity and establishing peripheral tolerance by limiting autoreactive B cells. Dysfunction in these processes can lead to defective immune responses to infection or contribut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c102c28d07295fc3ba4a3c68a5c3ba28
https://pubmed.ncbi.nlm.nih.gov/34623901
https://pubmed.ncbi.nlm.nih.gov/34623901
Autor:
Iris Barshack, Yoav Manaster, Camila Avivi, Michal J. Besser, Masha Kolesnikov, Bruria Shalmon, Zohar Shipony, Tali Feferman, Anat Hutzler, Guy Shakhar
Publikováno v:
Cancer Immunology, Immunotherapy. 68:1287-1301
Patchy infiltration of tumors by cytotoxic T cells (CTLs) predicts poorer prognosis for cancer patients. The factors limiting intratumoral CTL dissemination, though, are poorly understood. To study CTL dissemination in tumors, we histologically exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57a8793746ebd739012ae832b1ef633
https://doi.org/10.1007/s00262-019-02361-5
https://doi.org/10.1007/s00262-019-02361-5
Increased ACTL6A Occupancy Within mSWI/SNF Chromatin Remodelers Drives Human Squamous Cell Carcinoma
Autor:
Ann Kuo, Chiung-Ying Chang, Zohar Shipony, William J. Greenleaf, Gerald R. Crabtree, Kyle M. Loh
SummaryMammalian SWI/SNF (BAF) chromatin remodelers play dosage-sensitive roles in many human malignancies and neurologic disorders. The gene encoding the BAF subunit, ACTL6A, is amplified at an early stage in the development of squamous cell carcino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fac65ead7083bd995942fd73a072b7d
https://doi.org/10.1101/2021.03.22.435873
https://doi.org/10.1101/2021.03.22.435873