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Autor:
van Kuilenburg, A.B. P.1 (AUTHOR) a.b.vankuilenburg@amc.uva.nl, Zoetekouw, L.1 (AUTHOR), Meijer, J.1 (AUTHOR), Kuijpers, T.W.2 (AUTHOR)
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. Apr-Jun2010, Vol. 29 Issue 4-6, p461-465. 5p. 4 Graphs.
Autor:
van Kuilenburg, A.B. P.1 (AUTHOR) a.b.vankuilenburg@amc.uva.nl, Zoetekouw, L.1 (AUTHOR), Meijer, J.1 (AUTHOR), Kuijpers, T.W.2 (AUTHOR)
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. Apr-Jun2010, Vol. 29 Issue 4-6, p466-470. 5p. 3 Graphs.
Autor:
van Kuilenburg, A.B. P.1 (AUTHOR) a.b.vanKuilenburg@amc.uva.nl, Zoetekouw, L.1 (AUTHOR)
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. Sep2006, Vol. 25 Issue 9-11, p1261-1264. 4p. 1 Graph.
Autor:
Van Kuilenburg, A. B.P., Zoetekouw, L.
Publikováno v:
Nederlands Tijdschrift voor Klinische Chemie en Laboratoriumgeneeskunde, 31(3), 219-220. Nederlandse Vereniging voor Klinische Chemie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::c867f5fa0c89c2bbf1330c3b4c7ea3bb
https://pure.amc.nl/en/publications/determination-of-thymidine-phosphorylase-activity-by-a-nonradiochemical-assay-using-reversedphase-highperformance-liquid-chromatography(72f7b635-e1be-4ff5-9918-d81e79b4ec7c).html
https://pure.amc.nl/en/publications/determination-of-thymidine-phosphorylase-activity-by-a-nonradiochemical-assay-using-reversedphase-highperformance-liquid-chromatography(72f7b635-e1be-4ff5-9918-d81e79b4ec7c).html
Publikováno v:
Nederlands tijdschrift voor klinische chemie en laboratoriumgeneeskunde, 29, 271-272
Scopus-Elsevier
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::13de2e90c6db83332d40dd32a7c79a5a
https://pure.amc.nl/en/publications/cyclopentenyl-cytosine-sensitises-sknbe2c-neuroblastoma-cells-to-cladribine(4962a453-dce8-4ea0-a483-72e5eff823e9).html
https://pure.amc.nl/en/publications/cyclopentenyl-cytosine-sensitises-sknbe2c-neuroblastoma-cells-to-cladribine(4962a453-dce8-4ea0-a483-72e5eff823e9).html
Autor:
Peter Vreken, van Gennip Ah, Van Lenthe H, Zoetekouw L, Hans R. Waterham, Janet Haasjes, van Kuilenburg Ab
Publikováno v:
Purine and Pyrimidine Metabolism in Man X ISBN: 9780306465154
Dihydropyrimidine dehydrogenase (DPD, EC 1.3.1.2) is responsible for the breakdown of the widely used chemotherapeutic agent 5-fluorouracil (5FU), thereby limiting the efficacy of the therapy. Because 5FU has a relative narrow therapeutic index, toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::297d2012f38ba1f4f82cedaff6e9e64d
https://doi.org/10.1007/0-306-46843-3_49
https://doi.org/10.1007/0-306-46843-3_49
Autor:
van Kuilenburg, A. B., Muller, E. W., Haasjes, J., Meinsma, R., Zoetekouw, L., Waterham, H. R., Baas, F., Richel, D. J., van Gennip, A. H.
Publikováno v:
Clinical cancer research, 7(5), 1149-1153. American Association for Cancer Research Inc.
Dihydropyrimidine dehydrogenase (DPD) is the initial and rate-limiting enzyme in the catabolism of 5-fluorouracil (5FU), and it is suggested that patients with a partial deficiency of this enzyme are at risk from developing a severe 5FU-associated to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::c49fdfae88e1027b445f4d3cf10ba283
https://pure.amc.nl/en/publications/lethal-outcome-of-a-patient-with-a-complete-dihydropyrimidine-dehydrogenase-dpd-deficiency-after-administration-of-5fluorouracil-frequency-of-the-common-ivs141ga-mutation-causing-dpd-deficiency(5de58691-4b54-443f-bc91-31d966c4e5b7).html
https://pure.amc.nl/en/publications/lethal-outcome-of-a-patient-with-a-complete-dihydropyrimidine-dehydrogenase-dpd-deficiency-after-administration-of-5fluorouracil-frequency-of-the-common-ivs141ga-mutation-causing-dpd-deficiency(5de58691-4b54-443f-bc91-31d966c4e5b7).html
Autor:
van Kuilenburg, A. B., Haasjes, J., Richel, D. J., Zoetekouw, L., van Lenthe, H., de Abreu, R. A., Maring, J. G., Vreken, P., van Gennip, A. H.
Publikováno v:
Clinical cancer research, 6(12), 4705-4712. American Association for Cancer Research Inc.
Dihydropyrimidine dehydrogenase (DPD) is the initial and rate-limiting enzyme in the catabolism of 5-fluorouracil (5FU), and it is suggested that patients with a partial deficiency of this enzyme are at risk for developing a severe 5FU-associated tox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::69af8033f37d98abe0fad4099bbf36c8
https://pure.amc.nl/en/publications/clinical-implications-of-dihydropyrimidine-dehydrogenase-dpd-deficiency-in-patients-with-severe-5fluorouracilassociated-toxicity-identification-of-new-mutations-in-the-dpd-gene(48b1c41b-90d0-4215-b319-ce36dec9e525).html
https://pure.amc.nl/en/publications/clinical-implications-of-dihydropyrimidine-dehydrogenase-dpd-deficiency-in-patients-with-severe-5fluorouracilassociated-toxicity-identification-of-new-mutations-in-the-dpd-gene(48b1c41b-90d0-4215-b319-ce36dec9e525).html
Autor:
Kuilenburg, A.B.P. van, Haasjes, J., Richel, D.J., Zoetekouw, L., Lenthe, G.H. van, Abreu, R.A. de, Maring, J.G., Vreken, P., Gennip, A.H. van
Publikováno v:
Clinical Cancer Research, 6, 4705-4712
Clinical Cancer Research, 6, pp. 4705-4712
Clinical Cancer Research, 6, pp. 4705-4712
Item does not contain fulltext 8 p.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b0269a564d7d7df10d9c1f7693184e75
http://hdl.handle.net/2066/185895
http://hdl.handle.net/2066/185895