Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Zogopoulos P"'
Autor:
Jessica L. Nickerson, Chloe Cyr, Riley J. Arseneau, Stacey N. Lee, Stefanie Condon-Oldreive, George Zogopoulos, Keith Roberts, Christina A. Kim, Sylvia S. W. Ng, Masoom Haider, Eva Villalba, Leah Stephenson, Erica Tsang, Brent Johnston, Boris Gala-Lopez, Valerie Cooper, Breffni Hannon, Anne Gangloff, Sharlene Gill, Filomena Servidio-Italiano, Ravi Ramjeesingh
Publikováno v:
Current Oncology, Vol 31, Iss 10, Pp 6191-6204 (2024)
Pancreatic cancer is a complex malignancy associated with poor prognosis and high symptom burden. Optimal patient care relies on the integration of various sectors in the healthcare field as well as innovation through research. The Canadian National
Externí odkaz:
https://doaj.org/article/33a64f73423d4246991865032540b914
Autor:
Joan Miguel Romero, Emma Titmuss, Yifan Wang, James Vafiadis, Alain Pacis, Gun Ho Jang, Amy Zhang, Bryn Golesworthy, Tatiana Lenko, Laura M. Williamson, Barbara Grünwald, Grainne M. O’Kane, Steven J. M. Jones, Marco. A. Marra, Julie M. Wilson, Steven Gallinger, Janessa Laskin, George Zogopoulos
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-14 (2023)
Abstract Immune checkpoint inhibitors (ICI) are highly effective in specific cancers where canonical markers of antitumor immunity are used for patient selection. Improved predictors of T cell-inflammation are needed to identify ICI-responsive tumor
Externí odkaz:
https://doaj.org/article/8dd7df9c6c22430ba3c3588f08acd012
Akademický článek
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Autor:
Jannat Pervin, Mohammad Asad, Shaolong Cao, Gun Ho Jang, Nikta Feizi, Benjamin Haibe-Kains, Joanna M. Karasinska, Grainne M. O’Kane, Steven Gallinger, David F. Schaeffer, Daniel J. Renouf, George Zogopoulos, Oliver F. Bathe
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease characterized by a diverse tumor microenvironment. The heterogeneous cellular composition of PDAC makes it challenging to study molecular features of tumor cells using extracts f
Externí odkaz:
https://doaj.org/article/ec92d12728a044ddbf9be245d2f7b7e0
Structural Analysis is an established method for Fault Detection and Identification (FDI) in large-scale systems, enabling the discovery of Analytical Redundancy Relations (ARRs) which serve as residual generators. However, most techniques used to en
Externí odkaz:
http://arxiv.org/abs/1703.07611
Autor:
Mark Sorin, Sophie Camilleri-Broët, Emilie Pichette, Justin-Pierre Lorange, Nasim Haghandish, Laurie-Rose Dubé, André Lametti, Caroline Huynh, Leora Witkowski, George Zogopoulos, Yifan Wang, Hangjun Wang, Jonathan Spicer, Logan A. Walsh, Roni Rayes, Guy Rouleau, Alan Spatz, Andrea Liliam Gomez Corredor, Pierre Olivier Fiset
Publikováno v:
Cancer Treatment and Research Communications, Vol 35, Iss , Pp 100696- (2023)
Background: Lung cancer is the leading cause of cancer death in both men and women. Quebec has the highest lung cancer mortality out of all provinces in Canada, believed to be caused by higher smoking rates. Molecular testing for lung cancer is stand
Externí odkaz:
https://doaj.org/article/7240409f90f54785af03197a914fd316
Akademický článek
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Publikováno v:
Biology, Vol 12, Iss 9, p 1226 (2023)
The most common approach in transcriptomics (RNA-seq and microarrays) is differential gene expression analysis (DGEA) [...]
Externí odkaz:
https://doaj.org/article/32791dbd77914dc68616b6e0d5f83324
Autor:
Huairong Zhang, Andrea Liliam Gomez Corredor, Julia Messina-Pacheco, Qing Li, George Zogopoulos, Nancy Kaddour, Yifan Wang, Bing-yin Shi, Alex Gregorieff, Jun-li Liu, Zu-hua Gao
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Using several human and murine models, Zhang et al discover a role for the REG3A/REG3B proteins in acinar to ductal metaplasia (ADM), a precursor of pancreatic ductal adenocarcinoma (PDAC). They find that REG3B induces ADM through RAS-RAF-MEK-ERK sig
Externí odkaz:
https://doaj.org/article/187a4a144b6748659950952e1f8ad2db
Autor:
Bryn Golesworthy, Yifan Wang, Amanda Tanti, Alain Pacis, Joan Miguel Romero, Adeline Cuggia, Celine Domecq, Guillaume Bourdel, Robert E. Denroche, Gun Ho Jang, Robert C. Grant, Ayelet Borgida, Barbara T. Grünwald, Anna Dodd, Julie M. Wilson, Guillaume Bourque, Grainne M. O’Kane, Sandra E. Fischer, Chelsea Maedler Kron, Pierre-Olivier Fiset, Atilla Omeroglu, William D. Foulkes, Steven Gallinger, Marie-Christine Guiot, Zu-Hua Gao, George Zogopoulos
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The immune contexture of pancreatic ductal adenocarcinoma (PDAC) is generally immunosuppressive. A role for immune checkpoint inhibitors (ICIs) in PDAC has only been demonstrated for the rare and hypermutated mismatch repair (MMR) deficient (MMR-d) s
Externí odkaz:
https://doaj.org/article/05e7545055d64a62972ea705edc792bf