Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Zofia Zukowska-Grojec"'
Autor:
Sarah Spiegel, James R. Van Brocklyn, Fang Wang, Sharareh Movafagh, Sheldon Milstien, John P. Hobson, Zofia Zukowska-Grojec
Publikováno v:
Journal of Biological Chemistry. 274:35343-35350
Sphingosine 1-phosphate (SPP) has been shown to inhibit chemotaxis of a variety of cells, in some cases through intracellular actions, while in others through receptor-mediated effects. Surprisingly, we found that low concentrations of SPP (10-100 nM
Publikováno v:
Regulatory Peptides. :231-238
We have previously reported that neuropeptide Y (NPY), a sympathetic cotransmitter and vasoconstrictor, is mitogenic for vascular smooth muscle cells (VSMCs), and now report on the mechanisms mediating these effects. In rat aortic A10 cell line, NPY'
Autor:
Ewa Karwatowska-Prokopczuk, Hong Ji, Lois T. Hunt, Zofia Zukowska-Grojec, Candace B. Pert, Michael R. Ruff, Joon Kim
Publikováno v:
Regulatory Peptides. :201-205
Hyperplasia of vascular smooth muscle cells (VSMCs) occurs during HIV infection, part of a spectrum of HIV-mediated cardiovascular and microvascular pathologies. These changes are not due to direct viral infection but may involve the receptor-mediate
Autor:
H. Switalska, W. Januszewicz, M Elaffi, Jolanta Chodakowska, Zofia Zukowska-Grojec, B Wocial, Piotr Pruszczyk, J Lewandowski
Publikováno v:
Regulatory Peptides. :239-245
Some evidences indicate that the female sex hormones protect against the development of cardiovascular diseases. Modulation of sympathetic activity may be one of the possibilities. We investigated the influence of treadmill stress on blood pressure (
Publikováno v:
Regulatory Peptides. :215-220
Neuropeptide Y (1-36), NPY, is a sympathetic vasoconstrictor whose activities in blood vessels is determined by the presence of vasoconstrictive Y1 receptors and the enzyme dipeptidyl peptidase IV (DPPIV), which converts NPY to non-vasoconstrictive p
Autor:
M. P. Colvin, Gabriel J. Hauser, Zofia Zukowska-Grojec, Richard A. Hopkins, Adam K. Myers, M.R Danchak, B Wocial
Publikováno v:
Neuropeptides. 30:159-165
Neuropeptide-Y (NPY) is a sympathetic cotransmitter, which causes vasoconstriction, decreases coronary blood flow and decreases cardiac output. Circulating immunoreactive NPY (ir-NPY) levels increase with exercise, in patients admitted to the coronar
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 270:H796-H800
The physiological role of neuropeptide Y (NPY), a sympathetic cotransmitter and vasoconstrictor, has not been determined yet. We used a specific nonpeptide antagonist to the NPY Y1 receptor [BIBP-3226; (R)-N2-(diphenacetyl)-N-[(4-hydroxyphenyl) methy
Publikováno v:
International Journal of Immunopathology and Pharmacology. 9:1-8
Neuropeptide Y (NPY) is a multi-functional peptide localized in a number of tissues besides the brain, and its expression is high in strains of mice with autoimmune disease. Functionally, along with its neurotransmitter role, NPY has multiple effects
Publikováno v:
Life Sciences. 57:235-244
Hypotension during endotoxic shock is related to reduced vascular responsiveness to vasoconstrictors. Neuropeptide Y (NPY) is known to potentiate the pressor response to some agonists, and NPY infusion has been shown to improve hemodynamics and survi
Publikováno v:
Clinical Autonomic Research. 5:91-97
Modest increases in urinary bladder pressure result in acute hypertensive episodes in humans with spinal cord lesions above T5. The underlying mechanisms of this condition, referred to as autonomic dysreflexia, are not well understood. The aim of thi