DNA Physical Properties and Nucleosome Positions Are Major Determinants of HIV-1 Integrase Selectivity.

Autor: Monica Naughtin, Zofia Haftek-Terreau, Johan Xavier, Sam Meyer, Maud Silvain, Yan Jaszczyszyn, Nicolas Levy, Vincent Miele, Mohamed Salah Benleulmi, Marc Ruff, Vincent Parissi, Cédric Vaillant, Marc Lavigne

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0129427 (2015)

Retroviral integrases (INs) catalyse the integration of the reverse transcribed viral DNA into the host cell genome. This process is selective, and chromatin has been proposed to be a major factor regulating this step in the viral life cycle. However

Externí odkaz: https://doaj.org/article/c7cf239038bd474bba473401f2b665c5

The Neurodevelopmental Gene MSANTD2 Belongs to a Gene Family Formed by Recurrent Molecular Domestication of Harbinger Transposons at the Base of Vertebrates

Autor: Ema Etchegaray, Dominique Baas, Magali Naville, Zofia Haftek-Terreau, Jean Nicolas Volff

Publikováno v: Molecular Biology and Evolution. 39

The formation of new genes is a major source of organism evolutionary innovation. Beyond their mutational effects, transposable elements can be co-opted by host genomes to form different types of sequences including novel genes, through a mechanism n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1286bf9e15d847f5383433f80a46f09f
https://doi.org/10.1093/molbev/msac173

Fluorescent RAFT polymers bearing a nitrilotriacetic acid (NTA) ligand at the α-chain-end for the site-specific labeling of histidine-tagged proteins

Autor: Marie-Thérèse Charreyre, Matthieu Carretier, Zofia Haftek-Terreau, Arnaud Favier, Catherine Ladavière, Damien Duret

Publikováno v: Polymer Chemistry
Polymer Chemistry, Royal Society of Chemistry-RSC, 2017, 8 (10), pp.1611-1615. ⟨10.1039/c6py02222g⟩
Polymer Chemistry, 2017, 8 (10), pp.1611-1615. ⟨10.1039/c6py02222g⟩

Site-specific labeling of proteins is a valuable tool to study biological processes. We show that it can be achieved using fluorescent polymer probes synthesized by RAFT polymerization. Thanks to an original control agent functionalized with a nitril

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c532a40990cd4072d1a0f18c98e4ba1a
https://hal.archives-ouvertes.fr/hal-02293372

Craniofacial cartilage morphogenesis requires zebrafish col11a1 activity

Autor: Zofia Haftek-Terreau, Dominique Baas, Maryline Malbouyres, Dominique Le Guellec, Florence Ruggiero

Publikováno v: Matrix Biology. 28:490-502

The zebrafish ortholog of the human COL11A1 gene encoding the cartilage collagen XI proalpha1 chain was characterized to explore its function in developing zebrafish using the morpholino-based knockdown strategy. We showed that its expression in zebr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13ce5f19446179d8f8432336ad10f0c
https://doi.org/10.1016/j.matbio.2009.07.004

Not so bad after all: retroviruses and long terminal repeat retrotransposons as a source of new genes in vertebrates

Autor: Frédéric Brunet, Domitille Chalopin, Ian A. Warren, Magali Naville, Jean-Nicolas Volff, Zofia Haftek-Terreau, P. Levin, Delphine Galiana

Publikováno v: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 22(4)

Viruses and transposable elements, once considered as purely junk and selfish sequences, have repeatedly been used as a source of novel protein-coding genes during the evolution of most eukaryotic lineages, a phenomenon called 'molecular domesticatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb063c388195ba06734ebd7b20089abe
https://pubmed.ncbi.nlm.nih.gov/26899828