Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Zofia Urbanczyk‐Lipkowska"'
Publikováno v:
Biomolecules, Vol 12, Iss 8, p 1116 (2022)
Background: Due to resistance to conventional therapy, a blood–brain barrier that results in poor drug delivery, and a high potential for metastasis, glioblastoma (GBM) presents a great medical challenge. Since the repertoire of the possible therap
Externí odkaz:
https://doaj.org/article/460a96cd8a3c4815ae7f4bf48855880b
Autor:
Oleg M. Demchuk, Aleksandra Martyna, Mateusz Kwaśnik, Katarzyna Szwaczko, Dorota Strzelecka, Barbara Mirosław, Kazimierz Michał Pietrusiewicz, Zofia Urbanczyk-Lipkowska
Publikováno v:
Molecules, Vol 27, Iss 17, p 5504 (2022)
The series of C2-symmetric biaryl core-based non-racemic bisphosphines possessing substituents of different electronic properties: both EDG and EWG were obtained in a short sequence of good yielding transformations, started from commercial 1,3-dimeth
Externí odkaz:
https://doaj.org/article/50e35981bb1b453cb57b4b0cd28f54b8
Publikováno v:
Molecules, Vol 20, Iss 1, Pp 738-753 (2015)
Antimicrobial drug resistance is a major human health threat. Among the many attempts to tackle this problem, the synthesis of antimicrobial compounds that mimic natural antimicrobial peptides appears as a promising approach. Peptide-based dendrimers
Externí odkaz:
https://doaj.org/article/980b6ef859e04af19595b34e1ae52491
Autor:
Marta Sowinska, Maja Morawiak, Marta Bochyńska-Czyż, Andrzej W. Lipkowski, Elżbieta Ziemińska, Barbara Zabłocka, Zofia Urbanczyk-Lipkowska
Publikováno v:
Biomolecules, Vol 9, Iss 3, p 89 (2019)
Background: Exposure to ozone level and ultraviolet (UV) radiation is one of the major concerns in the context of public health. Numerous studies confirmed that abundant free radicals initiate undesired processes, e.g. carcinogenesis, cells degenerat
Externí odkaz:
https://doaj.org/article/986f4cc0a67447119ae4d2df7c1638d4
Autor:
Paulina Zielinska, Magdalena Zimnicka, Anna Troć, Przemysław Kalicki, Jolanta Solecka, Anna Laskowska, Zofia Urbanczyk-Lipkowska, Piotr Polcyn
Publikováno v:
Molecules, Vol 18, Iss 6, Pp 7120-7144 (2013)
A series of new peptide dendrimers with amphiphilic surface, designed around a dendronized ornithine (Orn) core were synthesized and characterized by ESI-MS, 1H-, 13C- NMR, and CD spectrometry. An improved antimicrobial potency against S. aureus and
Externí odkaz:
https://doaj.org/article/5bdc3e9047f044499d3041ce7091a410
Autor:
Jolanta Janiszewska, Inmaculada Posadas, Pablo Játiva, Marta Bugaj-Zarebska, Zofia Urbanczyk-Lipkowska, Valentín Ceña
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165704 (2016)
Glioblastomas are the most common malignant primary brain tumours in adults and one of the most aggressive and difficult-to-treat cancers. No effective treatment exits actually for this tumour and new therapeutic approaches are needed for this diseas
Externí odkaz:
https://doaj.org/article/2a929ae6d22c47168c68b64652b58afa
Autor:
Zofia Urbanczyk-Lipkowska, Jolanta Solecka, Aleksandra Rajnisz, Margarita Jurczak, Piotr Polcyn
Publikováno v:
Molecules, Vol 14, Iss 10, Pp 3881-3905 (2009)
Novel polyfunctional small amphiphilic peptide dendrimers characterized by incorporation of a new core compounds – tris-amino acids or tetrakis-amino alcohols that originated from a series of basic amino acids – were efficiently synthesized. Thes
Externí odkaz:
https://doaj.org/article/77ce7defb752456798d0ff24cad7c6fc
Autor:
Marta Bochyńska-Czyż, Anna Laskowska, Adam Guśpiel, Zofia Urbanczyk-Lipkowska, Jolanta Solecka, Andrzej W. Lipkowski, Marta Sowinska, Katarzyna Trzeciak
Publikováno v:
Bioconjugate Chemistry. 29:3571-3585
Evolution-derived natural compounds have been inspirational for design of numerous pharmaceuticals, e.g., penicillins and tetracyclines. Herein, we present a bioinspired strategy to design peptide dendrimers for the effective therapy of E. coli infec
Autor:
Zofia Urbanczyk-Lipkowska, Monika Szeliga, Barbara Zabłocka, Marta Sowinska, Elzbieta Zieminska, Maja Morawiak
Publikováno v:
Biomolecules, Vol 11, Iss 435, p 435 (2021)
Biomolecules
Volume 11
Issue 3
Biomolecules
Volume 11
Issue 3
Background: Glioblastoma (GBM) is the most common malignant tumor of the central nervous system (CNS). Neuroblastoma (NB) is one of the most common cancers of childhood derived from the neural crest cells. The survival rate for patients with GBM and
Autor:
Koichi, Tanaka, Maya, Kinoshita, Jun, Kayahara, Yutaro, Uebayashi, Kazusada, Nakaji, Maja, Morawiak, Zofia, Urbanczyk-Lipkowska
Publikováno v:
RSC advances. 8(49)
An efficient asymmetric ring-opening (ARO) reaction of