Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Zohar Manber"'
Autor:
Tamar Evron, Michal Caspi, Michal Kazelnik, Yarden Shor-Nareznoy, Shir Armoza-Eilat, Revital Kariv, Zohar Manber, Ran Elkon, Ella H. Sklan, Rina Rosin-Arbesfeld
Publikováno v:
Oncogenesis, Vol 10, Iss 9, Pp 1-11 (2021)
Abstract The Wnt signaling pathways play fundamental roles during both development and adult homeostasis. Aberrant activation of the canonical Wnt signal transduction pathway is involved in many diseases including cancer, and is especially implicated
Externí odkaz:
https://doaj.org/article/f1e3283e142b4c92b62c47b377cd2337
Autor:
Li Li, Alejandro P. Ugalde, Colinda L. G. J. Scheele, Sebastian M. Dieter, Remco Nagel, Jin Ma, Abhijeet Pataskar, Gozde Korkmaz, Ran Elkon, Miao-Ping Chien, Li You, Pin-Rui Su, Onno B. Bleijerveld, Maarten Altelaar, Lyubomir Momchev, Zohar Manber, Ruiqi Han, Pieter C. van Breugel, Rui Lopes, Peter ten Dijke, Jacco van Rheenen, Reuven Agami
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-28 (2021)
Abstract Background Frequent activation of the co-transcriptional factor YAP is observed in a large number of solid tumors. Activated YAP associates with enhancer loci via TEAD4-DNA-binding protein and stimulates cancer aggressiveness. Although thous
Externí odkaz:
https://doaj.org/article/c775eb768cb945179e71e99f571ae872
Autor:
Ruiqi Han, Li Li, Alejandro Piñeiro Ugalde, Arieh Tal, Zohar Manber, Eric Pinto Barbera, Veronica Della Chiara, Ran Elkon, Reuven Agami
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background Functional characterization of non-coding elements in the human genome is a major genomic challenge and the maturation of genome-editing technologies is revolutionizing our ability to achieve this task. Oncogene-induced senescence
Externí odkaz:
https://doaj.org/article/9beca4cf6947428b9b80ba60a87929a5
Publikováno v:
PLoS Biology, Vol 17, Iss 11, p e3000481 (2019)
Data normalization is a critical step in RNA sequencing (RNA-seq) analysis, aiming to remove systematic effects from the data to ensure that technical biases have minimal impact on the results. Analyzing numerous RNA-seq datasets, we detected a preva
Externí odkaz:
https://doaj.org/article/729785b16fb243acafd7dc009b33414c
Autor:
Rina Rosin-Arbesfeld, Michal Kazelnik, Yarden Shor-Nareznoy, Ella H. Sklan, Tamar Evron, Shir Armoza-Eilat, Revital Kariv, Zohar Manber, Michal Caspi, Ran Elkon
Publikováno v:
Oncogenesis, Vol 10, Iss 9, Pp 1-11 (2021)
Oncogenesis
Oncogenesis
The Wnt signaling pathways play fundamental roles during both development and adult homeostasis. Aberrant activation of the canonical Wnt signal transduction pathway is involved in many diseases including cancer, and is especially implicated in the d
Autor:
Hila Sharim, Yuval Ebenstein, Yotam Abramson, Zohar Manber, Surajit Bhattacharya, Roded Sharan, Sapir Margalit, Hayk Barseghyan, Ran Elkon, Eric Vilain, Yi-Wen Chen
Publikováno v:
Bioinformatics
MotivationWhile promoter methylation is associated with reinforcing fundamental tissue identities, the methylation status of distant enhancers was shown by genome-wide association studies to be a powerful determinant of cell-state and cancer. With re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67c086f70773475af2bd38c6202eba1
https://doi.org/10.1101/2021.01.28.428654
https://doi.org/10.1101/2021.01.28.428654
Autor:
Eric Pintó Barberà, Alejandro Pineiro Ugalde, Ruiqi Han, Li Li, Ran Elkon, Zohar Manber, Reuven Agami, Arieh Tal, Veronica Della Chiara
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-13 (2018)
Genome Biology, 19:118
Genome Biology
Genome Biology, 19:118
Genome Biology
Background Functional characterization of non-coding elements in the human genome is a major genomic challenge and the maturation of genome-editing technologies is revolutionizing our ability to achieve this task. Oncogene-induced senescence, a cellu
Autor:
Zohar Manber, Behzad Moumbeini, Yongsoo Kim, Romy van Vliet, Lars Custers, Remco Nagel, Reuven Agami, Gozde Korkmaz, Rui Lopes, Ran Elkon, Pieter C van Breugel, Sonia Aristin Revilla, Wilbert Zwart
Publikováno v:
Cancer Letters, 436, 87-95. Elsevier Ireland Ltd
Lopes, R, Korkmaz, G, Revilla, S A, van Vliet, R, Nagel, R, Custers, L, Kim, Y, van Breugel, P C, Zwart, W, Moumbeini, B, Manber, Z, Elkon, R & Agami, R 2018, ' CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells ', Cancer Letters, vol. 436, pp. 87-95 . https://doi.org/10.1016/j.canlet.2018.08.018
Lopes, R, Korkmaz, G, Revilla, S A, van Vliet, R, Nagel, R, Custers, L, Kim, Y, van Breugel, P C, Zwart, W, Moumbeini, B, Manber, Z, Elkon, R & Agami, R 2018, ' CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells ', Cancer Letters, vol. 436, pp. 87-95 . https://doi.org/10.1016/j.canlet.2018.08.018
Breast cancer is the most prevalent type of malignancy in women with ∼1.7 million new cases diagnosed annually, of which the majority express ERα (ESR1), a ligand-dependent transcription factor. Genome-wide chromatin binding maps suggest that ERα
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8845cb8fdf08bbb66a83741bcc310d25
https://pure.eur.nl/en/publications/574a5697-1925-4c32-a6fb-8e720de1e1fe
https://pure.eur.nl/en/publications/574a5697-1925-4c32-a6fb-8e720de1e1fe