Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zohar Itzhaki"'
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 1, p e1002341 (2012)
Many protein-protein interactions are mediated by domain-motif interaction, where a domain in one protein binds a short linear motif in its interacting partner. Such interactions are often involved in key cellular processes, necessitating their tight
Externí odkaz:
https://doaj.org/article/be5d70eec58f4a169a9d1c9a8b5527f6
Autor:
Zohar Itzhaki, Hanah Margalit
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34503 (2012)
Genome sequencing of various individuals or isolates of the same species allows studying the polymorphism level of specific proteins and protein domains. Here we ask whether domains that are known to be involved in mediating protein-protein interacti
Externí odkaz:
https://doaj.org/article/e7d58ea5f96f46ff8a2d12e0d96dfcff
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 1 (2012)
Externí odkaz:
https://doaj.org/article/25f3e9381b53496f960cd792b14aa76c
Autor:
Zohar Itzhaki
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21724 (2011)
Protein-domains play an important role in mediating protein-protein interactions. Furthermore, the same domain-pairs mediate different interactions in different contexts and in various organisms, and therefore domain-pairs are considered as the build
Externí odkaz:
https://doaj.org/article/f968ec71eb884494933a743c15347af2
Autor:
Ohad Manor, Zohar Itzhaki, Diana Varol, Ido Amit, Steffen Jung, Ester Feldmesser, Eran Hornstein, Alexander Mildner, Tegest Aychek, Simon Yona, Ki-Wook Kim, Elik Chapnik, Gilad Beck
Publikováno v:
Blood. 121:1016-1027
The mononuclear phagocyte system comprises cells as diverse as monocytes, macrophages, and dendritic cells (DCs), which collectively play key roles in innate immune responses and the triggering of adaptive immunity. Recent studies have highlighted th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f60aee0cca25e41840b6696d13217949
https://doi.org/10.1182/blood-2012-07-445999
https://doi.org/10.1182/blood-2012-07-445999
Publikováno v:
Bioinformatics. 26:2564-2570
Motivation: Many protein–protein interactions (PPIs) are mediated by protein domains. The structural data of multi-domain PPIs reveal the domain pair (or pairs) that mediate a PPI, and implicitly also the domain pairs that are not involved in the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad55256fc9744d8ffa35d93e603b3bfb
https://doi.org/10.1093/bioinformatics/btq495
https://doi.org/10.1093/bioinformatics/btq495
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 38:324-336
The prevalence and morbidity of asthma, a chronic inflammatory airway disease, is increasing. Animal models provide a meaningful but limited view of the mechanisms of asthma in humans. A systems-level view of asthma that integrates multiple levels of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd86fd449df6f6a047e2870d21b30ceb
https://doi.org/10.1165/rcmb.2007-0151oc
https://doi.org/10.1165/rcmb.2007-0151oc
Autor:
Christine S. Cheng, Oren Ram, Brian Minie, Dennis C. Friedrich, Daniela Amann-Zalcenstein, Alon Goren, Chamutal Bornstein, James T. Robinson, Bang Wong, Mitchell Guttman, Andreas Gnirke, Sheila Fisher, Anne Thielke, Zohar Itzhaki, Assaf Weiner, Nir Yosef, James Meldrim, Ronnie Blecher-Gonen, Nir Friedman, Nir Hacohen, Raktima Raychowdhury, Bradley E. Bernstein, Manuel Garber, Ido Amit, Nicolas Chevrier, Aviv Regev, Chad Nusbaum
Understanding the principles governing mammalian gene regulation has been hampered by the difficulty in measuring in vivo binding dynamics of large numbers of transcription factors (TF) to DNA. Here, we develop a high-throughput Chromatin ImmunoPreci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a7f1cba9ee79737f923b0fc41b1be7
https://resolver.caltech.edu/CaltechAUTHORS:20161122-073136200
https://resolver.caltech.edu/CaltechAUTHORS:20161122-073136200
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 8, Iss 1 (2012)
PLoS Computational Biology, Vol 8, Iss 1 (2012)
The current addresses of Gilgi Friedlander and Zohar Itzhaki were incorrect. The correct current addresses are: ¤b Current address: Bioinformatics and Biological Computing Unit, Weizmann Institute of Science, Rehovot, Israel ¤c Current address: Dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061c02a57a597d3f3d566d3e8909fe87
https://doi.org/10.1371/annotation/2e21b1b9-46de-4cbe-a2a4-b4598d90d492
https://doi.org/10.1371/annotation/2e21b1b9-46de-4cbe-a2a4-b4598d90d492
Publikováno v:
Trends in genetics : TIG. 26(9)
Protein domain repeats within a protein sequence have been observed throughout all domains of life. Our analysis shows a significantly higher degree of sequence identity between repeated domains in prokaryotes compared to eukaryotes. We discuss this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead658c86681b772f1e9a12ab4125e91
https://pubmed.ncbi.nlm.nih.gov/20643491
https://pubmed.ncbi.nlm.nih.gov/20643491