Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Zoe Underwood"'
Autor:
Sarah Ross, Michael Niedbala, Sabina Cosulich, Zoe Underwood, Eleanor Wigmore, Alison Peter, Carla P. Martins, Lukasz Magiera, Jason G. Kettle, Giovanni Ciotta, Ivan del Barco Barrantes, Tamara Baker, James Atkinson, Alex Koers, Rebecca Whiteley, Radoslaw Polanski, Michael Davies, Sue Bickerton, Hilary Lewis, David Robinson, Lyndsey Hanson, Atanu Chakraborty
Supplementary Data from AZD4625 is a Potent and Selective Inhibitor of KRASG12C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af8725b786ab7b470d22cf3bb924324
https://doi.org/10.1158/1535-7163.22523586.v1
https://doi.org/10.1158/1535-7163.22523586.v1
Autor:
Sarah Ross, Michael Niedbala, Sabina Cosulich, Zoe Underwood, Eleanor Wigmore, Alison Peter, Carla P. Martins, Lukasz Magiera, Jason G. Kettle, Giovanni Ciotta, Ivan del Barco Barrantes, Tamara Baker, James Atkinson, Alex Koers, Rebecca Whiteley, Radoslaw Polanski, Michael Davies, Sue Bickerton, Hilary Lewis, David Robinson, Lyndsey Hanson, Atanu Chakraborty
Supplementary Figure from AZD4625 is a Potent and Selective Inhibitor of KRASG12C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040a8dea15a3d11c94aef8426fadb286
https://doi.org/10.1158/1535-7163.22523583
https://doi.org/10.1158/1535-7163.22523583
Autor:
Atanu Chakraborty, Lyndsey Hanson, David Robinson, Hilary Lewis, Sue Bickerton, Michael Davies, Radoslaw Polanski, Rebecca Whiteley, Alex Koers, James Atkinson, Tamara Baker, Ivan del Barco Barrantes, Giovanni Ciotta, Jason G. Kettle, Lukasz Magiera, Carla P. Martins, Alison Peter, Eleanor Wigmore, Zoe Underwood, Sabina Cosulich, Michael Niedbala, Sarah Ross
Publikováno v:
Molecular cancer therapeutics. 21(10)
AZD4625 is a potent, selective, and orally bioavailable inhibitor of oncogenic KRASG12C as demonstrated in cellular assays and in vivo in preclinical cell line–derived and patient-derived xenograft models. In vitro and cellular assays have shown se