Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Zofia Jahnz-Wechmann"'
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1326 (2021)
Aptamers constitute an answer for the growing need for targeted therapy development. One of the most well-known representatives of this group of compounds is thrombin binding aptamers (TBA) targeted towards thrombin. The TBA inhibitory activity is de
Externí odkaz:
https://doaj.org/article/381ea302eaad4a61b69c68d0d2a26a27
Autor:
Andrzej Manikowski, Daniel Baranowski, Joanna Fogt, Grzegorz Framski, Piotr Januszczyk, Zofia Jahnz-Wechmann, Dagmara Baraniak, Tomasz Ostrowski, Jerzy Boryski, Dariusz Wawrzyniak, Katarzyna Rolle
Publikováno v:
ChemistrySelect. 5:13370-13375
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::489c2266c7ce6b75f630cda5f948b4d0
https://doi.org/10.1002/slct.202003393
https://doi.org/10.1002/slct.202003393
Autor:
Jolanta Lisowiec-Wachnicka, Joanna Kosman, Anna Pasternak, Jerzy Boryski, Grzegorz Framski, Zofia Jahnz-Wechmann
Publikováno v:
Bioorganic Chemistry. 71:294-298
Herein, we present comprehensive physicochemical and structural analysis of various DNA hairpins modified with pyrrolo-2'-deoxycytidine (Py-dC) derivatives. The introduction of modified Py-dC in most cases causes minor decrease of hairpin thermodynam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c779154051580328415c193256d02b6
https://doi.org/10.1016/j.bioorg.2017.02.014
https://doi.org/10.1016/j.bioorg.2017.02.014
Autor:
Jan Barciszewski, Jacek Stawinski, Dariusz Wawrzyniak, Agnieszka Szymanska-Michalak, Adam Kraszewski, Zofia Jahnz-Wechmann, Jerzy Boryski, Grzegorz Framski
Publikováno v:
Acta Biochimica Polonica. 63
Several ribonucleoside analogues with modifications in the nucleobase and sugar moiety have been screened for anti-glioma activity in the T98G glioma cell line using cervical (HeLa) cell line as reference human malignant cells, and lung fibroblast (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc3dbb427e1e798363cee0c3bcef5f0
https://doi.org/10.18388/abp.2016_1338
https://doi.org/10.18388/abp.2016_1338
Publikováno v:
Frontiers in Chemistry
Frontiers in Chemistry, Vol 4 (2016)
Frontiers in Chemistry, Vol 4 (2016)
This review presents synthesis and chemistry of nucleoside analogs, possessing an additional fused, heterocyclic ring of the "etheno" type, such as 1,N(6)-ethenoadenosine, 1,N(4)-ethenocytidine, 1,N(2)-ethenoguanosine, and other related derivatives.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4426b07dfa6fdb9b4708d650407b84fe
http://europepmc.org/articles/PMC4848297
http://europepmc.org/articles/PMC4848297
Autor:
Katarzyna Adrych-Rożek, Jolanta Brzezinska, Zofia Jahnz-Wechmann, Wojciech T. Markiewicz, Jerzy Boryski
Publikováno v:
Scopus-Elsevier
This paper presents several analogs of nucleic acids, including their structure and selected physico-chemical properties, reported recently as being obtained from non-nucleosidic units connected via phosphorodiester bonds. These analogs are built fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1abdef8f3356040cbb8eb55558f050ea
https://doi.org/10.5114/bta.2012.46593
https://doi.org/10.5114/bta.2012.46593
Publikováno v:
ChemInform. 46
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86a807d61093f063482a077fe00be94f
https://doi.org/10.1002/chin.201532285
https://doi.org/10.1002/chin.201532285
Publikováno v:
European journal of medicinal chemistry. 97
The following mini-review summarizes the basic literature data regarding synthesis, biological activity, structure-activity relationship, and discussion of the mechanisms of action of two major classes of nucleoside analogs with fused heterocyclic ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ce68f064fa59b075faf29efb7583bd
https://pubmed.ncbi.nlm.nih.gov/25576500
https://pubmed.ncbi.nlm.nih.gov/25576500
Autor:
Zofia Jahnz-Wechmann, Jerzy Boryski, Kunisuke Izawa, Tomoyuki Onishi, Erik De Clercq, Johan Neyts
Publikováno v:
ChemInform. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4fd2f549082299208bc8fb1949130a8
https://doi.org/10.1002/chin.200811253
https://doi.org/10.1002/chin.200811253
Autor:
Zofia Jahnz-Wechmann, Erik De Clercq, Johan Neyts, Kunisuke Izawa, Jerzy Boryski, Tomoyuki Onishi
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 26(8-9)
A series of novel analogs of acyclovir, substituted with an alkyl (methyl, ethyl, n-butyl) or phenyl group at the positions 1', 4', and/or 5', has been obtained in a direct one-pot coupling reaction of guanosine and the respective 1,3-dioxolanes. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69376800f1ccd52803af1566adb07df
https://pubmed.ncbi.nlm.nih.gov/18058508
https://pubmed.ncbi.nlm.nih.gov/18058508