Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Zohar Attias-Geva"'
Autor:
Stephanie A. Kujawski, Colleen Burgess, Oren Agi, Zohar Attias-Geva, Matthew Pillsbury, David Greenberg, Goran Bencina, Manjiri Pawaskar
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 6 (2022)
Currently available health economic models for varicella infection are designed to inform the cost-effectiveness of universal varicella vaccination (UVV) compared with no vaccination. However, in countries with an existing UVV program, these models c
Externí odkaz:
https://doaj.org/article/1ec9dd97e1f34a928819c89d73e7c5e3
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61537 (2013)
Accumulating epidemiological evidence shows that obesity is associated with an increased risk of several types of adult cancers, including endometrial cancer. Chronic hyperinsulinemia, a typical hallmark of diabetes, is one of the leading factors res
Externí odkaz:
https://doaj.org/article/faf1d7eac24148b4a762ff4bbebae9f3
Autor:
Ilan Bruchim, Haim Werner, Zohar Attias-Geva, Ami Fishman, Connie Bitelman, Menahem Sarig, Rive Sarfstein
Publikováno v:
Cancer letters. 335(1)
This study evaluated the potential ability of MK-0646 to inhibit IGF1-mediated biological actions and cell signaling events in Type 1 and Type 2 endometrial cancer. We found that MK-0646 treatment significantly decreased IGF1R expression. In addition
Autor:
Debora Kidron, Haim Werner, Zohar Attias-Geva, Hagit Schayek, Rive Sarfstein, Ami Fishman, Keren Amichay, Ilan Bruchim
Publikováno v:
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. 22(5)
Objective The insulin-like growth factor I receptor (IGF-IR) and BRCA1 affect cell growth and apoptosis. Little information is available about BRCA1 activity on the IGF signaling pathway. This study evaluated the effect of BRCA1 on IGF-IR expression.
Autor:
Hagit Schayek, Haim Werner, Rive Sarfstein, Ilan Bruchim, Zohar Attias-Geva, Doron Weinstein, Itay Bentov
Publikováno v:
Insulin-like Growth Factors and Cancer ISBN: 9781461405979
The IGF1-R displays potent antiapoptotic, prosurvival activities and has an important role in cell cycle progression. In addition, activation of the IGF1-R signaling pathway is a crucial prerequisite for malignant transformation. Overexpression of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56bbc808339afe493cbea8b7ab1214f7
https://doi.org/10.1007/978-1-4614-0598-6_8
https://doi.org/10.1007/978-1-4614-0598-6_8
Autor:
Rive Sarfstein, Ami Fishman, Itay Bentov, Keren Amichay, Ilan Bruchim, Zohar Attias-Geva, Haim Werner, Dvora Kidron
Publikováno v:
European journal of cancer (Oxford, England : 1990). 48(10)
The role of the insulin-like growth factors (IGF) in endometrial cancer has been well established. The IGF-I receptor (IGF-IR), which mediates the biological actions of IGF-I, is usually overexpressed in endometrial tumours. Uterine serous carcinoma
Publikováno v:
European journal of cancer (Oxford, England : 1990). 47(11)
Specific insulin-like growth factor-I receptor (IGF-IR) targeting emerged in recent years as a promising therapeutic strategy in cancer. Endometrial cancer is the most common gynaecological cancer in the Western world. The aim of this study was to ev
Publikováno v:
Gynecologic oncology. 121(2)
Purpose The role of the insulin-like growth factor (IGF) system in endometrial cancer has been well established. The IGF-I receptor (IGF-IR) emerged as a promising therapeutic target in a number of cancers. NVP-AEW541 (Novartis Pharma) is a pyrrolo(2